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Akademický článek

Prebiotic Treatment in Patients with Nonalcoholic Fatty Liver Disease (NAFLD)—A Randomized Pilot Trial

Autor: Naama Reshef, Uri Gophna, Leah Reshef, Fred Konikoff, Gila Gabay, Taiba Zornitzki, Hilla Knobler, Yaakov Maor

Publikováno v: Nutrients, Vol 16, Iss 11, p 1571 (2024)

Several studies show that gut microbiotas in patients with nonalcoholic fatty liver disease (NAFLD) differ from those in a healthy population, suggesting that this alteration plays a role in NAFLD pathogenesis. We investigated whether prebiotic admin

Externí odkaz: https://doaj.org/article/c8cdfce3856046c3967169d0aa4b24e9

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Interactions between the intestinal microbiota and bile acids in gallstones patients

Autor: Uri Gophna, Fred M. Konikoff, Timna Naftali, Gila Gabay, Yossi Paitan, Leah Reshef, Nirit Keren

Publikováno v: Environmental Microbiology Reports. 7:874-880

Cholecystectomy, surgical removal of the gallbladder, changes bile flow to the intestine and can therefore alter the bidirectional interactions between bile acids (BAs) and the intestinal microbiota. We quantified and correlated BAs and bacterial com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41dcbdeba2281b9292c1917681bef79a
https://doi.org/10.1111/1758-2229.12319

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Low-Dose Cannabidiol Is Safe but Not Effective in the Treatment for Crohn's Disease, a Randomized Controlled Trial

Autor: Asaf Stein, Fabiana Benjaminov, Miriam Bronshtain, Fred M. Konikoff, Amir Marii, Ido Laish, Gila Gabay, Timna Naftali, Refael Mechulam

Publikováno v: Digestive diseases and sciences. 62(6)

Cannabidiol (CBD) is an anti-inflammatory cannabinoid shown to be beneficial in a mouse model of IBD. Lacking any central effect, cannabidiol is an attractive option for treating inflammatory diseases.To assess the effects of cannabidiol on Crohn's d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76974cdfa9084436edc732fa2d4c0eb
https://pubmed.ncbi.nlm.nih.gov/28349233

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Interactions between the intestinal microbiota and bile acids in gallstones patients

Autor: Nirit, Keren, Fred M, Konikoff, Yossi, Paitan, Gila, Gabay, Leah, Reshef, Timna, Naftali, Uri, Gophna

Publikováno v: Environmental microbiology reports. 7(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a3f6395811ba1919b20cb0e7238b4c9b
https://pubmed.ncbi.nlm.nih.gov/26149537

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High levels of glucocorticoid receptors in patients with active Crohn's disease may predict steroid resistance

Autor: R Towers, Gila Gabay, B Novis, M Carlebach, A Klein, Timna Naftali

Publikováno v: Clinical and Experimental Immunology. 141:357-362

Summary Up to 20% of Crohn's disease (CD) patients respond poorly to glucocorticoids (GC). A product of an alternative splicing of the glucocorticoid receptor (GR) premRNA, GRβ, may play a role as a dominant inhibitor of the glucocorticoid response.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d8192c5b2e1530c5322664e7ee76cd
https://doi.org/10.1111/j.1365-2249.2005.02846.x

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Soluble Syndecan-1 Levels Are Elevated in Patients with Inflammatory Bowel Disease

Autor: Timna Naftali, Doron Yablecovitch, Maytal Shabat-Simon, Fred M. Konikoff, Ido Laish, Gila Gabay, Asaf Oren, Assaf Stein

Publikováno v: Digestive diseases and sciences. 60(8)

Syndecan-1 plays a central role in maintaining normal intestinal barrier function. Shedding of syndecan-1, reflected by soluble syndecan-1 serum concentrations, is highly regulated by inflammation.To determine soluble syndecan-1 levels in inflammator

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac63ad5c01f3ba139f4be36580cded4
https://pubmed.ncbi.nlm.nih.gov/25911586

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Interleukin-18 and its binding protein in patients with inflammatory bowel disease during remission and exacerbation

Autor: Timna, Naftali, Daniella, Novick, Gila, Gabay, Menahem, Rubinstein, Ben, Novis

Publikováno v: The Israel Medical Association journal : IMAJ. 9(7)

Crohn's disease and ulcerative colitis are inflammatory bowel diseases with an unknown etiology. Interleukin-18 is a pro-inflammatory cytokine that is up-regulated in Crohn's disease. IL-18 binding protein neutralizes IL-18. The relationship of IL-18

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::af2ed9e377783f61129304593e97daa9
https://pubmed.ncbi.nlm.nih.gov/17710779

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