Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Gilad Landan"'
Autor:
Ran Brosh, Reut Shalgi, Atar Liran, Gilad Landan, Katya Korotayev, Giang Huong Nguyen, Espen Enerly, Hilde Johnsen, Yosef Buganim, Hilla Solomon, Ido Goldstein, Shalom Madar, Naomi Goldfinger, Anne‐Lise Børresen‐Dale, Doron Ginsberg, Curtis C Harris, Yitzhak Pilpel, Moshe Oren, Varda Rotter
Publikováno v:
Molecular Systems Biology, Vol 4, Iss 1, Pp 1-15 (2008)
Abstract Normal cell growth is governed by a complicated biological system, featuring multiple levels of control, often deregulated in cancers. The role of microRNAs (miRNAs) in the control of gene expression is now increasingly appreciated, yet thei
Externí odkaz:
https://doaj.org/article/b98aad89b9fd4b26ad4026c72d97c423
Autor:
Li Jia, Gilad Landan, Mark Pomerantz, Rami Jaschek, Paula Herman, David Reich, Chunli Yan, Omar Khalid, Phil Kantoff, William Oh, J Robert Manak, Benjamin P Berman, Brian E Henderson, Baruch Frenkel, Christopher A Haiman, Matthew Freedman, Amos Tanay, Gerhard A Coetzee
Publikováno v:
PLoS Genetics, Vol 5, Iss 8, p e1000597 (2009)
Multiple discrete regions at 8q24 were recently shown to contain alleles that predispose to many cancers including prostate, breast, and colon. These regions are far from any annotated gene and their biological activities have been unknown. Here we p
Externí odkaz:
https://doaj.org/article/3036cf999c164d04866aeb3abc4f882d
Autor:
Nir Friedman, Yael Fried, Amos Tanay, Zohar Shipony, Gilad Landan, Shlomit Reich Zeliger, Netta Mendelson Cohen, Elad Chomsky, Zohar Mukamel, Elena Ainbinder
Publikováno v:
Nature. 513:115-119
Stable maintenance of gene regulatory programs is essential for normal function in multicellular organisms. Epigenetic mechanisms, and DNA methylation in particular, are hypothesized to facilitate such maintenance by creating cellular memory that can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7a59a7ae2c152b372979a7f0ca37d3
https://doi.org/10.1038/nature13458
https://doi.org/10.1038/nature13458
Autor:
Ran Brosh, Alina Molchadsky, Naomi Goldfinger, Netta Mendelson Cohen, Daniela Amann Zalcenstein, Gilad Landan, Amir Bar, Amos Tanay, Einav Nili Gal-Yam, Shirley Horn-Saban, Varda Rotter, Adi Zundelevich, Zohar Mukamel
Publikováno v:
Nature Genetics. 44:1207-1214
DNA methylation has been comprehensively profiled in normal and cancer cells, but the dynamics that form, maintain and reprogram differentially methylated regions remain enigmatic. Here, we show that methylation patterns within populations of cells f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d34a91ebf864cbcbd101b18dc255edd
https://doi.org/10.1038/ng.2442
https://doi.org/10.1038/ng.2442
Autor:
Amos Tanay, Marjon J.A.M. Verstegen, Yuva Oz, Elzo de Wit, Britta A M Bouwman, Gilad Landan, Christian Valdes-Quezada, Michael Hoichman, Sjoerd J B Holwerda, Harmen J.G. van de Werken, Ran Chachik, Wouter de Laat, Erik Splinter, Petra Klous
Publikováno v:
Nature Methods, 9(10), 969-972. Nature Publishing Group
Nature Methods
Nature Methods
Regulatory DNA elements can control the expression of distant genes via physical interactions. Here we present a cost-effective methodology and computational analysis pipeline for robust characterization of the physical organization around selected p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54aad271a9f3b1477d2e4af0ce6a934d
https://doi.org/10.1038/nmeth.2173
