Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Gil Blander"'
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0293631 (2023)
Exercise is effective toward delaying or preventing chronic disease, with a large body of evidence supporting its effectiveness. However, less is known about the specific healthspan-promoting effects of exercise on blood biomarkers in the disease-fre
Externí odkaz:
https://doaj.org/article/5a8599f00e8e4ba8b2785bf2bc99fd3c
Autor:
Ashley Reaver, Susan Hewlings, Kenneth Westerman, Gil Blander, Thorsten Schmeller, Marianne Heer, Dietrich Rein
Publikováno v:
Nutrients, Vol 11, Iss 9, p 2108 (2019)
Elevated blood concentration of low-density lipoprotein cholesterol (LDLc) is a primary risk factor for developing cardiovascular disease. Lifestyle interventions including an increase in dietary phytosterols as well as medications have proven effect
Externí odkaz:
https://doaj.org/article/ce3ee344584c47d99fd98f3f1a407ecb
Autor:
Renée Deehan, Pia Maerz-Weiss, Natalie L Catlett, Guido Steiner, Ben Wong, Matthew B Wright, Gil Blander, Keith O Elliston, William Ladd, Maria Bobadilla, Jacques Mizrahi, Carolina Haefliger, Alan Edgar
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35012 (2012)
To compare the molecular and biologic signatures of a balanced dual peroxisome proliferator-activated receptor (PPAR)-α/γ agonist, aleglitazar, with tesaglitazar (a dual PPAR-α/γ agonist) or a combination of pioglitazone (Pio; PPAR-γ agonist) an
Externí odkaz:
https://doaj.org/article/475a8cda13934ba29121906ff106164e
Autor:
Ron Firestein, Gil Blander, Shaday Michan, Philipp Oberdoerffer, Shuji Ogino, Jennifer Campbell, Anupama Bhimavarapu, Sandra Luikenhuis, Rafael de Cabo, Charles Fuchs, William C Hahn, Leonard P Guarente, David A Sinclair
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e2020 (2008)
Numerous longevity genes have been discovered in model organisms and altering their function results in prolonged lifespan. In mammals, some have speculated that any health benefits derived from manipulating these same pathways might be offset by inc
Externí odkaz:
https://doaj.org/article/6d2383a243f347e2ac76fe3716876994
Publikováno v:
Current Developments in Nutrition
Since next generation sequencing facilitated high-throughput and cost-efficient genomics analyses, the human gut metagenome has become an emerging frontier to explore toward precision nutrition. Significant progress has been made in identifying gut m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb3f08e84f9c159eead3f49534617bc
https://pubmed.ncbi.nlm.nih.gov/34514287
https://pubmed.ncbi.nlm.nih.gov/34514287
Autor:
Thorsten Schmeller, Marianne Heer, Dietrich Rein, Susan Hewlings, Kenneth Westerman, Gil Blander, Ashley Reaver
Publikováno v:
Nutrients
Nutrients, Vol 11, Iss 9, p 2108 (2019)
Volume 11
Issue 9
Nutrients, Vol 11, Iss 9, p 2108 (2019)
Volume 11
Issue 9
Elevated blood concentration of low-density lipoprotein cholesterol (LDLc) is a primary risk factor for developing cardiovascular disease. Lifestyle interventions including an increase in dietary phytosterols as well as medications have proven effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec127352a4b3e9d567e4df4fae11faf
https://pubmed.ncbi.nlm.nih.gov/31491873
https://pubmed.ncbi.nlm.nih.gov/31491873
Autor:
Margaret Ploch, Gil Blander, Jeffrey B. Blumberg, Catherine Roy, Kenneth Westerman, Erin Sharoni, David L. Katz, Bartek Nogal, David A. Sinclair, Ashley Reaver
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
The trend toward personalized approaches to health and medicine has resulted in a need to collect high-dimensional datasets on individuals from a wide variety of populations, in order to generate customized intervention strategies. However, it is not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298a3de3be927c5cc5cb1f250a1b25d6
http://europepmc.org/articles/PMC6168584
http://europepmc.org/articles/PMC6168584
Autor:
Gil Blander
Publikováno v:
Current Developments in Nutrition. 3:nzz034.P10-130
OBJECTIVES: A longitudinal analysis was conducted on blood biomarker data from 1032 generally healthy individuals who used an automated, web-based personalized nutrition and lifestyle platform. METHODS: Combining the power of automation with the conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f72a8ff06df3cc3a4b2872d1ea06c3
https://doi.org/10.1093/cdn/nzz034.p10-130-19
https://doi.org/10.1093/cdn/nzz034.p10-130-19
Autor:
Gil Blander, Keith O. Elliston, Daniel H. Maes, Thomas Mammone, M Matsui, Leonard Guarente, Anupama Bhimavarapu, Christian Reich, Joseph Loureiro
Publikováno v:
Journal of Investigative Dermatology. 129(1):41-49
Sir2 regulates lifespan in model organisms, which has stimulated interest in understanding human Sir2 homolog functions. The human Sir2 gene family comprises seven members (SIRT1-SIRT7). SIRT1, the human ortholog of the yeast Sir2 by closest sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6afe1ab64b392054e3b10bac037f5b74
Autor:
Gil Blander, Leonard Guarente
Publikováno v:
Annual Review of Biochemistry. 73:417-435
▪ Abstract The yeast SIR protein complex has been implicated in transcription silencing and suppression of recombination. The Sir complex represses transcription at telomeres, mating-type loci, and ribosomal DNA. Unlike SIR3 and SIR4, the SIR2 gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c880c3a82587a34dfa3f460339709a78
https://doi.org/10.1146/annurev.biochem.73.011303.073651
https://doi.org/10.1146/annurev.biochem.73.011303.073651