Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gilbert E. Bautista"'
Autor:
Peter Jorth, Kathryn McLean, Anina Ratjen, Patrick R. Secor, Gilbert E. Bautista, Sumedha Ravishankar, Amir Rezayat, Jayanthi Garudathri, Joe J. Harrison, Rachel A. Harwood, Kelsi Penewit, Adam Waalkes, Pradeep K. Singh, Stephen J. Salipante
Publikováno v:
mBio, Vol 8, Iss 5 (2017)
ABSTRACT While much attention has been focused on acquired antibiotic resistance genes, chromosomal mutations may be most important in chronic infections where isolated, persistently infecting lineages experience repeated antibiotic exposure. Here, w
Externí odkaz:
https://doaj.org/article/3789d0f4355743ab928140bb13ba807a
Autor:
Sarah J Morgan, Soyeon I Lippman, Gilbert E Bautista, Joe J Harrison, Christopher L Harding, Larry A Gallagher, Ann-Chee Cheng, Richard Siehnel, Sumedha Ravishankar, Marcia L Usui, John E Olerud, Philip Fleckman, Randall D Wolcott, Colin Manoil, Pradeep K Singh
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007511 (2019)
While much is known about acute infection pathogenesis, the understanding of chronic infections has lagged. Here we sought to identify the genes and functions that mediate fitness of the pathogen Pseudomonas aeruginosa in chronic wound infections, an
Externí odkaz:
https://doaj.org/article/04a0e9429ad1465aa981669a15696103
Autor:
Elizabeth A. Holmes, Gilbert E. Bautista, Dustin R. Long, Alexander L. Greninger, Pradeep K. Singh, Vikas Peddu, Ryan C. Shean, Stephen J. Salipante, Sara L. Rassoulian Barrett, Sumedha Ravishankar, Brad T. Cookson
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-6 (2020)
Scientific Reports
Scientific Reports
Diagnostically informative microbial cell-free DNA (cfDNA) can be detected from blood plasma during fulminant infections such as sepsis. However, the potential for DNA from airway pathogens to enter the circulation of cystic fibrosis (CF) patients du
Autor:
Mitchell J. Brittnacher, John J. LiPuma, Alexander Eng, Anh T. Vo, Luke R Hoffman, Sumedha Ravishankar, Gilbert E. Bautista, Richard Simon, Daniel J. Wolter, Elhanan Borenstein, Cheryl Majors, Eli J. Weiss, Hillary S. Hayden, Maria T. Nelson, Sharon McNamara, Laura Nay, Samuel I. Miller, Marcella Blackledge, Anina Ratjen
Publikováno v:
Thorax
RationaleThe most common antibiotic used to treat people with cystic fibrosis (PWCF) is inhaled tobramycin, administered as maintenance therapy for chronic Pseudomonas aeruginosa lung infections. While the effects of inhaled tobramycin on P. aerugino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a06f074834457c24a4b52f865d2f1cbd
https://europepmc.org/articles/PMC7875198/
https://europepmc.org/articles/PMC7875198/
Autor:
Angus Angermeyer, Xia Wu, Corinne L. Fligner, Benjamin J. Staudinger, Jayanthi Garudathri, Peter Jorth, Hillary S. Hayden, John E. Mittler, Pradeep K. Singh, Matthew C. Radey, William R. Berrington, Timothy L. Yahr, Mitchell J. Brittnacher, Colin Manoil, Gilbert E. Bautista, Jacob O. Kitzman, Moira L. Aitken, Amanda F. Goddard, James E. Bruce, Amir Rezayat, Katherine B. Hisert, Jay Shendure, Christopher L. Harding, Chunxiang Zheng
Publikováno v:
Cell Host & Microbe. 18:307-319
SummaryBacterial lineages that chronically infect cystic fibrosis (CF) patients genetically diversify during infection. However, the mechanisms driving diversification are unknown. By dissecting ten CF lung pairs and studying ∼12,000 regional isola