Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Gilbert Thomas Black"'
Autor:
Gilbert Thomas-Black, Andrada Dumitrascu, Hector Garcia-Moreno, Julie Vallortigara, Julie Greenfield, Barry Hunt, Susan Walther, Mackenzie Wells, David R. Lynch, Hugh Montgomery, Paola Giunti
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-10 (2022)
Abstract Background The development of new therapies may rely on the conduct of human experimentation as well as later clinical trials of therapeutic interventions. Ethical considerations seek to protect the patient from risk but few have sought to a
Externí odkaz:
https://doaj.org/article/7cdfe06b3261409aa3b0c3ebccaa3625
Stem cell research is one of the leading “cutting edge” areas of life science research in the world today and is a topic of significant interest to a broad range of the medical and scientific community. This authoritative book provides reviews by
Autor:
Anna M. Zeitlberger, Gilbert Thomas-Black, Hector Garcia-Moreno, Martha Foiani, Amanda J. Heslegrave, Henrik Zetterberg, Paola Giunti
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Background: Friedreich’s ataxia (FRDA) is the most common autosomal recessive ataxia. Disease-modifying treatments are not available yet; however, several compounds are currently under investigation. As a result, there is a growing need for the ide
Externí odkaz:
https://doaj.org/article/8699012435b74306bee3db31ed991dd9
Autor:
Gilbert Thomas‐Black, Daniel R. Altmann, Harry Crook, Nita Solanky, Ferran Prados Carrasco, Marco Battiston, Francesco Grussu, Marios C. Yiannakas, Baris Kanber, Jasleen K. Jolly, Jon Brett, Susan M. Downes, Marni Moran, Ping K. Chan, Emmanuel Adewunmi, Claudia A.M. Gandini Wheeler‐Kingshott, Andrea H. Németh, Richard Festenstein, Fion Bremner, Paola Giunti
Optic neuropathy is a near ubiquitous feature of Friedreich's ataxia (FRDA). Previous studies have examined varying aspects of the anterior and posterior visual pathways but none so far have comprehensively evaluated the heterogeneity of degeneration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f811871f92d3a5ab2b82398c806fc962
http://hdl.handle.net/10044/1/103490
http://hdl.handle.net/10044/1/103490
Publikováno v:
Cerebellum (London, England)
Auditory neural impairment is a key clinical feature of Friedreich’s Ataxia (FRDA). We aimed to characterize the phenotypical spectrum of the auditory impairment in FRDA in order to facilitate early identification and timely management of auditory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f438c55cad99a3b593e10fbf027e0d
https://doi.org/10.1007/s12311-021-01236-9
https://doi.org/10.1007/s12311-021-01236-9
Autor:
Hector Garcia‐Moreno, Mercedes Prudencio, Gilbert Thomas‐Black, Nita Solanky, Karen R. Jansen‐West, Rana Hanna AL‐Shaikh, Amanda Heslegrave, Henrik Zetterberg, Magda M. Santana, Luis Pereira de Almeida, Ana Vasconcelos‐Ferreira, Cristina Januário, Jon Infante, Jennifer Faber, Thomas Klockgether, Kathrin Reetz, Mafalda Raposo, Ana F. Ferreira, Manuela Lima, Ludger Schöls, Matthis Synofzik, Jeannette Hübener‐Schmid, Andreas Puschmann, Sorina Gorcenco, Zbigniew K. Wszolek, Leonard Petrucelli, Paola Giunti
Publikováno v:
Eur J Neurol . 2022 Aug;29(8):2439-2452
European journal of neurology 29(8), 2439-2452 (2022). doi:10.1111/ene.15373
European journal of neurology 29(8), 2439-2452 (2022). doi:10.1111/ene.15373
Background and purpose: Clinical trials in spinocerebellar ataxia type 3 (SCA3) will require biomarkers for use as outcome measures. Methods: To evaluate total tau (t-tau), glial fibrillary acidic protein (GFAP), ubiquitin carboxy-terminal hydrolase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15787867b0753f29d6406738bfb2c643
https://pubmed.ncbi.nlm.nih.gov/35478426
https://pubmed.ncbi.nlm.nih.gov/35478426
Autor:
Hector Garcia-Moreno, Julie Vallortigara, Mackenzie Wells, Susan Walther, Paola Giunti, David A. Lynch, Gilbert Thomas-Black, Andrada Dumitrascu, Hugh Montgomery, Barry Hunt, Julie Greenfield
Publikováno v:
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-10 (2022)
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-10 (2022)
Background The development of new therapies may rely on the conduct of human experimentation as well as later clinical trials of therapeutic interventions. Ethical considerations seek to protect the patient from risk but few have sought to ascertain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec51b1d461cec5855b1ba4db69f7cb1
https://doi.org/10.1186/s13023-021-02091-x
https://doi.org/10.1186/s13023-021-02091-x
Autor:
Rachel Brown, Gilbert Thomas-Black, Hector Garcia-Moreno, Miles Chapman, Michael Chou, Melanie Hart, Zofia Fleszar, Michael Zandi, Paola Giunti, Michael P Lunn
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 93:e2.173
Neurological syndromes associated with glutamic acid decarboxylase (GAD) antibodies provide a challenge in understanding disease pathogenesis, interpreting antibody results, and deciding manage- ment. We retrospectively reviewed 277 patients with pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cec2afe0ee4c9932889161a59e645df1
https://doi.org/10.1136/jnnp-2022-abn2.28
https://doi.org/10.1136/jnnp-2022-abn2.28
Autor:
Thomas Klopstock, M. Fichera, Francisco Javier Rodríguez de Rivera Garrido, Caterina Mariotti, Almut Turid Bischoff, Claudia Stendel, Christian Hohenfeld, Alexandra Durr, Anna Castaldo, Ilaria Giordano, Stefanie N. Hayer, Alessia Mongelli, Marie Lorraine Monin, Massimo Pandolfo, Kathrin Reetz, Katarina Manso, Gessica Vasco, Mar O'Callaghan, Nita Solanky, Matthias Amprosi, Claire Ewenczyk, Florian Holtbernd, Wolfgang Nachbauer, Sylvia Boesch, Enrico Bertini, Francesc Palau, Cinzia Gellera, Elisabetta Indelicato, Florentine Radelfahr, Imis Dogan, Marianthi Breza, Ludger Schöls, Christian Rummey, Michael H Parkinson, Andreas Eigentler, Jörg B. Schulz, Lorenzo Nanetti, Claire Didszun, Paola Giunti, Gilbert Thomas-Black, Nikolina Brcina, Marie Biet, Ralf-Dieter Hilgers, Robyn Labrum, Thomas Klockgether, Myriam Rai, Georgios Koutsis
Publikováno v:
The lancet / Neurology 20(5), 362-372 (2021). doi:10.1016/S1474-4422(21)00027-2
Summary Background The European Friedreich's Ataxia Consortium for Translational Studies (EFACTS) investigates the natural history of Friedreich's ataxia. We aimed to assess progression characteristics and to identify patient groups with differential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e639b3686431e2707c99907b08121ea
Autor:
Andrew Achilleos, Rachel McComb, Alistair Connell, Gilbert Thomas-Black, Joanna Sumpter, Julian Wijesuriya
Publikováno v:
The clinical teacher. 14(3)
Summary Background Junior doctors from varied medical specialties are increasingly undertaking placements in intensive care units (ICUs). They may have minimal previous experience in the provision of advanced organ support, yet may have high levels o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8ec91926335c18ddae916eb83470d3
https://pubmed.ncbi.nlm.nih.gov/27325356
https://pubmed.ncbi.nlm.nih.gov/27325356