Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Gilbert, Bensimon"'
Autor:
Tiong Y. Lim, Elena Perpiñán, Maria-Carlota Londoño, Rosa Miquel, Paula Ruiz, Ada S. Kurt, Elisavet Kodela, Amy R. Cross, Claudia Berlin, Joanna Hester, Fadi Issa, Abdel Douiri, Felix H. Volmer, Richard Taubert, Evangelia Williams, Anthony J. Demetris, Andrew Lesniak, Gilbert Bensimon, Juan José Lozano, Marc Martinez-Llordella, Tim Tree, Alberto Sánchez-Fueyo
Publikováno v:
Journal of Hepatology. 78:153-164
Background & Aims:CD4+CD25+Foxp3+regulatory T cells (Tregs) are essential to maintain immunological tolerance and have been shown to promote liver allograft tolerance in both rodents and humans. Low-dose IL-2 (LDIL-2) can expand human endogenous circ
Autor:
Jason A. Chen, Zhongbo Chen, Hyejung Won, Alden Y. Huang, Jennifer K. Lowe, Kevin Wojta, Jennifer S. Yokoyama, Gilbert Bensimon, P. Nigel Leigh, Christine Payan, Aleksey Shatunov, Ashley R. Jones, Cathryn M. Lewis, Panagiotis Deloukas, Philippe Amouyel, Christophe Tzourio, Jean-Francois Dartigues, Albert Ludolph, Adam L. Boxer, Jeff M. Bronstein, Ammar Al-Chalabi, Daniel H. Geschwind, Giovanni Coppola
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-11 (2018)
Abstract Background Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease for which the genetic contribution is incompletely understood. Methods We conducted a joint analysis of 5,523,934 imputed SNPs in two newly-genotyped progres
Externí odkaz:
https://doaj.org/article/38fd283c780d47908af18442210dfcca
Autor:
Tiong Yeng Lim, Elena Perpinan, Maria Carlota Londoño, Rosa Miquel, Paula Ruiz, Ada Kurt, Elisavet Codela, Amy Cross, Claudia Berlin, Joanna Hester, Fadi Issa, Abdel Douiri, Felix Volmer, Richard Taubert, Evangelia Williams, Jake Demetris, Andrew Lesniak, Gilbert Bensimon, Juanjo Lozano, Marc Martinez-Llordella, Timothy Tree, Alberto Sanchez-Fueyo
Publikováno v:
Journal of Hepatology. 77:S809
Autor:
Paul R. Heath, Cecilia Garlanda, Andrea Malaspina, P. Nigel Leigh, William Camu, Henrik Zetterberg, Christophe Masseguin, Gilbert Bensimon, Ilaria Giovannelli, Jean-Luc Veyrune, Abigail Brown, Ulf Andreasson, Dennis Wang, Nadhim Bayatti, Pamela J. Shaw, Massimo Locati, Ammar Al-Chalabi, Christine Payan, Safa Saker, Janine Kirby, Nicolas Pageot, John De Vos, Carey M. Suehs, Marius Mickunas, Raul Juntas-Morales, Timothy Tree
Publikováno v:
Brain Communications
Brain Communications, Oxford University Press on behalf of the Guarantors of Brain, 2021, 3 (3), ⟨10.1093/braincomms/fcab141⟩
Brain Communications, Oxford University Press on behalf of the Guarantors of Brain, 2021, 3 (3), ⟨10.1093/braincomms/fcab141⟩
Amyotrophic lateral sclerosis is a fatal neurodegenerative disease causing upper and lower motor neuron loss and currently no effective disease-modifying treatment is available. A pathological feature of this disease is neuroinflammation, a mechanism
Autor:
