Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Gil-Ran Kim"'
Autor:
Min-Ji Cho, Hong-Gyun Lee, Jae-Won Yoon, Gil-Ran Kim, Ja-Hyun Koo, Reshma Taneja, Brian T. Edelson, You Jeong Lee, Je-Min Choi
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 5, Pp 1033-1045 (2023)
Abstract Memory-phenotype (MP) CD4+ T cells are a substantial population of conventional T cells that exist in steady-state mice, yet their immunological roles in autoimmune disease remain unclear. In this work, we unveil a unique phenotype of MP CD4
Externí odkaz:
https://doaj.org/article/6382e334850643cbaedf9b44db87539e
Autor:
Woo-Sung Lee, Kyung-Ho Nam, Jong Hoon Kim, Won-Ju Kim, Jeong Eun Kim, Eui-Cheol Shin, Gil-Ran Kim, Je-Min Choi
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Psoriasis is a chronic inflammatory skin disease characterized by hyperplasia of keratinocytes and immune cell infiltration. The IL-17-producing T cells play a key role in psoriasis pathogenesis, while regulatory T (Treg) cells are diminished during
Externí odkaz:
https://doaj.org/article/0eed9f6b34d9431cbe564d0267be7c0a
Autor:
Gil‐Ran Kim, Won‐Ju Kim, Sangho Lim, Hong‐Gyun Lee, Ja‐Hyun Koo, Kyung‐Ho Nam, Sung‐Min Kim, Sung‐Dong Park, Je‐Min Choi
Publikováno v:
Advanced Science, Vol 8, Iss 14, Pp n/a-n/a (2021)
Abstract Regulatory T cells play a key role in immune tolerance to self‐antigens, thereby preventing autoimmune diseases. However, no drugs targeting Treg cells have been approved for clinical trials yet. Here, a chimeric peptide is generated by co
Externí odkaz:
https://doaj.org/article/76ec2ec724f14bf68bf89bab503408c6
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1134 (2021)
T cells are key immune cells involved in the pathogenesis of several diseases, rendering them important therapeutic targets. Although drug delivery to T cells is the subject of continuous research, it remains challenging to deliver drugs to primary T
Externí odkaz:
https://doaj.org/article/5e8aa0a7a70a4f638f6259f2c162c271
Autor:
Gil-Ran Kim, Je-Min Choi
Publikováno v:
Molecules and Cells. 45:513-521
Cytotoxic T lymphocyte antigen-4 (CTLA-4) is an immune checkpoint molecule that is mainly expressed on activated T cells and regulatory T (Treg) cells that inhibits T-cell activation and regulates immune homeostasis. Due to the crucial functions of C
Publikováno v:
Trends in Molecular Medicine. 28:482-496
With the advent of cancer immunotherapy, immunomodulation has emerged as an important strategy for the treatment of various diseases. We review recent advances in clinical trials of cell-penetrating peptide (CPP) applications for immunotherapy and al
Autor:
Je-Min Choi, Min-Zi Cho, Hong-Gyun Lee, Jae-Won Yoon, Gil-Ran Kim, Ja-Hyun Koo, Reshma Taneja, Brian Edelson, You Jeong Lee
Memory-phenotype (MP) CD4+ T cells are a substantial population of conventional T cells that exist in steady-state mice, and their immunologic functions in autoimmune disease have not yet been studied. In this work, we unveil a unique phenotype of MP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d80b82ab34813e32fab232c317be707
https://doi.org/10.21203/rs.3.rs-2219047/v1
https://doi.org/10.21203/rs.3.rs-2219047/v1
Autor:
Min-Zi Cho, Hong-Gyun Lee, Jae-Won Yoon, Gil-Ran Kim, Ja-Hyun Koo, Reshma Taneja, Brian T. Edelson, You Jeong Lee, Je-Min Choi
Memory-phenotype (MP) CD4+T cells are a substantial population of conventional T cells that exist in steady-state mice, and their immunologic functions in autoimmune disease have not yet been studied. In this work, we unveil a unique phenotype of MP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::934ecedfbf5fe24395aee6fb8c034fee
https://doi.org/10.1101/2022.06.17.496529
https://doi.org/10.1101/2022.06.17.496529
Autor:
Myeong Joon Kim, Kyungsoo Kim, Hyo Jin Park, Gil-Ran Kim, Kyeong Hee Hong, Ji Hoon Oh, Jimin Son, Dong Jin Park, Dahae Kim, Je-Min Choi, Insuk Lee, Sang-Jun Ha
Publikováno v:
Nature immunology.
Regulatory T (T
Autor:
Je-Min Choi, Kyung Ho Nam, Ja Hyun Koo, Won Ju Kim, Hong Gyun Lee, Gil Ran Kim, Sangho Lim, Sung Min Kim, Sung Dong Park
Publikováno v:
Advanced Science
Advanced Science, Vol 8, Iss 14, Pp n/a-n/a (2021)
Advanced Science, Vol 8, Iss 14, Pp n/a-n/a (2021)
Regulatory T cells play a key role in immune tolerance to self‐antigens, thereby preventing autoimmune diseases. However, no drugs targeting Treg cells have been approved for clinical trials yet. Here, a chimeric peptide is generated by conjugation