Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Gilbert Gorr"'
Autor:
Xiangmin Lv, Jesse Martin, Heather Hoover, Bishnu Joshi, Margaret Wilkens, David A. Ullisch, Thomas Leibold, John S. Juchum, Sanket Revadkar, Barbara Kalinovska, Justin Keith, Adam Truby, Gui Liu, Elaine Sun, John Haserick, Jon DeGnore, Joseph Conolly, Adrian V.S. Hill, John Baldoni, Charlotte Kensil, Dan Levey, Alexandra J. Spencer, Gilbert Gorr, Mark Findeis, Antoine Tanne
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109006- (2024)
Summary: Many vaccines, including those using recombinant antigen subunits, rely on adjuvant(s) to enhance the efficacy of the host immune responses. Among the few adjuvants clinically approved, QS-21, a saponin-based immunomodulatory molecule isolat
Externí odkaz:
https://doaj.org/article/4ce190e0d41a4a90adc8bb0b7532bfc5
Autor:
Gabriel Corkidi, Rainer Krull, Dominik Sieblitz, Kai Schütte, Jaime A. Pimentel, Christoph Wittmann, Annika Schulz, Gilbert Gorr, Matthias Pump, Thomas Wucherpfennig
Publikováno v:
Bioprocess and Biosystems Engineering. 37:1799-1808
For the commercially established process of paclitaxel production with Taxus chinensis plant cell culture, the size of plant cell aggregates and phenotypic changes in coloration during cultivation have long been acknowledged as intangible parameters.
Autor:
Juliana Parsons, Claudia K. Arrenberg, Friedrich Altmann, Anna Koprivova, Gilbert Gorr, Ralf Reski, Christian Stemmer, Anna K. Beike, Eva L. Decker
Publikováno v:
Plant Biotechnology Journal. 10:851-861
Summary Protein therapeutics represent one of the most increasing areas in the pharmaceutical indus- try. Plants gain acceptance as attractive alternatives for high-quality and economical protein production. However, as the majority of biopharmaceuti
Autor:
Heike Launhardt, Eric R. Sjoberg, Marta Rodriguez-Franco, Friedrich Altmann, Gilbert Gorr, Andreas Weise, Wolfgang Bäumer, Manfred Kietzmann
Publikováno v:
Plant Biotechnology Journal. 5:389-401
The highly glycosylated peptide hormone erythropoietin (EPO) plays a key role in the regulation of erythrocyte maturation. Currently, marketed EPO is produced by recombinant technology in mammalian cell cultures. The complementary DNA (cDNA) for huma
Autor:
Gilbert Gorr, Wolfgang H. Jost
Publikováno v:
BioProcessing Journal. 5:30-34
Autor:
Birgit Berg, Armin Baur, Gilbert Gorr, Andreas Weise, Manfred Kietzmann, Helene Rolli, Rasmus Luethje, Ralf Reski, Michael C. Braun, Franz Kaufmann, Wolfgang Baeumer
Publikováno v:
Journal of Biotechnology. 119:332-342
Plant expression systems offer a valuable alternative to traditional systems for the production of recombinant biopharmaceuticals. A highly efficient polyethyleneglycol (PEG)-mediated transient expression system for secreted recombinant proteins in p
Autor:
Eva L. Decker, C. M. Huether, O. Lienhart, Christian Stemmer, Gilbert Gorr, Ralf Reski, Armin Baur
Publikováno v:
Plant Biology. 7:292-299
The commercial production of complex pharmaceutical proteins from human origin in plants is currently limited through differences in protein N-glycosylation pattern between plants and humans. On the one hand, plant-specific alpha(1,3)-fucose and beta
Publikováno v:
Plant Biotechnology Journal. 3:331-340
The production of pharmaceutical proteins in plants provides a valuable alternative to other traditional eukaryotic expression systems from economic and safety perspectives. The moss Physcomitrella patens allows the expression and secretion of comple
Publikováno v:
Current Genetics. 47:111-120
The moss Physcomitrella patens is an excellent tool to study plant gene-function relationships due to its high rate of homologous recombination (HR). It has also been shown to be very useful in the production of recombinant proteins which are secrete
Autor:
Gilbert Gorr, Eva L. Decker, Stanislav Kopriva, Ralf Reski, Friedrich Altmann, Anna Koprivova
Publikováno v:
Plant Biology. 5:582-591
Allergenicity of plant glycoproteins in humans may prevent the use of plants as production factories for pharmaceutically important proteins. The major difference between plant and mammalian N-glycans is the presence of xylosyl and α1,3-fucosyl resi