Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gilbert C. Schmidt"'
Publikováno v:
Journal of Pharmaceutical Sciences. 57:1357-1360
Using a modification of the Robinson condensation, citric-3-14C acid, citric-2,4-14C acid, and citric-2,3,4-14C acid were converted into correspondingly labeled tropine and atropine. The specific activities of the products varied from 0.62 to 1.0 dep
Publikováno v:
Journal of Pharmaceutical Sciences. 52:468-472
A modification of Riegler's nitrite test, employing betanaphthol, sodium nitrite, and naphthylamine or sulfanilamide, has been adapted for location of organic acids on paper chromatograms. Most of the twelve acids tested are detectable at a level of
Publikováno v:
Journal of Pharmaceutical Sciences. 57:443-446
Using a previously described modification of the Robinson condensation, N -methyl- 14 C-tropine, specific gravity 1 mc./mmole, was synthesized from methylamine- 14 C-HCl in 65 percent of theoretical yield. Subsequent esterification with unlabeled tro
Publikováno v:
Journal of Pharmaceutical Sciences. 56:215-221
Yields for each step in the esterification of tropine and tropic acid have been determined with micro and semimicro quantities of reactants. In a similar way, the Robinson condensation has been studied. Data are compared with the findings of other in
Publikováno v:
Journal of pharmaceutical sciences. 56(11)
Prototype methods for the synthesis of tropines- 14 C and tropine-labeled atropines are described. These compounds and the requisite labeled intermediates may be synthesized from arabinose-5- 14 C or arabinose-UL- 14 C. Yields for each step in the co
Publikováno v:
Journal of pharmaceutical sciences. 55(8)
Pooled rabbit serum containing atropinesterase, pooled rabbit serum lacking atropinesterase, and pooled goat serum were tested for their effect on some pharmacological parameters of atropine and related compounds. Pooled goat serum was found to conta
Publikováno v:
The Journal of pediatrics. 60
Summary Certain samples of antipertussis serum (rabbit) exerted a favorable effect in atropine-poisoned children, while other samples are inactive. No relationship between clinical effectiveness and atropinesterase content has been established althou
Publikováno v:
Journal of pharmaceutical sciences. 55(9)
Three strains of Aspergillus versicolor were isolated from soil, obtained in pure culture, and grown with atropine sulfate as the sole source of carbon and nitrogen. Optimum growth was obtained at 25°, when cultures were aerated by continual shaking