Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Gilbert Croteau"'
Autor:
Gilbert Croteau, Jean-Francois Poulin, Salim Ahmed Khan, Marc Mansour, Geneviève Lévesque, Claire Landry, Dominic Gagnon, Yoav Peretz, Dominike Sauvé, Mohan Karkada, Valérie Hébert, Bader Yassine Diab, Karyne Savard, Nathalie Saha
Publikováno v:
Cancer Research. 74:CT411-CT411
Survivin is a member of the inhibitor of apoptosis protein family and its over-expression has been reported in many cancer types such as melanoma, colon, brain, breast, and ovarian cancers making it a promising target for immunotherapy. DPX-Survivac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22745104f862e7f5532020845f5621ab
https://doi.org/10.1158/1538-7445.am2014-ct411
https://doi.org/10.1158/1538-7445.am2014-ct411
Autor:
Louis Plamondon, William Paris, Francine Liard, Daniel Lamarre, Paul C. Anderson, Pierre L. Beaulieu, Gilbert Croteau, Dominik Wernic, Francois Soucy, Liang Tong, Vida Gorys, Susan Pav, Diane Thibeault, Dale R. Cameron, Chantal Grand-Maître, Christiane Yoakim
Publikováno v:
Journal of medicinal chemistry. 43(6)
Starting from palinavir (1), our lead HIV protease inhibitor, we have discovered a new series of truncated analogues in which the P(3)-P(2) quinaldic-valine portion of 1 was replaced by 2', 6'-dimethylphenoxyacetyl. With EC(50)'s in the 1-2 nM range,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468c8b2501190b16291ce68d35e4c559
https://pubmed.ncbi.nlm.nih.gov/10737742
https://pubmed.ncbi.nlm.nih.gov/10737742