Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Gijsbert C. de Gast"'
Publikováno v:
Urologia Internationalis. 80:367-371
Aims: To assess the strategy of using an absence of progression at metastatic sites following initial cytokine therapy outcome as a selection criterion for nephrectomy in patients with synchronous metastatic renal carcinoma and an intermediate progno
Autor:
Axel Bex, Martijn R. Meijerink, Alfons J.M. van den Eertwegh, John B. A. G. Haanen, Astrid A.M. van der Veldt, Gijsbert C. de Gast, Epie Boven
Publikováno v:
Clinical Cancer Research, 14(8), 2431-2436. American Association for Cancer Research Inc.
van der Veldt, A A M, Meijerink, M R, van den Eertwegh, A J M, Bex, A, de Gast, G C, Haanen, J B & Boven, E 2008, ' Sunitinib for treatment of advanced renal cell cancer: primary tumor response ', Clinical Cancer Research, vol. 14, no. 8, pp. 2431-2436 . https://doi.org/10.1158/1078-0432.CCR-07-4089
van der Veldt, A A M, Meijerink, M R, van den Eertwegh, A J M, Bex, A, de Gast, G C, Haanen, J B & Boven, E 2008, ' Sunitinib for treatment of advanced renal cell cancer: primary tumor response ', Clinical Cancer Research, vol. 14, no. 8, pp. 2431-2436 . https://doi.org/10.1158/1078-0432.CCR-07-4089
Purpose: Nephrectomy before immunotherapy in patients with metastatic renal cell cancer (RCC) will improve patient outcome. In addition, the primary tumor is known to be refractory to cytokines. Sunitinib is now approved for treatment of advanced RCC
Autor:
Mehtap G. Cinar, Seung Ki Min, Magnus Von Heland, C. Acar, Steffen Weikert, Miguel Srougi, Jason John, S. Sozen, Ulderico Parente, Yu-Hsien Su, Kenji Mizutani, Myeong Ok Kim, Matthew Perry, Kurt Miller, Chien-Jen Chen, Flavio Trigo-Rocha, Yung-Chiong Chow, Catherine Whitbeck, Yung-Kai Huang, J. Dvořáček, Stephan Kruck, Gijsbert C. de Gast, V. Soukup, Joerg Hennenlotter, Tim O’Brien, Simon Horenblas, Robert E. Leggett, Martin Schostak, Seiji Matsumoto, S. Mićić, Ayten Ariöz, Saniye Benli, D. Milovanović, Emel Ege, Chi-Jung Chung, Steven K. Huang, Hae Young Lee, B.E. Akkas, Akifumi Higurashi, L. Zámečník, M. Babjuk, Ursula Kuehs, J. Dušková, Toshiro Kamata, Ömer Ceran, Nobuaki Ohto, Wen-Chou Lin, Alessandro Sciarra, Belgin Akin, Chun-Jen Huang, S.E. Allen, A. Erdem Canda, Paulo Tadeu Dib, Burak Turna, Roberto Passariello, M. Ihsan Karaman, Jong Yoon Bahk, Frank Christoph, Eva Koch, Stone Yang, I. Sen, Timo Joensuu, Alfarone Andrea, Oliver W. Hakenberg, Kamile Altuntuğ, Arnulf Stenzl, M.T. Kitapci, Markus A. Kuczyk, M. Szakáczová, M. Pešl, Axel Bex, Franco Di Silverio, Hung-Jen Shih, Yu-Mei Hsueh, Stefan Hinz, M. Oguz Sahin, Kiyohide Fushimi, John B. A. G. Haanen, Moon Seok Park, Robert M. Levin, Hitendra R.H. Patel, Cristiano Mendes Gomes, Bong Chul Chung, Carsten Kempkensteffen, Hui-Ju Tsai, Jeong-Hee Lee, M. Stojadinović, Allen W. Chiu, Mo-Hsiung Yang, Takao Ikeda, Çağatay Nuhoğlu, Kursat Bora Carman, Florry A. Vyth-Dreese, Mark Schrader, Cevdet Kaya, Perikles Simon, Yeong-Shiau Pu, Ilker Akyol, Valeria Panebianco, Axel S. Merseburger
Publikováno v:
Urologia Internationalis. 80:I-VI
Publikováno v:
Cancer. 109:306-312
BACKGROUND. The efficacy of radiotherapy (RT) in patients who have brain metastases from melanoma is limited. In this study, the authors evaluated the efficacy of treatment with temozolomide in patients with metastatic melanoma, including small brain
Autor:
Gijsbert C. de Gast, Ton N. Schumacher, H. Mallo, Harm van Tinteren, Pauline Weder, Sjoerd G. Elias, Maarten P.W. Gallee, Monique van Oijen, J. J. Sein, Adriaan Bins, John B. A. G. Haanen
Publikováno v:
Clinical Cancer Research. 10:4754-4760
Cytotoxic T-cell immunity directed against melanosomal differentiation antigens is arguably the best-studied and most prevalent form of tumor-specific T-cell immunity in humans. Despite this, the role of T-cell responses directed against melanosomal
Publikováno v:
Technology in Cancer Research & Treatment. 2:205-210
Multimodality treatment of metastatic renal cell carcinoma with immunotherapy and cytoreductive surgery is controversial. Especially the benefit of removing asymptomatic primary tumors in synchronous metastatic renal cell cancer has been debated sinc
Publikováno v:
Cancer Immunology, Immunotherapy. 51:630-636
A regimen of sequential chemoimmunotherapy (SCIT) was studied in a phase I/II study to analyze toxicity, anti-tumor and immunomodulatory effects in patients with previously untreated metastatic cutaneous melanoma. Treatment consisted of dacarbazine (
Publikováno v:
Immunology today. 8(7-8)
Graft-versus-host disease (GVHD), a major complication of bone marrow transplantation, often occurs despite genotypic HLA identity between patient and donor. Here, Gijsbert de Gast and his colleagues suggest that pretransplant cytoreductive therapy r
Autor:
Leo F. Verdonck, Floortje L. Kessler, René A. W. van Lier, Simone A. E. Stadhouders-Keet, Henny G. Otten, Gijsbert C. de Gast, Astrid M. C. van Dijk
Publikováno v:
British Journal of Haematology. 111:791-796
Graft-versus-host-disease (GVHD) remains a major problem following allogeneic bone marrow transplantation (BMT) and manifests itself mainly by damage to epithelial cells of the skin, gut and bile ducts. Reliable tests to predict GVHD are lacking. We
Autor:
Astrid M. C. van Dijk, Floortje L. Kessler, Leo F. Verdonck, Simone A. E. Stadhouders-Keet, Rene A. W. van Lier, Gijsbert C. de Gast, Henny G. Otten
Publikováno v:
British Journal of Haematology. 111:791-796