Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gilbert Regnier"'
Autor:
Jean-Pierre Bizzari, Alain Dhainaut, Nicolas Guilbaud, Maryse Berlion, Suzy Cros, Theresa A. Dunn, Ghanem Atassi, Gilbert Regnier
Publikováno v:
Cancer Chemotherapy and Pharmacology. 30:491-494
S 9788, a new triazinoaminopiperidine derivative, was found to be a potent reversant of vincristine resistance in the in vivo murine leukemic P388/VCR model. In two treatment regimens (Q4D days 1, 5 and 9 and QD days 1-9), S 9788 enhanced the antitum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f11aa90667d93c5e8222ccb744925c
https://doi.org/10.1007/bf00685604
https://doi.org/10.1007/bf00685604
Autor:
Andre Tizot, Alain Dhainaut, Laurence Kraus-Berthier, Stéphane Léonce, Nicolas Guilbaud, Ghanem Atassi, Gilbert Regnier, Alain Pierré
Publikováno v:
Journal of medicinal chemistry. 39(20)
A series of 36 purine and purine analog derivatives have been synthesized and tested for their ability to modulate multidrug resistance in vitro (P388/VCR-20 and KB-A1 cells) and in vivo (P388/VCR leukemia). Compounds were compared to S9788, a triazi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12c873412532e619326cf3cd06aef59
https://pubmed.ncbi.nlm.nih.gov/8831775
https://pubmed.ncbi.nlm.nih.gov/8831775
Autor:
Albert Lenaers, Gilbert Regnier, Catherine Thollon, Frédéric Robin, Christine Cambarrat, Jean-Paul Vilaine, Claude Guillonneau, Jean-Pierre Iliou
Publikováno v:
European journal of pharmacology. 248(3)
Oxidative stress induced by reactive oxygen species is one aspect of the deleterious mechanisms involved in myocardial post-ischemic reperfusion injury. The antioxidant properties of the new molecule S12340 (8-[3-(3,5-diterbutyl-4-hydroxyphenyl-thio)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4823718c5c9e324d118b6163134aa14
https://pubmed.ncbi.nlm.nih.gov/8293791
https://pubmed.ncbi.nlm.nih.gov/8293791
Autor:
Alain Dhainaut, Gilbert Regnier, Jean Francois Prost, Stéphane Léonce, Ghanem Atassi, Laurence Kraus-Berthier, Alain Pierré
Publikováno v:
Journal of medicinal chemistry. 35(13)
A series of 70 triazine derivatives have been synthesized and tested for their capacity to modulate multidrug resistance (MDR) in DC-3F/AD and KB-A1 tumor cells in vitro, in comparison with verapamil (VRP), a calcium channel antagonist currently used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25af248fb4b814f3d809332d77400cfc
https://pubmed.ncbi.nlm.nih.gov/1352353
https://pubmed.ncbi.nlm.nih.gov/1352353
Autor:
Françoise P Tisserand, Claude Guillonneau, Sophie M Holstorp, Guy Saint-Romas, Jacques Duhault, Gilbert Regnier
Publikováno v:
European Journal of Medicinal Chemistry. 22:243-250
Twenty eight new derivatives of 8-aminoalkyl substituted xanthine have been synthesized. They all have demonstrated a potent anti-bronchoconstrictive effect in the guinea pig and some of them have a very long duration of action (> 48 h). Among them,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d22588b66d7290937388d0fb217d5568
https://doi.org/10.1016/0223-5234(87)90056-0
https://doi.org/10.1016/0223-5234(87)90056-0
Publikováno v:
Journal of Medicinal Chemistry. 11:1151-1155
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd5a12f215e7ce3ec23ae6fd9619510
https://doi.org/10.1021/jm00312a010
https://doi.org/10.1021/jm00312a010
Autor:
Jacques Duhault, Gilbert Regnier, Sophie M Holstorp, Claude Guillonneau, Guy Saint-Romas, Françoise P Tisserand
Publikováno v:
ChemInform. 18
Twenty eight new derivatives of 8-aminoalkyl substituted xanthine have been synthesized. They all have demonstrated a potent anti-bronchoconstrictive effect in the guinea pig and some of them have a very long duration of action (> 48 h). Among them,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75e0b6f6317c2dbc4faa8075027af8f0
https://doi.org/10.1002/chin.198744225
https://doi.org/10.1002/chin.198744225
Publikováno v:
Chemischer Informationsdienst. Organische Chemie. 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e21143123e549ee89d2c35a6cdf487d
https://doi.org/10.1002/chin.197117116
https://doi.org/10.1002/chin.197117116