Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Gilbert O'Young"'
Autor:
Marcus M. Fischer, V. Pete Yeung, Fiore Cattaruzza, Rajaa Hussein, Wan-Ching Yen, Christopher Murriel, James W. Evans, Gilbert O’Young, Alayne L. Brunner, Min Wang, Jennifer Cain, Belinda Cancilla, Ann Kapoun, Timothy Hoey
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Activating mutations in the Wnt pathway are a characteristic feature of colorectal cancer (CRC). The R-spondin (RSPO) family is a group of secreted proteins that enhance Wnt signaling and RSPO2 and RSPO3 gene fusions have been reported in CR
Externí odkaz:
https://doaj.org/article/97a62eb300e14b3a9c293d6e18060cfa
Autor:
Timothy Hoey, Austin Gurney, John Lewicki, Gilbert O'Young, Min Wang, Ann M. Kapoun, Wan-Ching Yen, Marcus Fischer
Supplementary Table 1, Materials and Methods, Figure Legends 1-4 from Anti-DLL4 Inhibits Growth and Reduces Tumor-Initiating Cell Frequency in Colorectal Tumors with Oncogenic KRAS Mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7506435bc1d5a29a73cd03b7586355
https://doi.org/10.1158/0008-5472.22389633.v1
https://doi.org/10.1158/0008-5472.22389633.v1
Autor:
Austin Gurney, Timothy Hoey, John Lewicki, Ann M. Kapoun, Min Wang, Gilbert O'Young, Belinda Cancilla, Pete Yeung, Wan-Ching Yen, Michelle Stroud, Andrew Lam, May Ji, Jie Wei, Jalpa Shah, Marcus M. Fischer, Shirley Ma, Cristina Dee-Hoskins, Jennifer Cain, Chris Bond, Fumiko Axelrod, Janak Raval, Cecile Chartier
Supplemental figure legends also include brief methods where appropriate.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c92ef1c6e992c263c2057d6a7459f78
https://doi.org/10.1158/0008-5472.22410083.v1
https://doi.org/10.1158/0008-5472.22410083.v1
Autor:
Timothy Hoey, Austin Gurney, John Lewicki, Gilbert O'Young, Min Wang, Ann M. Kapoun, Wan-Ching Yen, Marcus Fischer
Supplementary Figure 1 from Anti-DLL4 Inhibits Growth and Reduces Tumor-Initiating Cell Frequency in Colorectal Tumors with Oncogenic KRAS Mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6553367358d8b1c6a123232f5e2e1ae
https://doi.org/10.1158/0008-5472.22389645
https://doi.org/10.1158/0008-5472.22389645
Autor:
Timothy Hoey, Austin Gurney, John Lewicki, Gilbert O'Young, Min Wang, Ann M. Kapoun, Wan-Ching Yen, Marcus Fischer
Supplementary Figure 3 from Anti-DLL4 Inhibits Growth and Reduces Tumor-Initiating Cell Frequency in Colorectal Tumors with Oncogenic KRAS Mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab124a6e63ad8292ad3f6770a7e6a64a
https://doi.org/10.1158/0008-5472.22389639.v1
https://doi.org/10.1158/0008-5472.22389639.v1
Autor:
Austin Gurney, Timothy Hoey, John Lewicki, Ann M. Kapoun, Min Wang, Gilbert O'Young, Belinda Cancilla, Pete Yeung, Wan-Ching Yen, Michelle Stroud, Andrew Lam, May Ji, Jie Wei, Jalpa Shah, Marcus M. Fischer, Shirley Ma, Cristina Dee-Hoskins, Jennifer Cain, Chris Bond, Fumiko Axelrod, Janak Raval, Cecile Chartier
Deregulation of the β-catenin signaling has long been associated with cancer. Intracellular components of this pathway, including axin, APC, and β-catenin, are frequently mutated in a range of human tumors, but the contribution of specific extracel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a2dd884372d990c2aeb1d5180b91e4
https://doi.org/10.1158/0008-5472.c.6507911
https://doi.org/10.1158/0008-5472.c.6507911
Autor:
Austin Gurney, Timothy Hoey, John Lewicki, Ann M. Kapoun, Min Wang, Gilbert O'Young, Belinda Cancilla, Pete Yeung, Wan-Ching Yen, Michelle Stroud, Andrew Lam, May Ji, Jie Wei, Jalpa Shah, Marcus M. Fischer, Shirley Ma, Cristina Dee-Hoskins, Jennifer Cain, Chris Bond, Fumiko Axelrod, Janak Raval, Cecile Chartier
Supplemental Tables include a list and brief description of xenograft models used in the study, the RSPO1-4 gene expression profile and beta-catenin activation status of all xenograft models, and the microarray analysis for 4 CRC xenograft models aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c673aa921f31eb42807e17eb99f932
https://doi.org/10.1158/0008-5472.22410080.v1
https://doi.org/10.1158/0008-5472.22410080.v1
Autor:
Timothy Hoey, Austin Gurney, John Lewicki, Gilbert O'Young, Min Wang, Ann M. Kapoun, Wan-Ching Yen, Marcus Fischer
Supplementary Figure 2 from Anti-DLL4 Inhibits Growth and Reduces Tumor-Initiating Cell Frequency in Colorectal Tumors with Oncogenic KRAS Mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c37103622f3fc661886e2b5b401ebe
https://doi.org/10.1158/0008-5472.22389642
https://doi.org/10.1158/0008-5472.22389642
Autor:
Timothy Hoey, Austin Gurney, John Lewicki, Gilbert O'Young, Min Wang, Ann M. Kapoun, Wan-Ching Yen, Marcus Fischer
Supplementary Figure 4 from Anti-DLL4 Inhibits Growth and Reduces Tumor-Initiating Cell Frequency in Colorectal Tumors with Oncogenic KRAS Mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a44c9d4e8cb25c20bd398535a3b263
https://doi.org/10.1158/0008-5472.22389636.v1
https://doi.org/10.1158/0008-5472.22389636.v1
Autor:
Austin Gurney, Timothy Hoey, John Lewicki, Ann M. Kapoun, Min Wang, Gilbert O'Young, Belinda Cancilla, Pete Yeung, Wan-Ching Yen, Michelle Stroud, Andrew Lam, May Ji, Jie Wei, Jalpa Shah, Marcus M. Fischer, Shirley Ma, Cristina Dee-Hoskins, Jennifer Cain, Chris Bond, Fumiko Axelrod, Janak Raval, Cecile Chartier
Supplemental figures include the RSPO gene expression analysis for CRC models, the in vitro testing of anti-RSPO antibodies on RSPO-negative tumors, the IHC analysis of anti-RSPO3+chemo-treated ovarian tumors, the LGR, ZNRF3, and RNF43 gene expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19afe2511ee33ae67efef1d503d78862
https://doi.org/10.1158/0008-5472.22410086.v1
https://doi.org/10.1158/0008-5472.22410086.v1