Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Gil Arbel"'
Autor:
Claire Hopton, Anke J. Tijsen, Leonid Maizels, Gil Arbel, Amira Gepstein, Nicola Bates, Benjamin Brown, Irit Huber, Susan J. Kimber, William G. Newman, Luigi Venetucci, Lior Gepstein
Publikováno v:
Physiological Reports, Vol 10, Iss 8, Pp n/a-n/a (2022)
Abstract Heterozygous missense variants of the cardiac ryanodine receptor gene (RYR2) cause catecholaminergic polymorphic ventricular tachycardia (CPVT). These missense variants of RYR2 result in a gain of function of the ryanodine receptors, charact
Externí odkaz:
https://doaj.org/article/0a54c9a572d34f8e990a65b6a055122d
Autor:
Amit Gruber, Oded Edri, Shany Glatstein, Idit Goldfracht, Irit Huber, Gil Arbel, Amira Gepstein, Snizhanna Chorna, Lior Gepstein
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 4 (2022)
Background Optogenetics, using light‐sensitive proteins, emerged as a unique experimental paradigm to modulate cardiac excitability. We aimed to develop high‐resolution optogenetic approaches to modulate electrical activity in 2‐ and 3‐dimens
Externí odkaz:
https://doaj.org/article/d8ea8164a31c428d81568856b16eba36
Autor:
Amit Gruber, Oded Edri, Irit Huber, Gil Arbel, Amira Gepstein, Assad Shiti, Naim Shaheen, Snizhana Chorna, Michal Landesberg, Lior Gepstein
Publikováno v:
JCI Insight, Vol 6, Iss 11 (2021)
Abnormal action potential (AP) properties, as occurs in long or short QT syndromes (LQTS and SQTS, respectively), can cause life-threatening arrhythmias. Optogenetics strategies, utilizing light-sensitive proteins, have emerged as experimental platfo
Externí odkaz:
https://doaj.org/article/0db7bf8098d545debc0509695a72f315
Autor:
Rami Shinnawi, Irit Huber, Leonid Maizels, Naim Shaheen, Amira Gepstein, Gil Arbel, Anke J. Tijsen, Lior Gepstein
Publikováno v:
Stem Cell Reports, Vol 5, Iss 4, Pp 582-596 (2015)
The advent of the human-induced pluripotent stem cell (hiPSC) technology has transformed biomedical research, providing new tools for human disease modeling, drug development, and regenerative medicine. To fulfill its unique potential in the cardiova
Externí odkaz:
https://doaj.org/article/a4585caa049549da976fdd00d85ae58c
Autor:
Ilanit Itzhaki, Sophia Rapoport, Irit Huber, Itzhak Mizrahi, Limor Zwi-Dantsis, Gil Arbel, Jackie Schiller, Lior Gepstein
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18037 (2011)
BACKGROUND: The ability to establish human induced pluripotent stem cells (hiPSCs) by reprogramming of adult fibroblasts and to coax their differentiation into cardiomyocytes opens unique opportunities for cardiovascular regenerative and personalized
Externí odkaz:
https://doaj.org/article/b7f9715c6dee4c53850ff281d8848694
Autor:
Yehuda Wexler, Matteo Ghiringhelli, Naim Shaheen, Shany Glatstein, Irit Huber, Oded Edri, Yousef Abboud, Michal Landesberg, Daniel Shiff, Gil Arbel, Lior Gepstein
Publikováno v:
Circulation Research. 132:645-647
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ce6fa149194f1bac1305ef767988fe6
https://doi.org/10.1161/circresaha.122.322041
https://doi.org/10.1161/circresaha.122.322041
Autor:
Caroline Bashai, Noam Kazma, Idan Haiim, Yaara Libai, Anastasia Nevo, Gil Arbel, Amira Gepstein, Oren Caspi
Publikováno v:
Circulation. 144
Cardio-oncology in a dish: cardiovascular tissueengineering strategies for modeling cancer therapyrelated cardiac dysfunction.Over the recent years, there was a robust proliferation of oncological therapies leading to asignificant reduction in cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a26958a148b6694c17e61d4a64c3e1d
https://doi.org/10.1161/circ.144.suppl_1.13887
https://doi.org/10.1161/circ.144.suppl_1.13887
Autor:
Gil Arbel, E Heller, Irit Huber, Michal Landesberg, Elad Maor, Amira Gepstein, L Maizels, Lior Gepstein
Publikováno v:
European Heart Journal. 42
Background Cardiac electroporation is a promising novel non-thermal ablation method, gaining significant interest with recent first-in-man data suggesting effective cardiac lesion generation with no collateral damage. Nevertheless, significant knowle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::980c953a00b082145d81946f4412e78e
https://doi.org/10.1093/eurheartj/ehab724.3215
https://doi.org/10.1093/eurheartj/ehab724.3215
Autor:
Ekaterina Kovalev, Lior Gepstein, Naim Shaheen, Amira Gepstein, Marcelle Machluf, Rami Shinnawi, Malte Tiburcy, Yael Efraim, Wolfram H. Zimmermann, Idit Goldfracht, Gil Arbel, Irit Huber
Publikováno v:
Acta Biomaterialia
Cardiac tissue engineering provides unique opportunities for cardiovascular disease modeling, drug testing, and regenerative medicine applications. To recapitulate human heart tissue, we combined human induced pluripotent stem cell-derived cardiomyoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03980c3ceedf0d88057d1d428fd5250a
https://doi.org/10.1016/j.actbio.2019.05.016
https://doi.org/10.1016/j.actbio.2019.05.016
Autor:
Matteo, Ghiringhelli, Yousef, Abboud, Snizhanna V, Chorna, Irit, Huber, Gil, Arbel, Amira, Gepstein, Georgia, Pennarossa, Tiziana A L, Brevini, Lior, Gepstein
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2273
Tissue engineering provides unique opportunities for disease modeling, drug testing, and regenerative medicine applications. The use of cell-seeded scaffolds to promote tissue development is the hallmark of the tissue engineering. Among the different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::90ebd05728131aee419503afbecb309b
https://pubmed.ncbi.nlm.nih.gov/33604848
https://pubmed.ncbi.nlm.nih.gov/33604848