Coupling killing to neutralization: combined therapy with ceftriaxone/Pep19-2.5 counteracts sepsis in rabbits.

Autor: Bárcena-Varela S; Department of Microbiology and Parasitology, Universidad de Navarra, Pamplona, Spain., Martínez-de-Tejada G; Department of Microbiology and Parasitology, Universidad de Navarra, Pamplona, Spain., Martin L; Department of Intensive Care and Intermediate Care, University Hospital Aachen, Aachen, Germany., Schuerholz T; Department of Anaesthesia and Intensive Care, University of Rostock, Rostock, Germany., Gil-Royo AG; Department of Pharmacology and Toxicology, Universidad de Navarra, Pamplona, Spain., Fukuoka S; National Institute of Advanced Industrial Science and Technology AIST, Takamatsu, Japan., Goldmann T; Department of Pathology, University Hospital of Luebeck, Luebeck, Germany.; Department of Pathology, Leibniz Research Center, Borstel, Germany.; Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Großhansdorf, Germany., Droemann D; Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Großhansdorf, Germany.; Medical Clinic III, Pulmonology/Infectious Diseases, University Hospital Schleswig-Holstein, Luebeck, Germany., Correa W; Division of Biophysics, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Borstel, Germany., Gutsmann T; Division of Biophysics, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Borstel, Germany., Brandenburg K; Division of Biophysics, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Borstel, Germany., Heinbockel L; Division of Biophysics, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Borstel, Germany.

Publikováno v: Experimental & molecular medicine [Exp Mol Med] 2017 Jun 16; Vol. 49 (6), pp. e345. Date of Electronic Publication: 2017 Jun 16.

Safety and liver transduction efficacy of rAAV5-cohPBGD in nonhuman primates: a potential therapy for acute intermittent porphyria.

Autor: Pañeda A; 1 Division of Hepatology and Gene Therapy, Center for Applied Medical Research , 31008 Pamplona, Spain ., Lopez-Franco E, Kaeppel C, Unzu C, Gil-Royo AG, D'Avola D, Beattie SG, Olagüe C, Ferrero R, Sampedro A, Mauleon I, Hermening S, Salmon F, Benito A, Gavira JJ, Cornet ME, del Mar Municio M, von Kalle C, Petry H, Prieto J, Schmidt M, Fontanellas A, González-Aseguinolaza G

Publikováno v: Human gene therapy [Hum Gene Ther] 2013 Dec; Vol. 24 (12), pp. 1007-17.