Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Gil Shoham"'
Autor:
Shifra Lansky, Rachel Salama, Xevi Biarnés, Omer Shwartstein, Dina Schneidman-Duhovny, Antoni Planas, Yuval Shoham, Gil Shoham
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Lansky et al. describe the structural analysis of an ultra-multimodular GH43 arabinanase, AbnA. They discover a new carbohydrate binding module and analyze the large conformational transitions of the enzyme with the integrative structure determinatio
Externí odkaz:
https://doaj.org/article/f44f59de63d243479023e2433fb7a80e
Autor:
Reem Mousa, Taghreed Hidmi, Sergei Pomyalov, Shifra Lansky, Lareen Khouri, Deborah E. Shalev, Gil Shoham, Norman Metanis
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-9 (2021)
Hirudin is a widely studied model for folding of disulfide-rich proteins, which folds through a slow pathway with highly heterogeneous intermediates and scrambled isomers before it reaches its native state. Here the effect of native and non-native di
Externí odkaz:
https://doaj.org/article/90ff74c53b084ca3a7d24d11009d7db6
Autor:
Smadar Shulami, Valery Belakhov, R. Salama, Timor Baasov, Shifra Lansky, Arie Zehavi, Gil Shoham, Yuval Shoham
Publikováno v:
Journal of Biological Chemistry. 295:10766-10780
Strains of the Gram-positive, thermophilic bacterium Geobacillus stearothermophilus possess elaborate systems for the utilization of hemicellulolytic polysaccharides, including xylan, arabinan, and galactan. These systems have been studied extensivel
Autor:
Deborah E. Shalev, Reem Mousa, Gil Shoham, Sergei Pomyalov, Lareen Khouri, Shifra Lansky, Taghreed Hidmi, Norman Metanis
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-9 (2021)
The oxidative folding of proteins has been studied for over sixty years, providing critical insight into protein folding mechanisms. A well-known folding model for many disulfide-rich proteins is that of hirudin. Hirudin, the most potent natural inhi
Autor:
Smadar Shulami, Noa Lavid, Yuval Shoham, Gil Shoham, Saumik Sen, R. Salama, Igor Schapiro, Shifra Lansky
Publikováno v:
Journal of molecular biology. 432(7)
ABC importers are membrane proteins responsible for the transport of nutrients into the cells of prokaryotes. Although the structures of ABC importers vary, all contain four conserved domains: two nucleotide-binding domains (NBDs), which bind and hyd
Autor:
Deborah E. Shalev, Shifra Lansky, Nischay K. Rege, Michael A. Weiss, Norman Metanis, Gil Shoham, Orit Weil‐Ktorza
Publikováno v:
Chemistry
Insulin analogues, mainstays in the modern treatment of diabetes mellitus, exemplify the utility of protein engineering in molecular pharmacology. Whereas chemical syntheses of the individual A and B chains were accomplished in the early 1960s, their
Protein oligomerization contributes significantly to the stability and function of enzymes, and the interacting interfaces that create the oligomers are expected to be conserved. The acetyl-xylo-oligosaccharide esterase, Axe2, from the thermophilic b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9b595f307d4d134b96b5a8e872886a
https://doi.org/10.1101/466904
https://doi.org/10.1101/466904
Publikováno v:
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 222
FTIR and NMR spectra were measured in parallel for specific two-components mixtures of various proteins with different sugar molecules, such as arabinose, glucose, and sucrose. In the FTIR spectra of arabinose with some of these proteins, the bands a
Publikováno v:
'Chemical Science ', vol: 9, pages: 4814-4820 (2018)
Bovine pancreatic trypsin inhibitor (BPTI) is a 58-residue protein that is stabilized by three disulfide bonds at positions 5–55, 14–38 and 30–51. Widely studied for about 50 years, BPTI represents a folding model for many disulfide-rich protei
Publikováno v:
The FEBS journal. 284(22)
6-phospho-β-glucosidases and 6-phospho-β-galactosidases are enzymes that hydrolyze the β-glycosidic bond between a terminal non-reducing glucose-6-phosphate (Glc6P) or galactose-6-phosphate (Gal6P), respectively, and other organic molecules. Gan1D