Schijven, D., Stevelink, R., Mccormack, M., van Rheenen, W., Luykx, J. J., Koeleman, B. P. C., Veldink, J. H., Aleksey, Shatunov, Mclaughlin, Russell L., van der Spek, Rick A. A., Alfredo, Iacoangeli, Kenna, Kevin P., van Eijk, Kristel R., Nicola, Ticozzi, Boris, Rogelj, Katarina, Vrabec, Metka, Ravnik-Glavač, Blaž, Koritnik, Janez, Zidar, Lea, Leonardis, Leja Dolenc Grošelj, Stéphanie, Millecamps, François, Salachas, Vincent, Meininger, Mamede de Carvalho, Susana, Pinto, Marta, Gromicho, Ana, Pronto-Laborinho, Mora, Jesus S., Ricardo, Rojas-García, Meraida, Polak, Siddharthan, Chandran, Shuna, Colville, Robert, Swingler, Morrison, Karen E., Shaw, Pamela J., John, Hardy, Orrell, Richard W., Alan, Pittman, Katie, Sidle, Pietro, Fratta, Andrea, Malaspina, Simon, Topp, Susanne, Petri, Susanna, Abdulla, Carsten, Drepper, Michael, Sendtner, Thomas, Meyer, Ophoff, Roel A., Staats, Kim A., Martina, Wiedau-Pazos, Catherine, Lomen-Hoerth, Van Deerlin, Vivianna M., Trojanowski, John Q., Lauren, Elman, Leo, Mccluskey, Nazli Basak, A., Thomas, Meitinger, Peter, Lichtner, Milena, Blagojevic-Radivojkov, Andres, Christian R., Gilbert, Bensimon, Bernhard, Landwehrmeyer, Alexis, Brice, Payan, Christine A. M., Safaa, Saker-Delye, Alexandra, Dürr, Wood, Nicholas W., Lukas, Tittmann, Wolfgang, Lieb, Andre, Franke, Marcella, Rietschel, Sven, Cichon, Nöthen, Markus M., Philippe, Amouyel, Christophe, Tzourio, Jean-François, Dartigues, Uitterlinden, Andre G., Fernando, Rivadeneira, Karol, Estrada, Albert, Hofman, Charles, Curtis, van der Kooi, Anneke J., Markus, Weber, Shaw, Christopher E., Smith, Bradley N., Daisy, Sproviero, Cristina, Cereda, Mauro, Ceroni, Luca, Diamanti, Roberto Del Bo, Stefania, Corti, Comi, Giacomo P., Sandra, D'Alfonso, Lucia, Corrado, Bertolin, Cinzia, Soraru', Gianni, Letizia, Mazzini, Viviana, Pensato, Cinzia, Gellera, Cinzia, Tiloca, Antonia, Ratti, Andrea, Calvo, Cristina, Moglia, Maura, Brunetti, Simona, Arcuti, Rosa, Capozzo, Chiara, Zecca, Christian, Lunetta, Silvana, Penco, Nilo, Riva, Alessandro, Padovani, Massimiliano, Filosto, Ian, Blair, Nicholson, Garth A., Rowe, Dominic B., Roger, Pamphlett, Kiernan, Matthew C., Julian, Grosskreutz, Witte, Otto W., Robert, Steinbach, Tino, Prell, Beatrice, Stubendorff, Ingo, Kurth, Hübner, Christian A., Nigel Leigh, P., Federico, Casale, Adriano, Chio, Ettore, Beghi, Elisabetta, Pupillo, Rosanna, Tortelli, Giancarlo, Logroscino, John, Powell, Ludolph, Albert C., Weishaupt, Jochen H., Wim, Robberecht, Philip Van Damme, Brown, Robert H., Glass, Jonathan D., Landers, John E., Orla, Hardiman, Andersen, Peter M., Philippe, Corcia, Patrick, Vourc'H, Vincenzo, Silani, van Es, Michael A., Jeroen Pasterkamp, R., Lewis, Cathryn M., Gerome, Breen, Ammar, Al-Chalabi, van den Berg, Leonard H., Veldink, Jan H., Daniela, Calini, Isabella, Fogh, Barbara, Castellotti, Franco, Taroni, Stella, Gagliardi, Giacomo, Comi, Sandra, D’Alfonso, Pegoraro, Elena, Giorgia, Querin, Francesca, Gerardi, Fabrizio, Rinaldi, Maria Sofia Cotelli, Luca, Chiveri, Maria Cristina