Development of a Trypanosoma cruzi strain typing assay using MS2 peptide spectral libraries (Tc-STAMS2).

Autor: Gilberto Santos de Oliveira, Rebeca Kawahara, Livia Rosa-Fernandes, Simon Ngao Mule, Carla Cristi Avila, Marta M G Teixeira, Martin R Larsen, Giuseppe Palmisano

Publikováno v: PLoS Neglected Tropical Diseases, Vol 12, Iss 4, p e0006351 (2018)

Chagas disease also known as American trypanosomiasis is caused by the protozoan Trypanosoma cruzi. Over the last 30 years, Chagas disease has expanded from a neglected parasitic infection of the rural population to an urbanized chronic disease, beco

Externí odkaz: https://doaj.org/article/1ae1bac2f0234aa5bbe237ca12e71c2c

PhyloQuant approach provides insights into Trypanosoma cruzi evolution using a systems-wide mass spectrometry-based quantitative protein profile

Autor: Carla M. F. Rodrigues, Graziella E. Rosein, Gilberto Santos de Oliveira, Livia Rosa-Fernandes, Giuseppe Palmisano, Daniel Quina, André G. Costa-Martins, Marta Maria Geraldes Teixeira, Simon Ngao Mule

Publikováno v: Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Communications Biology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

The etiological agent of Chagas disease, Trypanosoma cruzi, is a complex of seven genetic subdivisions termed discrete typing units (DTUs), TcI-TcVI and Tcbat. The relevance of T. cruzi genetic diversity to the variable clinical course of the disease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18aad8bfa9d2d495294bdf04619826f8
https://doaj.org/article/dde00abd6afc4474a308f48f0fe9f7b4

Systems-wide analysis of glycoprotein conformational changes by limited deglycosylation assay

Autor: Vinícius M. Gomes, Simon Ngao Mule, Daniel Quina, Martin R. Larsen, Veronica Feijoli Santiago, Morten Thaysen-Andersen, Leticia Labriola, Gilberto Santos de Oliveira, Livia Rosa-Fernandes, Giuseppe Palmisano, Joao V.P. Coutinho, Janaina Macedo-da-Silva

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Mule, S N, Rosa-Fernandes, L, Coutinho, J V P, Gomes, V D M, Macedo-da-Silva, J, Santiago, V F, Quina, D, de Oliveira, G S, Thaysen-Andersen, M, Larsen, M R, Labriola, L & Palmisano, G 2021, ' Systems-wide analysis of glycoprotein conformational changes by limited deglycosylation assay ', Journal of Proteomics, vol. 248, 104355 . https://doi.org/10.1016/j.jprot.2021.104355

A new method to probe the conformational changes of glycoproteins on a systems-wide scale, termed limited deglycosylation assay (LDA), is described. The method measures the differential rate of deglycosylation of N-glycans on natively folded proteins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838e769f551cebc8bf7dc432dfdd3642
https://doi.org/10.1101/2021.06.04.447131

Cellular Imprinting Proteomics Assay:A Novel Method for Detection of Neural and Ocular Disorders Applied to Congenital Zika Virus Syndrome

Autor: Rossana C. N. Melo, Gilberto Santos de Oliveira, Jennifer E. Van Eyk, Martin R. Larsen, Giuseppe Palmisano, Raquel Hora Barbosa, Thiago P. Silva, Livia Rosa-Fernandes, Claudete Aparecida Araújo Cardoso, Claudia Blanes Angeli, Maria Luiza B. dos Santos, Bernardo Lemos

Publikováno v: Rosa-Fernandes, L, Barbosa, R H, Dos Santos, M L B, Angeli, C B, Silva, T P, Melo, R C N, de Oliveira, G S, Lemos, B, Van Eyk, J E, Larsen, M R, Cardoso, C A & Palmisano, G 2020, ' Cellular Imprinting Proteomics Assay : A Novel Method for Detection of Neural and Ocular Disorders Applied to Congenital Zika Virus Syndrome ', Journal of proteome research, vol. 19, no. 11, pp. 4496-4515 . https://doi.org/10.1021/acs.jproteome.0c00320
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Journal of Proteome Research

Congenital Zika syndrome was first described due to increased incidence of congenital abnormalities associated with Zika virus (ZIKV) infection. Since the eye develops as part of the embryo central nervous system (CNS) structure, it becomes a special

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc0923ac54fb470d6ecc4f221460903
https://findresearcher.sdu.dk:8443/ws/files/175380963/Cellular_Imprinting_Proteomics_Assay_A_novel_method_for_detection_of.pdf

Proteome-Wide Analysis of Trypanosoma cruzi Exponential and Stationary Growth Phases Reveals a Subcellular Compartment-Specific Regulation

Autor: Claudio Romero Farias Marinho, Simon Ngao Mule, Marta Maria Geraldes Teixeira, Giuseppe Palmisano, Livia Rosa-Fernandes, Gilberto Santos de Oliveira, María Julia Barisón, Rosa Viner, André Guillherme Costa-Martins, Ariel Mariano Silber, Carla Cristi Avila

Publikováno v: Genes, Vol 9, Iss 8, p 413 (2018)
GENES
Avila, C C, Mule, S N, Rosa-Fernandes, L, Viner, R, Barisón, M J, Costa-Martins, A G, de Oliveira, G S, Teixeira, M M G, Marinho, C R F, Silber, A M & Palmisano, G 2018, ' Proteome-wide analysis of Trypanosoma cruzi exponential and stationary growth phases reveals a subcellular compartment-specific regulation ', Genes, vol. 9, no. 8, 413 . https://doi.org/10.3390/genes9080413
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Genes
Volume 9
Issue 8

Trypanosoma cruzi, the etiologic agent of Chagas disease, cycles through different life stages characterized by defined molecular traits associated with the proliferative or differentiation state. In particular, T. cruzi epimastigotes are the replica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4edc92376c35af5ebf6e731c470badf
http://www.mdpi.com/2073-4425/9/8/413