Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Gilberto Magliacani"'
Publikováno v:
Wound Repair and Regeneration. 13:255-261
Epilysin, designated matrix metalloproteinase (MMP)-28, is the newest member of this family of proteases expressed by keratinocytes in response to an injury. MMP-28's physiological role and specific substrates are unknown, but its expression pattern
Autor:
Raffaella Casimiri, Irene Cambieri, Carlotta Castagnoli, Simone Teich Alasia, Maurizio Stella, Daniela Alotto, Gilberto Magliacani, Matteo Aluffi
Publikováno v:
Burns. 29:759-767
Cell viability assessment in allograft skin is an essential step to ensure a supply of good quality allograft skin for clinical repair of wounds. It is widely recognised that ‘take’ of allografts is strongly influenced grafted by tissue viability
Autor:
Silvia Ariotti, Tiziana Musso, Gilberto Magliacani, C. Trombotto, Carlotta Castagnoli, Francesco Novelli, Maurizio Stella, Daniela Ravarino, Alessandro Negro Ponzi, Maura Millesimo, Simone Teich-Alasia
Publikováno v:
Journal of Investigative Dermatology. 113:238-245
Hypertrophic scarring is a skin disorder that occurs after wounding and thermal injury. There is accumulating evidence that immunologic processes such as infiltration of activated T lymphocytes and altered cytokine production may play a role in the f
Autor:
Maurizio Calcagni, S. Teich Alasia, Gilberto Magliacani, Carlotta Castagnoli, C. Trombotto, Maurizio Stella
Publikováno v:
European Journal of Plastic Surgery. 21:8-13
It has been suggested that immunological factors play a major role in the pathogenesis of hypertrophic scars. Characteristically there is an onset of typical clinical features and, after a variable period of activity, there is a phase of remission. T
Autor:
Gilberto Magliacani, Carlotta Castagnoli, Maurizio Stella, Simone Teich Alasia, C. Trombotto, Sabzima Ondei, Maurizio Calcagni
Publikováno v:
Burns. 23:565-572
In this study, skin-infiltrating cells were characterized in both the active and remission phases of post-burn hypertrophic scar biopsies. Immunohistochemistry examination of active phase samples showed an abundant presence of Langerhans cells, T cel
Publikováno v:
European Journal of Plastic Surgery. 20:145-149
Reconstruction of skin defects of the distal third of the leg and foot is often a difficult task. Shape, resistance to shearing stresses in the weight-bearing surface and sensibility are the main features that have to be restored. For coverage of thi
Autor:
Carlotta Castagnoli, D. Peruccio, S. Teich Alasia, P. Richiardi Momigliano, Maurizio Stella, Sandra D'Alfonso, Gilberto Magliacani
Publikováno v:
Burns. 20:118-121
The present study shows that the decrease of TNF alpha in postburn hypertrophic scars is due to a decrease in the steady-state level of TNF alpha mRNA and thus to an altered biosynthesis of the cytokine. Thirteen scars, including seven hypertrophic a
Autor:
Maurizio Stella, Gilberto Magliacani, Patricia Momigliano Richiardi, Chiara Berthod, Carlotta Castagnoli
Publikováno v:
Cellular Immunology. 147:51-63
The percentage of TNF alpha- and beta-positive cells was analyzed in hypertrophic scar (N = 13), normotrophic scar (N = 7), and normal skin (N = 6) biopsies using monoclonal antibodies and immunoperoxidase staining of cryostat tissue sections. Sample
Autor:
Filippo Renò, Maurizio Stella, Carla Pezzuto, Mario Cannas, Maurizio Sabbatini, Francesca Lombardi, Gilberto Magliacani
Publikováno v:
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 11(5)
Hypertrophic scars resulting from severe burns are usually treated by continuous elastic compression. Although pressure therapy reaches success rates of 60-85% its mechanisms of action are still poorly understood. In this study, apoptosis induction a
Autor:
Filippo Renò, Mario Cannas, Gilberto Magliacani, Maurizio Stella, Carla Pezzuto, Paola Grazianetti
Publikováno v:
Archives of dermatology. 138(4)
Objective To investigate induction of matrix metalloproteinases (MMPs) during mechanical compression of hypertrophic scars. Mechanical pressure blocks hypertrophy inducted on extracellular matrix in scars by a mechanism that involves MMP-2 (gelatinas