Guaita, Patrizia, Perrone, Giancarlo, Comi, Carlo, Ferrarese, Lucio, Tremolizzo, Marialuisa, Delodovici, Giorgio, Bono, Stefania, Cammarosano, Antonio, Canosa, Dario, Cocito, Leonardo, Lopiano, Luca, Durelli, Bruno, Ferrero, Antonio, Bertolotto, Alessandro, Mauro, Luca, Pradotto, Roberto, Cantello, Enrica, Bersano, Dario, Giobbe, Maurizio, Gionco, Daniela, Leotta, Lucia, Appendino, Cavallo, Cavallo, Enrico, Odddenino, Claudio, Geda, Fabio, Poglio, Paola, Santimaria, Umberto, Massazza, Antonio, Villani, Roberto, Conti, Fabrizio, Pisano, Mario, Palermo, Franco, Vergnano, Paolo, Provera, Maria Teresa Penza, Marco, Aguggia, Nicoletta Di Vito, Piero, Meineri, Ilaria, Pastore, Paolo, Ghiglione, Danilo, Seliak, Nicola, Launaro, Giovanni, Astegiano, Bottacchi, Edo, Isabella Laura Simone, Stefano, Zoccolella, Michele, Zarrelli, Franco, Apollo, William, Camu, Jean Sebastien Hulot, Francois, Viallet, Philippe, Couratier, David, Maltete, Christine, Tranchant, Marie, Vidailhet, Bassel, Abou-Khalil, Pauls, Auce, Andreja, Avbersek, Melanie, Bahlo, David, J Balding, Thomas, Bast, Larry, Baum, Albert, J Becker, Felicitas, Becker, Bianca, Berghuis, Samuel, F Berkovic, Katja, E Boysen, Jonathan, P Bradfield, Lawrence, C Brody, Russell, J Buono, Ellen, Campbell, Gregory, D Cascino, Claudia, B Catarino, Gianpiero, L Cavalleri, Stacey, S Cherny, Krishna, Chinthapalli, Alison, J Coffey, Alastair, Compston, Antonietta, Coppola, Patrick, Cossette, John, J Craig, Gerrit-Jan de Haan, Peter De Jonghe, Carolien G, F de Kovel, Norman, Delanty, Chantal, Depondt, Orrin, Devinsky, Dennis, J Dlugos, Colin, P Doherty, Christian, E Elger, Johan, G Eriksson, Thomas, N Ferraro, Martha, Feucht, Ben, Francis, Jacqueline, A French, Saskia, Freytag, Verena, Gaus, Eric, B Geller, Christian, Gieger, Tracy, Glauser, Simon, Glynn, David, B Goldstein, Hongsheng, Gui, Youling, Guo, Kevin, F Haas, Hakon, Hakonarson, Kerstin, Hallmann, Sheryl, Haut, Erin, L Heinzen, Ingo, Helbig, Christian, Hengsbach, Helle, Hjalgrim, Michele, Iacomino, Andrés, Ingason, Michael, R Johnson, Reetta, Kälviäinen, Anne-Mari, Kantanen, Dalia, Kasperavičiūte, Dorothee Kasteleijn-Nolst Trenite, Heidi, E Kirsch, Robert, C Knowlton, Bobby P, C Koeleman, Roland, Krause, Martin, Krenn, Wolfram, S Kunz, Ruben, Kuzniecky, Patrick, Kwan, Dennis, Lal, Yu-Lung, Lau, Anna-Elina, Lehesjoki, Holger, Lerche, Costin, Leu, Dick, Lindhout, Warren, D Lo, Iscia, Lopes-Cendes, Daniel, H Lowenstein, Alberto, Malovini, Anthony, G Marson, Thomas, Mayer, Mark, Mccormack, James, L Mills, Nasir, Mirza, Martina, Moerzinger, Rikke, S Møller, Anne, M Molloy, Hiltrud, Muhle, Mark, Newton, Ping-Wing, Ng, Markus, M Nöthen, Peter, Nürnberg, Terence, J O’Brien, Karen, L Oliver, Aarno, Palotie, Faith, Pangilinan, Sarah, Peter, Slavé, Petrovski, Annapurna, Poduri, Michael, Privitera, Rodney, Radtke, Sarah, Rau, Philipp, S Reif, Eva, M Reinthaler, Felix, Rosenow, Josemir, W Sander, Thomas, Sander, Theresa, Scattergood, Steven, C Schachter, Christoph, J Schankin, Ingrid, E Scheffer, Bettina, Schmitz, Susanne, Schoch, Pak, C Sham, Jerry, J Shih, Graeme, J Sills, Sanjay, M