Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Gilbert, Weidinger"'
Autor:
Chiara Bongiovanni, Hanna Bueno-Levy, Denise Posadas Pena, Irene Del Bono, Carmen Miano, Stefano Boriati, Silvia Da Pra, Francesca Sacchi, Simone Redaelli, Max Bergen, Donatella Romaniello, Francesca Pontis, Riccardo Tassinari, Laura Kellerer, Ilaria Petraroia, Martina Mazzeschi, Mattia Lauriola, Carlo Ventura, Stephan Heermann, Gilbert Weidinger, Eldad Tzahor, Gabriele D’Uva
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114162- (2024)
Summary: Zebrafish have a lifelong cardiac regenerative ability after damage, whereas mammals lose this capacity during early postnatal development. This study investigated whether the declining expression of growth factors during postnatal mammalian
Externí odkaz:
https://doaj.org/article/5573ad2f6dc842149bf5004bdff0af4a
Autor:
Ivonne Sehring, Gilbert Weidinger
Publikováno v:
Cold Spring Harbor perspectives in biology. 14(7)
The zebrafish caudal fin has become a popular model to study cellular and molecular mechanisms of regeneration due to its high regenerative capacity, accessibility for experimental manipulations, and relatively simple anatomy. The formation of a rege
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::065fe64e5fb120fe0d6882545cd4d029
https://pubmed.ncbi.nlm.nih.gov/34649924
https://pubmed.ncbi.nlm.nih.gov/34649924
Autor:
Mirja Harms, Monica M.W. Habib, Simona Nemska, Antonella Nicolò, Andrea Gilg, Nico Preising, Pandian Sokkar, Sara Carmignani, Martina Raasholm, Gilbert Weidinger, Gönül Kizilsavas, Manfred Wagner, Ludger Ständker, Ashraf H. Abadi, Hassan Jumaa, Frank Kirchhoff, Nelly Frossard, Elsa Sanchez-Garcia, Jan Münch
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2694-2708 (2021)
Aberrant CXCR4/CXCL12 signaling is involved in many pathophysiological processes such as cancer and inflammatory diseases. A natural fragment of serum albumin, named EPI-X4, has previously been identified as endogenous peptide antagonist and inverse
Externí odkaz:
https://doaj.org/article/877b759cf88f4e9a87e25611fe551bb2
Autor:
Pandian Sokkar, Mirja Harms, Christina Stürzel, Andrea Gilg, Gönül Kizilsavas, Martina Raasholm, Nico Preising, Manfred Wagner, Frank Kirchhoff, Ludger Ständker, Gilbert Weidinger, Benjamin Mayer, Jan Münch, Elsa Sanchez-Garcia
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Combining molecular modeling and in vitro bioassays, Sokkar et al. provide an understanding of how EPI-X4, an endogenous peptide antagonist, interacts with its receptor CXCR4. With computational model, validated by mutagenesis studies, they design a
Externí odkaz:
https://doaj.org/article/f993d3d26776456ebe0fc89bf8e4a5df
Autor:
Ivonne Sehring, Hossein Falah Mohammadi, Melanie Haffner-Luntzer, Anita Ignatius, Markus Huber-Lang, Gilbert Weidinger
Publikováno v:
eLife, Vol 11 (2022)
Successful regeneration requires the coordinated execution of multiple cellular responses to injury. In amputated zebrafish fins, mature osteoblasts dedifferentiate, migrate towards the injury, and form proliferative osteogenic blastema cells. We sho
Externí odkaz:
https://doaj.org/article/9e1040d4d88647828c358d647d17b21d
Autor:
Anja Bühler, Bernd M. Gahr, Deung-Dae Park, Alberto Bertozzi, Alena Boos, Mohankrishna Dalvoy, Alexander Pott, Franz Oswald, Rhett A. Kovall, Bernhard Kühn, Gilbert Weidinger, Wolfgang Rottbauer, Steffen Just
Publikováno v:
PLoS Genetics, Vol 17, Iss 11 (2021)
In contrast to mammals, the zebrafish maintains its cardiomyocyte proliferation capacity throughout adulthood. However, neither the molecular mechanisms that orchestrate the proliferation of cardiomyocytes during developmental heart growth nor in the
Externí odkaz:
https://doaj.org/article/96001da5e7a44875bca991c5371b18cb
Autor:
Matthias Reisser, Anja Palmer, Achim P. Popp, Christopher Jahn, Gilbert Weidinger, J. Christof M. Gebhardt
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Zygotic genome activation (ZGA), the onset of transcription after initial quiescence, is a major developmental step in many species. Here authors use single molecule tracking in live developing zebrafish embryos to show that increased transcription f
Externí odkaz:
https://doaj.org/article/aa3a72768df54453a0f079cb56f836f5
Autor:
Ivonne Sehring, Gilbert Weidinger
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 101031- (2021)
Externí odkaz:
https://doaj.org/article/e68d5cbd4e8f4a38ad88bdb216f831d1
Autor:
Reiner Noschka, Fabian Gerbl, Florian Löffler, Jan Kubis, Armando A. Rodríguez, Daniel Mayer, Mark Grieshober, Armin Holch, Martina Raasholm, Wolf-Georg Forssmann, Barbara Spellerberg, Sebastian Wiese, Gilbert Weidinger, Ludger Ständker, Steffen Stenger
Publikováno v:
Frontiers in Microbiology, Vol 11 (2021)
Tuberculosis is a highly prevalent infectious disease with more than 1.5 million fatalities each year. Antibiotic treatment is available, but intolerable side effects and an increasing rate of drug-resistant strains of Mycobacterium tuberculosis (Mtb
Externí odkaz:
https://doaj.org/article/4c71e6dd4c7540e7a3b18b1486d5c991
Autor:
Hessel Honkoop, Dennis EM de Bakker, Alla Aharonov, Fabian Kruse, Avraham Shakked, Phong D Nguyen, Cecilia de Heus, Laurence Garric, Mauro J Muraro, Adam Shoffner, Federico Tessadori, Joshua Craiger Peterson, Wendy Noort, Alberto Bertozzi, Gilbert Weidinger, George Posthuma, Dominic Grün, Willem J van der Laarse, Judith Klumperman, Richard T Jaspers, Kenneth D Poss, Alexander van Oudenaarden, Eldad Tzahor, Jeroen Bakkers
Publikováno v:
eLife, Vol 8 (2019)
While the heart regenerates poorly in mammals, efficient heart regeneration occurs in zebrafish. Studies in zebrafish have resulted in a model in which preexisting cardiomyocytes dedifferentiate and reinitiate proliferation to replace the lost myocar
Externí odkaz:
https://doaj.org/article/88c04f2d61d943049ee30a6c5dc0b5c0