Impact of mobile and stationary phases on siRNA duplex stability in liquid chromatography.

Autor: Gilar M; Waters Corporation, 34 Maple Street, Milford, MA, 01757, USA. Electronic address: martin_gilar@waters.com., Redstone S; Waters Corporation, 34 Maple Street, Milford, MA, 01757, USA., Gomes A; Waters Corporation, 34 Maple Street, Milford, MA, 01757, USA.

Publikováno v: Journal of chromatography. A [J Chromatogr A] 2024 Sep 27; Vol. 1733, pp. 465285. Date of Electronic Publication: 2024 Aug 17.

Hydrophilic interaction liquid chromatography with mass spectrometry for the separation and identification of antisense oligonucleotides impurities and nusinersen metabolites.

Autor: Vosáhlová Z; Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, Hlavova 8, 12800, Prague, Czech Republic., Kalíková K; Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, Hlavova 8, 12800, Prague, Czech Republic. Electronic address: kveta.kalikova@natur.cuni.cz., Gilar M; Waters Corporation, 34 Maple Street, Milford, MA 01757, USA., Szymarek J; Department of Developmental Neurology, Medical University of Gdansk, 7 Dębinki Str., PL-80-952, Gdańsk, Poland., Mazurkiewicz-Bełdzińska M; Department of Developmental Neurology, Medical University of Gdansk, 7 Dębinki Str., PL-80-952, Gdańsk, Poland., Studzińska S; Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, Hlavova 8, 12800, Prague, Czech Republic; Chair of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, 7 Gagarin Str., PL-87-100 Toruń, Poland; Centre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Toruń, 4 Wilenska St., 87-100 Toruń, Poland. Electronic address: kowalska@umk.pl.

Publikováno v: Journal of chromatography. A [J Chromatogr A] 2024 Jan 04; Vol. 1713, pp. 464535. Date of Electronic Publication: 2023 Nov 26.

Liquid Chromatography Methods for Analysis of mRNA Poly(A) Tail Length and Heterogeneity.

Autor: Gilar M; Separations R&D, Waters Corporation, Milford, Massachusetts 01757, United States., Doneanu C; Discovery and Development, Waters Corporation, Milford, Massachusetts 01757, United States., Gaye MM; Consumables Research, Waters Corporation, Milford, Massachusetts 01757, United States.

Publikováno v: Analytical chemistry [Anal Chem] 2023 Sep 26; Vol. 95 (38), pp. 14308-14316. Date of Electronic Publication: 2023 Sep 11.

Phosphorothioate oligonucleotides separation in ion-pairing reversed-phase liquid chromatography: effect of temperature.

Autor: Kadlecová Z; Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, Hlavova 8, 12800, Prague, Czech Republic., Kalíková K; Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, Hlavova 8, 12800, Prague, Czech Republic. Electronic address: kalikova@natur.cuni.cz., Tesařová E; Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, Hlavova 8, 12800, Prague, Czech Republic., Gilar M; Waters Corporation, 34 Maple Street, Milford, MA 01757, United States of America. Electronic address: Martin_Gilar@waters.com.

Publikováno v: Journal of chromatography. A [J Chromatogr A] 2022 Oct 11; Vol. 1681, pp. 463473. Date of Electronic Publication: 2022 Sep 07.

Phosphorothioate oligonucleotides separation in ion-pairing reversed-phase liquid chromatography: Effect of ion-pairing system.

Autor: Kadlecová Z; Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, Hlavova 8, 12800, Prague, Czech Republic., Kalíková K; Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, Hlavova 8, 12800, Prague, Czech Republic. Electronic address: kalikova@natur.cuni.cz., Tesařová E; Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, Hlavova 8, 12800, Prague, Czech Republic., Gilar M; Waters Corporation, 34 Maple Street, Milford, MA 01757, United States. Electronic address: Martin_Gilar@waters.com.

Publikováno v: Journal of chromatography. A [J Chromatogr A] 2022 Aug 02; Vol. 1676, pp. 463201. Date of Electronic Publication: 2022 Jun 07.