https://doi.org/10.1038/nmeth.2173
Autor:
Pedro Olivares-Chauvet, Shai Izraeli, Omer Schwartzman, Amos Tanay, Gilad Landan, Zohar Mukamel, Noa Oded-Elkayam, Yaniv Lubling
Publikováno v:
Nature methods. 13(8)
We developed a targeted chromosome conformation capture (4C) approach that uses unique molecular identifiers (UMIs) to derive high-complexity quantitative chromosome contact profiles with controlled signal-to-noise ratios. UMI-4C detects chromosomal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02bb47af0e80894878026e1f13ff42af
https://pubmed.ncbi.nlm.nih.gov/27376768
https://pubmed.ncbi.nlm.nih.gov/27376768
Autor:
Yoav Shetzer, S. Levin, Marc Zapatka, Noa Rivlin, Dana Pe'er, Varda Rotter, Ira Kogan-Sakin, Gilad Landan, N. Dinowitz, Rachel Sarig, Peter Lichter, Ido Goldstein, Naomi Goldfinger, Gabriela Koifman, Tom Kaufman, S. Kagan, Bernhard Radlwimmer, Alina Molchadsky, Ronit Aloni-Grinstein, Meital Charni
Publikováno v:
Cell death and differentiation. 21(9)
p53 loss of heterozygosity (p53LOH) is frequently observed in Li-Fraumeni syndrome (LFS) patients who carry a mutant (Mut) p53 germ-line mutation. Here, we focused on elucidating the link between p53LOH and tumor development in stem cells (SCs). Alth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5a373d3ada072e08079bfc95994e5d
https://pubmed.ncbi.nlm.nih.gov/24832469
https://pubmed.ncbi.nlm.nih.gov/24832469
Autor:
Gilad Landan, Netta Mendelson Cohen, Shoukhrat Mitalipov, Vikas Dighe, Arnar Palsson, Sigrún Reynisdóttir, Amos Tanay
Publikováno v:
Genome research. 19(12)
DNA methylation is an important epigenetic mechanism, affecting normal development and playing a key role in reprogramming epigenomes during stem cell derivation. Here we report on DNA methylation patterns in native monkey embryonic stem cells (ESCs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd573a3a377b3ef8b6b248662fe24708
https://pubmed.ncbi.nlm.nih.gov/19887575
https://pubmed.ncbi.nlm.nih.gov/19887575
Autor:
Mark Pomerantz, J. Robert Manak, William Oh, Omar Khalid, Gilad Landan, Baruch Frenkel, Rami Jaschek, Christopher A. Haiman, Paula Herman, Amos Tanay, Benjamin P. Berman, Brian E. Henderson, David Reich, Li Jia, Phil Kantoff, Matthew L. Freedman, Chunli Yan, Gerhard A. Coetzee
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 5, Iss 8, p e1000597 (2009)
PLoS Genetics, Vol 5, Iss 8, p e1000597 (2009)
Multiple discrete regions at 8q24 were recently shown to contain alleles that predispose to many cancers including prostate, breast, and colon. These regions are far from any annotated gene and their biological activities have been unknown. Here we p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d64f231d933654ffe743183844dccc
https://pubmed.ncbi.nlm.nih.gov/19680443
https://pubmed.ncbi.nlm.nih.gov/19680443
Autor:
Gilad Landan, Jeanette Baker, Eugene C. Butcher, Ryosei Nishimura, Christopher H. Contag, Georg F. Beilhack, Enosh M. Baker, Andreas Beilhack, Edward I. Herman, Stephan Schulz, Robert S. Negrin
Publikováno v:
Blood. 111(5)
In acute graft-versus-host disease (aGVHD), donor T cells attack the recipient's gastrointestinal tract, liver, and skin. We hypothesized that blocking access to distinct lymphoid priming sites may alter the specific organ tropism and prevent aGVHD d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c28b3a6e4d433e4106b99ccaa7b096
https://pubmed.ncbi.nlm.nih.gov/17989315
https://pubmed.ncbi.nlm.nih.gov/17989315