Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Gilbert H, Smith"'
Supplementary Figures 1-3, Tables 1-2 from Reprogramming Human Cancer Cells in the Mouse Mammary Gland
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad5604dff36985fa3d1112e482b3161
https://doi.org/10.1158/0008-5472.22383426
https://doi.org/10.1158/0008-5472.22383426
The tissue microenvironment directs stem/progenitor cell behavior. Cancer cells are also influenced by the microenvironment. It has been shown that, when placed into blastocysts, cancer cells respond to embryonic cues and differentiate according to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::357c47db70dec9db052e5949710fc16d
https://doi.org/10.1158/0008-5472.c.6500535
https://doi.org/10.1158/0008-5472.c.6500535
Autor:
Sonia M. Rosenfield, Gilbert H. Smith
Publikováno v:
Cells, Vol 2, Iss 1, Pp 43-56 (2013)
Tumorigenesis is often described as a result of accumulated mutations that lead to growth advantage and clonal expansion of mutated cells. There is evidence in the literature that cancer cells are influenced by the microenvironment. Our previous stud
Externí odkaz:
https://doaj.org/article/44a4da24db414e199d35e5b17e2c8d3e
Autor:
Thomas J. Meyer, Anastasia Frank-Kamenetskii, Meredith Reeves, Lauren E. Ragle, Corinne A. Boulanger, Brian W. Booth, H. Caroline Jordan, Julia M. Mook, Gilbert H. Smith
Publikováno v:
Oncotarget
The influence of breast cancer cells on normal cells of the microenvironment, such as fibroblasts and macrophages, has been heavily studied but the influence of normal epithelial cells on breast cancer cells has not. Here using in vivo and in vitro m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b469d883ca8613cdfb4e694599f988e
https://doi.org/10.18632/oncotarget.27679
https://doi.org/10.18632/oncotarget.27679
Publikováno v:
Oncotarget
One major foundation of cancer etiology is the process of clonal expansion. The mechanisms underlying the complex process of a single cell leading to a clonal dominant tumor, are poorly understood. Our study aims to analyze mitochondrial DNA (mtDNA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3a6f72b6886a7ae48bd74070cec90c
https://doi.org/10.18632/oncotarget.27429
https://doi.org/10.18632/oncotarget.27429
Publikováno v:
Oncotarget
Microarray technologies were used to analyze transcriptomes from Comma-Dβ and clonal derivatives, SP3 (Lobule-competent) and NSP2 (Lobule-incompetent), during different mouse mammary growth phases: in-vitro, in-vivo 5-weeks, and in-vivo 12-weeks. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166b29065cd45d6615931168d19e3d21
http://europepmc.org/articles/PMC6481333
http://europepmc.org/articles/PMC6481333
Autor:
Corinne A Boulanger, Robert D Bruno, David L Mack, Monica Gonzales, Nadia P Castro, David S Salomon, Gilbert H Smith
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62019 (2013)
Experiments were conducted to redirect mouse Embryonic Stem (ES) cells from a tumorigenic phenotype to a normal mammary epithelial phenotype in vivo. Mixing LacZ-labeled ES cells with normal mouse mammary epithelial cells at ratios of 1:5 and 1:50 in
Externí odkaz:
https://doaj.org/article/42866e0bc41b4b1ba0cfd1a5bbfe8ba5
Autor:
Ahmed Raafat, Luigi Strizzi, Karim Lashin, Erika Ginsburg, David McCurdy, David Salomon, Gilbert H Smith, Daniel Medina, Robert Callahan
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43624 (2012)
The FVB/N mouse strain is extensively used in the development of animal models for breast cancer research. Recently it has been reported that the aging FVB/N mice develop spontaneous mammary lesions and tumors accompanied with abnormalities in the pi
Externí odkaz:
https://doaj.org/article/d9c4673504c44773868a7a1a1aa3da53
Autor:
Karen M Bussard, Gilbert H Smith
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49221 (2012)
Breast cancer is the second leading cause of cancer deaths in the United States. At present, the etiology of breast cancer is unknown; however the possibility of a distinct cell of origin, i.e. a cancer stem cell, is a heavily investigated area of re
Externí odkaz:
https://doaj.org/article/03eb3751f303440a8df07b7dd4d1c878
Autor:
Karen M. Bussard, Gilbert H. Smith
Publikováno v:
International Journal of Cell Biology, Vol 2011 (2011)
The mammary gland is a unique organ that continually undergoes postnatal developmental changes. In mice, the mammary gland is formed via signals from terminal end buds, which direct ductal growth and elongation. Intriguingly, it is likely that the en
Externí odkaz:
https://doaj.org/article/fe0f0b83f47940b8b16d223273d6a5f8