Sisodiya, Lisa, Slattery, Alexander, Smith, David, F Smith, Michael, C Smith, Philip, E Smith, Anja C, M Sonsma, Doug, Speed, Michael, R Sperling, Bernhard, J Steinhoff, Ulrich, Stephani, Remi, Stevelink, Konstantin, Strauch, Pasquale, Striano, Hans, Stroink, Rainer, Surges, K Meng Tan, Liu Lin Thio, G Neil Thomas, Marian, Todaro, Rossana, Tozzi, Maria, S Vari, Eileen P, G Vining, Frank, Visscher, Sarah von Spiczak, Nicole, M Walley, Yvonne, G Weber, Zhi, Wei, Judith, Weisenberg, Christopher, D Whelan, Peter, Widdess-Walsh, Markus, Wolff, Stefan, Wolking, Wanling, Yang, Federico, Zara, Fritz, Zimprich
Publikováno v:
Project MinE ALS GWAS Consortium & Morrison, K 2020, ' Analysis of shared common genetic risk between amyotrophic lateral sclerosis and epilepsy ', Neurobiology of Aging, vol. 92, pp. 153.e1-153.e5 . https://doi.org/10.1016/j.neurobiolaging.2020.04.011
Neurobiology of Aging
Neurobiology of aging
Neurobiology of Aging
Neurobiology of aging
Because hyper-excitability has been shown to be a shared pathophysiological mechanism, we used the latest and largest genome-wide studies in amyotrophic lateral sclerosis (n = 36,052) and epilepsy (n = 38,349) to determine genetic overlap between the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30266778acc091f0f35d4e5c44b9d50e
https://lirias.kuleuven.be/handle/123456789/681935
https://lirias.kuleuven.be/handle/123456789/681935
Autor:
Raul Juntas-Morales, Marius Mickunas, Massimo Locati, Timothy Tree, Nicolas Pageot, John De Vos, Jean-Luc Veyrune, P. Nigel Leigh, William Camu, Ulf Andreasson, Christine Payan, Janine Kirby, Pamela J. Shaw, Ammar Al-Chalabi, Christophe Masseguin, Safa Saker, Carey M. Suehs, Cecilia Garlanda, Henrik Zetterberg, Andrea Malaspina, Gilbert Bensimon
Publikováno v:
EBioMedicine
EBioMedicine, Elsevier, 2020, 59, pp.102844. ⟨10.1016/j.ebiom.2020.102844⟩
EBioMedicine, 2020, 59, pp.102844. ⟨10.1016/j.ebiom.2020.102844⟩
EBioMedicine, Elsevier, 2020, 59, pp.102844. ⟨10.1016/j.ebiom.2020.102844⟩
EBioMedicine, 2020, 59, pp.102844. ⟨10.1016/j.ebiom.2020.102844⟩
Background\ud \ud Low-dose interleukin-2 (ld-IL-2) enhances regulatory T-cell (Treg) function in auto-inflammatory conditions. Neuroinflammation being a pathogenic feature of amyotrophic lateral sclerosis (ALS), we evaluated the pharmacodynamics and
Autor:
Yann Nadjar, Paul Gordon, Philippe Corcia, Gilbert Bensimon, Laurence Pieroni, Vincent Meininger, François Salachas
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45034 (2012)
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder caused by the loss of motor neurons. Its etiology remains unknown, but several hypothesis have been raised to explain motor neuron death, including oxidative stress. Dysr
Externí odkaz:
https://doaj.org/article/75325a1ac1df4aab8e6d4062d9ced9a5
Autor:
Ashley R. Jones, Christophe Tzourio, Jason A. Chen, Christine Payan, Aleksey Shatunov, Gilbert Bensimon, Panagiotis Deloukas, Cathryn M. Lewis, Kevin Wojta, Hyejung Won, Ammar Al-Chalabi, Philippe Amouyel, Albert C. Ludolph, Jean-François Dartigues, Adam L. Boxer, Jeff M. Bronstein, P. Nigel Leigh, Daniel H. Geschwind, Jennifer S. Yokoyama, Jennifer K. Lowe, Giovanni Coppola, Alden Y. Huang, Zhongbo Chen
