Zobrazeno 1 - 10
of 349
pro vyhledávání: '"Gilbert, Arthur"'
Autor:
Liam Berry, Quinn Neale, Rajat Arora, Danyel Ramirez, Marc Brizuela, Ronald Domalaon, Gilbert Arthur, Frank Schweizer
Publikováno v:
Antibiotics, Vol 13, Iss 1, p 43 (2024)
Colistin is primarily used as a last resort antibiotic against highly resistant Gram-negative bacteria (GNB). Rising rates of colistin resistance, however, may limit future use of this agent. The anthelmintic drug niclosamide has been shown to enhanc
Externí odkaz:
https://doaj.org/article/e42dabfef8674835835c44924874d5e6
Autor:
Karan Gandhi, Shiv Dhiman, Rajat Arora, Danzel Marie Ramirez, Danyel Ramirez, Gilbert Arthur, Frank Schweizer
Publikováno v:
Antibiotics, Vol 12, Iss 8, p 1261 (2023)
Metal ions, including Fe3+, affect the target site binding of some antibiotics and control the porin- and siderophore-mediated uptake of antibiotics. Amphiphilic tobramycins are an emerging class of antibiotic potentiators capable of synergizing with
Externí odkaz:
https://doaj.org/article/84ba7ad4046c446ea8415af73399ae5c
Autor:
Danyel Ramirez, Liam Berry, Ronald Domalaon, Yanqi Li, Gilbert Arthur, Ayush Kumar, Frank Schweizer
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Recently reported peptidomimetics with increased resistance to trypsin were shown to sensitize priority multidrug-resistant (MDR) Gram-negative bacteria to novobiocin and rifampicin. To further optimize proteolytic stability, β-amino acid-containing
Externí odkaz:
https://doaj.org/article/83e6e1cd95114ea296ce1175ada1d723
Autor:
Mark W Nachtigal, Paris Musaphir, Shiv Dhiman, Alon D Altman, Frank Schweizer, Gilbert Arthur
Publikováno v:
Translational Oncology, Vol 14, Iss 11, Pp 101203- (2021)
Chemotherapy resistant high grade serous ovarian cancer remains a clinically intractable disease with a high rate of mortality. We tested a novel glycosylated antitumor ether lipid called l-Rham to assess the in vitro and in vivo efficacy on high gra
Externí odkaz:
https://doaj.org/article/f1a65bf9ad1c43518cf44ad5fcf60d9f
Publikováno v:
Antibiotics, Vol 11, Iss 10, p 1277 (2022)
Polymyxins are considered a last-line treatment against infections caused by multidrug-resistant (MDR) Gram-negative bacteria. In addition to their use as a potent antibiotic, polymyxins have also been utilized as outer membrane (OM) permeabilizers,
Externí odkaz:
https://doaj.org/article/39e23cd261fe44efbeac028fca25e60e
Publikováno v:
ACS Infectious Diseases. 9:864-885
Autor:
Ayodeji O. Oriola, Adetunji J. Aladesanmi, Thomas O. Idowu, Ezekiel O. Akinkunmi, Adebola O. Oyedeji, Makanjuola O. Ogunsina, Gilbert Arthur, Frank Schweizer
Publikováno v:
Chemistry Africa. 5:1959-1966
Autor:
Amani I. Moraya, Jennifer L. Ali, Pranati Samadder, Lisa Liang, Ludivine Coudière Morrison, Tamra E. Werbowetski-Ogilvie, Makanjuola Ogunsina, Frank Schweizer, Gilbert Arthur, Mark W. Nachtigal
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-13 (2017)
Abstract Background Chemotherapy resistance is one of the major factors contributing to mortality from human epithelial ovarian cancer (EOC). Identifying drugs that can effectively kill chemotherapy-resistant EOC cells would be a major advance in red
Externí odkaz:
https://doaj.org/article/4d674fe80e4341f18add9d702a408c48
Autor:
Makanjuola Ogunsina, Pranati Samadder, Temilolu Idowu, Mark Nachtigal, Frank Schweizer, Gilbert Arthur
Publikováno v:
Molecules, Vol 25, Iss 3, p 566 (2020)
A major impediment to successful cancer treatment is the inability of clinically available drugs to kill drug-resistant cancer cells. We recently identified metabolically stable l-glucosamine-based glycosylated antitumor ether lipids (GAELs) that wer
Externí odkaz:
https://doaj.org/article/d19affeed2994b37906d0652e9810e13