Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Gil Loewenthal"'
Autor:
Jair Bar, Raya Leibowitz, Niels Reinmuth, Astrid Ammendola, Eyal Jacob, Mor Moskovitz, Adva Levy-Barda, Michal Lotem, Rivka Katsenelson, Abed Agbarya, Mahmoud Abu-Amna, Maya Gottfried, Tatiana Harkovsky, Ido Wolf, Ella Tepper, Gil Loewenthal, Ben Yellin, Yehuda Brody, Nili Dahan, Maya Yanko, Coren Lahav, Michal Harel, Shani Raveh Shoval, Yehonatan Elon, Itamar Sela, Adam P. Dicker, Yuval Shaked
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionImmune checkpoint inhibitors have made a paradigm shift in the treatment of non-small cell lung cancer (NSCLC). However, clinical response varies widely and robust predictive biomarkers for patient stratification are lacking. Here, we cha
Externí odkaz:
https://doaj.org/article/926af04f4d0440e18244af89ddf7f699
Publikováno v:
Open Biology, Vol 12, Iss 12 (2022)
Insertions and deletions (indels) of short DNA segments are common evolutionary events. Numerous studies showed that deletions occur more often than insertions in both prokaryotes and eukaryotes. It raises the question why neutral sequences are not e
Externí odkaz:
https://doaj.org/article/895c3192c83149f99bb5781647946285
Autor:
Gil Loewenthal, Shiran Abadi, Oren Avram, Keren Halabi, Noa Ecker, Natan Nagar, Itay Mayrose, Tal Pupko
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 11, Pp 1-8 (2020)
Abstract The rapid spread of SARS‐CoV‐2 and its threat to health systems worldwide have led governments to take acute actions to enforce social distancing. Previous studies used complex epidemiological models to quantify the effect of lockdown po
Externí odkaz:
https://doaj.org/article/b4ed8fd0f3df49e0937ba6a2167da732
Autor:
Natan Nagar, Noa Ecker, Gil Loewenthal, Oren Avram, Daniella Ben-Meir, Dvora Biran, Eliora Ron, Tal Pupko
Publikováno v:
mSystems, Vol 6, Iss 1 (2021)
ABSTRACT Degradation of intracellular proteins in Gram-negative bacteria regulates various cellular processes and serves as a quality control mechanism by eliminating damaged proteins. To understand what causes the proteolytic machinery of the cell t
Externí odkaz:
https://doaj.org/article/14a68527806f4b45bf2bac5665f46503
Autor:
Tal Pupko, Omer Israeli, Oren Avram, Itay Mayrose, Dana Azouri, Elya Wygoda, Alon Itzkovitch, Reed A. Cartwright, Asher Moshe, Gil Loewenthal, Dana Rapoport
Publikováno v:
Molecular Biology and Evolution
Insertions and deletions (indels) are common molecular evolutionary events. However, probabilistic models for indel evolution are under-developed due to their computational complexity. Here, we introduce several improvements to indel modeling: 1) Whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e42f965c6bf93a46b291766d5b9009d
https://doi.org/10.1093/molbev/msab266
https://doi.org/10.1093/molbev/msab266
Autor:
Asher Moshe, Elya Wygoda, Noa Ecker, Gil Loewenthal, Oren Avram, Omer Israeli, Einat Hazkani-Covo, Itsik Pe’er, Tal Pupko
Publikováno v:
Molecular biology and evolution, vol 39, iss 11
The inference of genome rearrangement events has been extensively studied, as they play a major role in molecular evolution. However, probabilistic evolutionary models that explicitly imitate the evolutionary dynamics of such events, as well as metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b54ccc77fabc16f1b907993e625a01
https://pubmed.ncbi.nlm.nih.gov/36282896
https://pubmed.ncbi.nlm.nih.gov/36282896
Autor:
Edo Dotan, Yonatan Belinkov, Oren Avram, Elya Wygoda, Noa Ecker, Michael Alburquerque, Omri Keren, Gil Loewenthal, Tal Pupko
The sequence alignment problem is one of the most fundamental problems in bioinformatics and a plethora of methods were devised to tackle it. Here we introduce BetaAlign, a novel methodology for aligning sequences using a natural language processing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4483c70523f5cc548262294d2d8a8c00
https://doi.org/10.1101/2022.07.22.501063
https://doi.org/10.1101/2022.07.22.501063
Publikováno v:
Journal of Molecular Biology. :168155
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::437ffa5211af2eb76218dd00a14dd3bb
https://doi.org/10.1016/j.jmb.2023.168155
https://doi.org/10.1016/j.jmb.2023.168155
Autor:
Noa Ecker, Tal Pupko, Eliora Z. Ron, Daniella Ben-Meir, Oren Avram, Gil Loewenthal, Natan Nagar, Dvora Biran
Publikováno v:
mSystems
mSystems, Vol 6, Iss 1 (2021)
mSystems, Vol 6, Iss 1 (2021)
Bacteria use protein degradation to control proliferation, dispose of misfolded proteins, and adapt to physiological and environmental shifts, but the factors that dictate which proteins are prone to degradation are mostly unknown. In this study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c86098682a313f1f03415a2da64ddd
https://doi.org/10.1128/msystems.01296-20
https://doi.org/10.1128/msystems.01296-20
Autor:
Itay Mayrose, Noa Ecker, Shiran Abadi, Natan Nagar, Keren Halabi, Gil Loewenthal, Tal Pupko, Oren Avram
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 12, Iss 11, Pp n/a-n/a (2020)
EMBO Molecular Medicine, Vol 12, Iss 11, Pp n/a-n/a (2020)
The rapid spread of SARS‐CoV‐2 and its threat to health systems worldwide have led governments to take acute actions to enforce social distancing. Previous studies used complex epidemiological models to quantify the effect of lockdown policies on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcae5430c08cfb1a36d26608759e9a49
https://doi.org/10.15252/emmm.202013171
https://doi.org/10.15252/emmm.202013171