Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Gilberto Coppi"'
Publikováno v:
Drug Delivery. 18:26-37
Polysaccharide microparticles for the oral administration of gentamicin were designed in order to obtain an increased drug absorption by means of microparticle transport across the intestinal epithelia. Alginate/chitosan microparticles with a size of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02963195b96b2616f7cf4db28542fac
https://doi.org/10.3109/10717544.2010.509362
https://doi.org/10.3109/10717544.2010.509362
Autor:
Gilberto Coppi, Valentina Iannuccelli
Publikováno v:
International Journal of Pharmaceutics. 367:127-132
Oral administration of the nonsteroidal anti-estrogen tamoxifen (TMX) is the treatment of choice for metastatic estrogen receptor-positive breast cancer. With the aim to improve TMX oral bioavailability and decrease its side effects, crosslinked algi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406aeedac967d9b65bd3ff63cd6e4023
https://doi.org/10.1016/j.ijpharm.2008.09.040
https://doi.org/10.1016/j.ijpharm.2008.09.040
Publikováno v:
Journal of Pharmacy and Pharmacology. 60:21-26
Fluorescent calcium alginate/chitosan microparticles, prepared using a spray-drying technique followed by crosslinking reactions with calcium ions and chitosan, were assayed in-vivo for polymyxin B (PMB) oral toxicity, uptake by Peyer's patches and P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024b17af06d546ce8a4b80591b479a92
https://doi.org/10.1211/jpp.60.1.0003
https://doi.org/10.1211/jpp.60.1.0003
Publikováno v:
Scopus-Elsevier
An air compartment multiple-unit system composed of a calcium alginate core separated by an air compartment from a calcium alginate/PVA membrane has shown excellent in vivo buoyancy ability and prolonged gastric residence time (GRT) in previous publi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85ee38d26bc8a0530150442f4802f10
https://doi.org/10.1016/s1773-2247(04)50024-2
https://doi.org/10.1016/s1773-2247(04)50024-2
Autor:
Gilberto Coppi, Valentina Iannuccelli, Maria Teresa Bernabei, Eliana Grazia Leo, Riccardo Cameroni
Publikováno v:
Journal of Microencapsulation. 19:37-44
Oral administration of peptide and protein drugs requires their protection from the acidic and enzymatic degradation in the gastro-intestinal environment and their targeting to the absorption zone. For this purpose, an alginate microsystem, as a carr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cdf8eae42d9a02b3a188e69a92f9614
https://doi.org/10.1080/02652040110055621
https://doi.org/10.1080/02652040110055621
Lipid-based particulate delivery systems have been extensively investigated in the last decade for both pharmaceutical and cosmetic skin application although their translocation across the skin is not yet clarified. The aim of this paper was to inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6efb74ed88c678ed58931bc76ef09c73
http://www.sciencedirect.com/science/article/pii/S0378517313002111
http://www.sciencedirect.com/science/article/pii/S0378517313002111
Autor:
Maria Angela Vandelli, Maria Teresa Bernabei, Valentina Iannuccelli, Gilberto Coppi, Eliana Grazia Leo
Publikováno v:
Drug Development and Industrial Pharmacy. 21:2307-2322
Coated beads were prepared by soaking in sodium alginate solutions spherical matrices (beads) of carboxymethylcellulose crosslinked with aluminum chloride (AlCl3) and loaded with ambroxol hydrochloride as a model drug. The residual amount of the cros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44772ef3c21da415ae90415378fc9da8
https://doi.org/10.3109/03639049509070871
https://doi.org/10.3109/03639049509070871
Autor:
Monica Montanari, Valentina Iannuccelli, Miriam Hanuskova, Eleonora Vighi, Gilberto Coppi, Eliana Grazia Leo
Publikováno v:
International journal of pharmaceutics. 440(2)
Several advanced in vitro and in vivo studies have proved the broad potential of cationic solid lipid nanoparticles (SLN) as nonviral vectors. However, a few data are available about the correlation between lipid component of the SLN structure and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9feedefa93b8b436f75fb07aa1815854
https://pubmed.ncbi.nlm.nih.gov/22982257
https://pubmed.ncbi.nlm.nih.gov/22982257
Lipid microparticles loaded with the complex between hydroxypropyl-β-cyclodextrin (HP-β-CD) and the sunscreen agent, butyl methoxydibenzoylmethane (BMDBM) were evaluated for their effect on the UV filter percutaneous penetration. The microparticles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac167b9a1e8d3b2975d2a007b67c0d8
https://hdl.handle.net/11380/645371
https://hdl.handle.net/11380/645371
Publikováno v:
International journal of pharmaceutics. 385(1-2)
Alginate/chitosan microparticles with a mean size less than 1 microm, designed in a previous work for the targeting of polymyxin B to M-cells and, then, to the lymphatic system, were assayed for transport ability by enterocytes. Caco-2 cell monolayer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3931c748cda2d47f6c60cc57a7bc5951
https://pubmed.ncbi.nlm.nih.gov/19837148
https://pubmed.ncbi.nlm.nih.gov/19837148