Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Gil Costas"'
Publikováno v:
Surgeries, Vol 3, Iss 3, Pp 192-202 (2022)
The use of large animal models in the preclinical setting has expanded and become increasingly valuable for evaluating the safety and efficacy of new therapies and devices. Here, we report normal hemodynamic values, including aortic and pulmonary blo
Externí odkaz:
https://doaj.org/article/73d9648aedb54a90854f9d1a7c474ff5
Autor:
Gil Costas, Taylor Spangler, Luiz C. Sampaio, Abdelmotagaly Elgalad, Chen Chen, Frank Yeong-Sung Lin, P. Alex Smith, J. L. Conger, Kelly M. Handy, Yaxin Wang
Publikováno v:
EMBC
Left ventricular assist devices (LVADs) are used to treat patients with severe (New York Heart Association class IV) heart failure. Thrombosis and bleeding are severe LVAD-related complications; thus, an effective anticoagulation regimen is crucial f
Autor:
Gil Costas, Steven M. Parnis, Sarah Beathard, Jo Anna Winkler, O. H. Frazier, Jeff L. Conger, William E. Cohn
Publikováno v:
ASAIO Journal. 60:15-18
We evaluated the effects of steady state flow and perfusion on end-organ function in a long-term calf model. The animal received a continuous-flow total artificial heart (CFTAH) that we created from two axial-flow ventricular assist devices. Pump flo
The miniaturized pediatric continuous-flow device: Preclinical assessment in the chronic sheep model
Autor:
John Teal, Sarah Burki, Taylor Spangler, Kurt A. Dasse, William E. Cohn, Iki Adachi, Charles D. Fraser, J. Timothy Baldwin, Gil Costas, M. Patricia Massicotte, David Horne, Robert Jarvik, Jeff L. Conger
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 154(1)
Background The Infant Jarvik 2015 is an implantable axial-flow ventricular assist device (VAD) that has undergone the major evolutionary design modifications to improve hemocompatibility. This study was conducted in anticipation of data submission to
Autor:
Denise Byler, Murat Sargin, Branislav Radovancevic, D Tamez, Vijaykumar Surendrakant Patel, Gil Costas, Egemen Tuzun, Dong Liu, O.H. Frazier
Publikováno v:
Shock. 30:675-679
To examine the use of mechanical cardiac assist devices in prolonged hemorrhagic shock lasting up to 120 min. We induced hemorrhagic shock in anesthetized calves that were then treated 30 or 120 min later with either conventional fluid and blood resu
Autor:
Egemen Tuzun, Gil Costas, Jeff L. Conger, Jo Anna Winkler, O.H. Frazier, Nicholas L. Gilbert, William E. Cohn
Publikováno v:
ASAIO journal (American Society for Artificial Internal Organs : 1992). 55(5)
Chronic ventilatory support may be required for survival after total artificial heart (TAH) implantation in calves. However, prolonged or repeated intubation may negatively affect a calf's ability to eat, drink, ruminate, and stand after surgery. To
Publikováno v:
Comparative medicine. 55(3)
The circadian temperature rhythm (CTR) profile holds promise for monitoring the domestic pig's responses to stress and illness. In the present study we quantified the CTR profile of nine growing-finishing swine using a time-series, small-group design
Publikováno v:
Comparative medicine. 54(1)
A porcine adult ICU model would be useful for several avenues of investigation relevant to the care of critically ill patients. The purpose of the experiments reported here was to test the feasibility of such a model, using healthy swine. Swine (n =
Publikováno v:
ASAIO Journal. 52:53A
Autor:
Egemen Tuzun, J. L. Conger, Gil Costas, Jo Anna Winkler, B. Radovancevic, O. H. Frazier, W D Cohn, Courtney J. Gemmato
Publikováno v:
ASAIO Journal. 52:42A