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-11 (2018)
Molecular Neurodegeneration
Molecular Neurodegeneration, 2018, 13 (1), pp.41. ⟨10.1186/s13024-018-0270-8⟩
Molecular Neurodegeneration, BioMed Central, 2018, 13 (1), pp.41. ⟨10.1186/s13024-018-0270-8⟩
Molecular neurodegeneration, vol 13, iss 1
Chen, J A, Chen, Z, Won, H, Huang, A Y, Lowe, J K, Wojta, K, Yokoyama, J S, Bensimon, G, Leigh, P N, Payan, C, Shatunov, A, Jones, A R, Lewis, C M, Deloukas, P, Amouyel, P, Tzourio, C, Dartigues, J F, Ludolph, A, Boxer, A L, Bronstein, J M, Al-Chalabi, A, Geschwind, D H & Coppola, G 2018, ' Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases ', Molecular Neurodegeneration, vol. 13, no. 1, 41 . https://doi.org/10.1186/s13024-018-0270-8
Molecular Neurodegeneration
Molecular Neurodegeneration, 2018, 13 (1), pp.41. ⟨10.1186/s13024-018-0270-8⟩
Molecular Neurodegeneration, BioMed Central, 2018, 13 (1), pp.41. ⟨10.1186/s13024-018-0270-8⟩
Molecular neurodegeneration, vol 13, iss 1
Chen, J A, Chen, Z, Won, H, Huang, A Y, Lowe, J K, Wojta, K, Yokoyama, J S, Bensimon, G, Leigh, P N, Payan, C, Shatunov, A, Jones, A R, Lewis, C M, Deloukas, P, Amouyel, P, Tzourio, C, Dartigues, J F, Ludolph, A, Boxer, A L, Bronstein, J M, Al-Chalabi, A, Geschwind, D H & Coppola, G 2018, ' Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases ', Molecular Neurodegeneration, vol. 13, no. 1, 41 . https://doi.org/10.1186/s13024-018-0270-8
Background Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease for which the genetic contribution is incompletely understood. Methods We conducted a joint analysis of 5,523,934 imputed SNPs in two newly-genotyped progressive supr
Autor:
Christine A M Payan, François Viallet, Bernhard G Landwehrmeyer, Anne-Marie Bonnet, Michel Borg, Franck Durif, Lucette Lacomblez, Frédéric Bloch, Marc Verny, Jacques Fermanian, Yves Agid, Albert C Ludolph, Peter N Leigh, Gilbert Bensimon, NNIPPS Study Group
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22293 (2011)
The Natural History and Neuroprotection in Parkinson Plus Syndromes (NNIPPS) study was a large phase III randomized placebo-controlled trial of riluzole in Progressive Supranuclear Palsy (PSP, n = 362) and Multiple System Atrophy (MSA, n = 398). To a
Externí odkaz:
https://doaj.org/article/a2e443fa8eef46ee84896ee858169e23
Autor:
Paul McCrone, Christine Anne Mary Payan, Martin Knapp, Albert Ludolph, Yves Agid, P Nigel Leigh, Gilbert Bensimon, NNIPPS Study Group
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24369 (2011)
Progressive supranuclear palsy (PSP) and multiple system atrophy (MSA) are progressive disabling neurological conditions usually fatal within 10 years of onset. Little is known about the economic costs of these conditions. This paper reports service
Externí odkaz:
https://doaj.org/article/08647b2ae1de4b26b8b33f163ec58e67