Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Gilbert M. Eisner"'
Publikováno v:
Hypertension. 67:1056-1063
Hypertension is present in about 40% of the world's population and is responsible for 12.8% of total deaths (1). In the USA, hypertension affects 32% (2011 to 2012) of the middle-age (40-59 years) adult population and is responsible for 35.6% of tota
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48eb41158a38c75c277c368895a4199f
https://doi.org/10.1161/hypertensionaha.115.06424
https://doi.org/10.1161/hypertensionaha.115.06424
Autor:
Xiaoyan Wang, Shi-You Chen, Van Anthony M. Villar, John E. Jones, Pedro A. Jose, Laureano D. Asico, Zheng Wang, Gilbert M. Eisner, Matthew R. Weir, Robin A. Felder, Hironobu Sanada, Prasad Konkalmatt, Ines Armando, Chunyu Zeng, Yu Yang
Publikováno v:
Hypertension. 67:325-334
The influence of a single gene on the pathogenesis of essential hypertension may be difficult to ascertain, unless the gene interacts with other genes that are germane to blood pressure regulation. G-protein–coupled receptor kinase type 4 ( GRK4 )
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7d1c259b0eb4bbaca475817785d18ad
https://doi.org/10.1161/hypertensionaha.115.05962
https://doi.org/10.1161/hypertensionaha.115.05962
Autor:
Aruna Natarajan, John C. Pezzullo, Shaunagh Browning, Gilbert M. Eisner, Robert M. Carey, Mustafa I. Dajani, Pedro A. Jose, Ines Armando, Lauren Rhee
Publikováno v:
Journal of the American Society of Nephrology. 27:265-279
The renin-angiotensin-aldosterone (RAAS) and renal dopaminergic systems interact to maintain sodium balance. High NaCl intake increases renal synthesis of dopamine and dopaminergic receptor activity, decreasing epithelial sodium transport, whereas so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89fbed7cc36625b1e26f98d38149d583
https://doi.org/10.1681/asn.2014100958
https://doi.org/10.1681/asn.2014100958
Autor:
Scott M. Williams, Hironobu Sanada, Marquitta J. White, Robin A. Felder, Junichi Yatabe, Jacquelaine Bartlett, Pedro A. Jose, Ines Armando, Minoru Yoneda, Lindsay N. Gordon, Gilbert M. Eisner
Publikováno v:
The Pharmacogenomics Journal. 16:3-9
Non-synonymous GRK4 variants, R65L, A142V and A486V, are associated with essential hypertension in diverse populations. This study replicated the association of GRK4 variants, including GRK4(142V), with human essential hypertension in a Japanese popu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b184bf6f0034da03ac1afb4207d5db2
https://doi.org/10.1038/tpj.2015.6
https://doi.org/10.1038/tpj.2015.6
Autor:
Hongmei Ren, Lin Zhou, Caiyu Chen, Jin Cai, Yu Han, Chunyu Zeng, Duofen He, Pedro A. Jose, Laureano D. Asico, Gilbert M. Eisner
Publikováno v:
Journal of Molecular Cell Biology. 5:227-238
Extracellular vesicles (EVs) carry signals within or at their limiting membranes, providing a mechanism by which cells can exchange more complex information than what was previously thought. In addition to mRNAs and microRNAs, there are DNA fragments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75228ddf1bf00b46a96b04478a8ed1c8
https://doi.org/10.1093/jmcb/mjt011
https://doi.org/10.1093/jmcb/mjt011
Autor:
John E. Jones, Peiying Yu, Van Anthony M. Villar, Gilbert M. Eisner, Laureano D. Asico, Pedro A. Jose, Hewang Li, Yu Yang, Edward J. Weinman, Quansheng Lu
Publikováno v:
Hypertension Research. 36:684-690
D5 dopamine receptor (D5R) knock-out mice (D5(-/-)) have a higher blood pressure (BP) and higher reactive oxygen species (ROS) production than their D5R wild-type littermates (D5(+/+)). We tested the hypothesis that the high BP and increased ROS prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3649339b742cc02ab5286ddb63e80c4a
https://doi.org/10.1038/hr.2013.9
https://doi.org/10.1038/hr.2013.9
Autor:
Hirohide Yokokawa, Tsuyoshi Watanabe, Robin A. Felder, Pedro A. Jose, Hironobu Sanada, Gilbert M. Eisner, Aya Goto, Seiji Yasumura
Publikováno v:
American Journal of Hypertension. 23:1299-1305
Background The relationship between achieving target blood pressures and medication modification among hypertensive patients in Japan is relatively unknown. We examined the incidence of prescription changes and how the prescription changes influence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eaab7c99eb7f3db7a098ced86c19ec8
https://doi.org/10.1038/ajh.2010.175
https://doi.org/10.1038/ajh.2010.175
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1802:1259-1267
Complex interactions between genes and environment result in a sodium-induced elevation in blood pressure (salt sensitivity) and/or hypertension that lead to significant morbidity and mortality affecting up to 25% of the middle-aged adult population
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331d1ee712df3f13b163ff833ae8a27c
https://doi.org/10.1016/j.bbadis.2010.02.004
https://doi.org/10.1016/j.bbadis.2010.02.004
Autor:
Ines Armando, Xiaoyan Wang, Zhiwei Yang, Gilbert M. Eisner, Pedro A. Jose, David R. Sibley, John E. Jones, Crisanto S. Escano, Yingjin Luo, Laureano D. Asico, Hewang Li, Quansheng Lu
Publikováno v:
Hypertension. 55:1431-1437
D 5 dopamine receptor (D 5 R)-deficient (D 5 −/− ) mice have hypertension that is aggravated by an increase in sodium intake. The present experiments were designed to test the hypothesis that a dysregulation of renal sodium transporters is relate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17deb807c267117da47b8a290a16ab50
https://doi.org/10.1161/hypertensionaha.109.148643
https://doi.org/10.1161/hypertensionaha.109.148643
Autor:
Zhiwei, Yang, Xin, Huang, Hong, Jiang, Yanrong, Zhang, Hongxia, Liu, Chuan, Qin, Gilbert M, Eisner, Pedro A, Jose, Pedro, Jose, Lenhard, Rudolph, Zhenyu, Ju
Publikováno v:
Hypertension. 53:639-645
Aging is a major risk factor for hypertension and cardiovascular disease. Accumulating evidence suggests that telomere length is a marker for biological aging of the cardiovascular system. Telomere length is determined by genetic and environmental fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362a3de5d85c52df3e40654c59043476
https://doi.org/10.1161/hypertensionaha.108.123752
https://doi.org/10.1161/hypertensionaha.108.123752