Zobrazeno 1 - 10
of 398
pro vyhledávání: '"Gijsbert A, van der Marel"'
Autor:
Johannes Gregor Matthias Rack, Qiang Liu, Valentina Zorzini, Jim Voorneveld, Antonio Ariza, Kourosh Honarmand Ebrahimi, Julia M. Reber, Sarah C. Krassnig, Dragana Ahel, Gijsbert A. van der Marel, Aswin Mangerich, James S. O. McCullagh, Dmitri V. Filippov, Ivan Ahel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
PARG and ARH3 are the main hydrolases to reverse serine poly(ADP-ribosylation) yet their activities in the process differ. Here, the authors synthesise linear and branched poly(ADP-ribose) molecules, perform structure-function analysis and elucidate
Externí odkaz:
https://doaj.org/article/4bbd22b00672441db09292221ae3ea22
Autor:
Jacopo Enotarpi, Marta Tontini, Cristiana Balocchi, Daan van der Es, Ludovic Auberger, Evita Balducci, Filippo Carboni, Daniela Proietti, Daniele Casini, Dmitri V. Filippov, Hermen S. Overkleeft, Gijsbert A. van der Marel, Cinzia Colombo, Maria Rosaria Romano, Francesco Berti, Paolo Costantino, Jeroen D. C. Codeé, Luigi Lay, Roberto Adamo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
The Neisseria meningitidis serogroup A capsular polysaccharide (MenA CPS) is a component of commercial vaccines, but is unstable. Here, the authors generate glycomimetic oligomers that demonstrate higher stability than their natural counterparts and
Externí odkaz:
https://doaj.org/article/1d2c58955e994faaa3143dcfc9de2b58
Autor:
Thomas Hansen, Hidde Elferink, Jacob M. A. van Hengst, Kas J. Houthuijs, Wouter A. Remmerswaal, Alexandra Kromm, Giel Berden, Stefan van der Vorm, Anouk M. Rijs, Hermen S. Overkleeft, Dmitri V. Filippov, Floris P. J. T. Rutjes, Gijsbert A. van der Marel, Jonathan Martens, Jos Oomens, Jeroen D. C. Codée, Thomas J. Boltje
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Dioxolenium ion intermediates formed from remote positions are hypothesized to direct stereoselective glycosylations. Herein we combine infrared ion spectroscopy, DFT calculations and synthetic work to characterize and study these dioxolenium ions an
Externí odkaz:
https://doaj.org/article/6ec49b5d3eff4a6ea8a8b5a70ecb1904
Autor:
Yongzhen Zhang, Liming Wang, Herman S. Overkleeft, Gijsbert A. van der Marel, Jeroen D. C. Codée
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Pseudomonas aeruginosa, a pathogenic Gram-negative bacterium for which currently antibiotic resistance is posing a significant problem and for which no vaccines are available, protects itself by the formation of a biofilm. The Pel polysaccharide, a c
Externí odkaz:
https://doaj.org/article/b28a7ef3705240a6953af93c23630ccc
Autor:
Qingju Zhang, Ana Gimeno, Darielys Santana, Zhen Wang, Yury Valdés-Balbin, Laura M. Rodríguez-Noda, Thomas Hansen, Li Kong, Mengjie Shen, Herman S. Overkleeft, Vicente Vérez-Bencomo, Gijsbert A. van der Marel, Jesús Jiménez-Barbero, Fabrizio Chiodo, Jeroen D. C. Codée
Publikováno v:
ACS Central Science, Vol 5, Iss 8, Pp 1407-1416 (2019)
Externí odkaz:
https://doaj.org/article/41e2d2b27ba74e98b4006b2607fb4291
Autor:
Sybrin P. Schröder, Casper de Boer, Nicholas G. S. McGregor, Rhianna J. Rowland, Olga Moroz, Elena Blagova, Jos Reijngoud, Mark Arentshorst, David Osborn, Marc D. Morant, Eric Abbate, Mary A. Stringer, Kristian B. R. M. Krogh, Lluís Raich, Carme Rovira, Jean-Guy Berrin, Gilles P. van Wezel, Arthur F. J. Ram, Bogdan I. Florea, Gijsbert A. van der Marel, Jeroen D. C. Codée, Keith S. Wilson, Liang Wu, Gideon J. Davies, Herman S. Overkleeft
Publikováno v:
ACS Central Science, Vol 5, Iss 6, Pp 1067-1078 (2019)
Externí odkaz:
https://doaj.org/article/f864bdc8d62e4812a1bdf17abbce08b0
Autor:
Thomas Hansen, Ludivine Lebedel, Wouter A. Remmerswaal, Stefan van der Vorm, Dennis P. A. Wander, Mark Somers, Herman S. Overkleeft, Dmitri V. Filippov, Jérôme Désiré, Agnès Mingot, Yves Bleriot, Gijsbert A. van der Marel, Sebastien Thibaudeau, Jeroen D. C. Codée
Publikováno v:
ACS Central Science, Vol 5, Iss 5, Pp 781-788 (2019)
Externí odkaz:
https://doaj.org/article/5fe9ceb3d2224603acb1f3753c3e07c3
Autor:
Gijs G. Zom, Marian M. J. H. P. Willems, Selina Khan, Tetje C. van der Sluis, Jan Willem Kleinovink, Marcel G. M. Camps, Gijsbert A. van der Marel, Dmitri V. Filippov, Cornelis J. M. Melief, Ferry Ossendorp
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-13 (2018)
Abstract Background Ligands for the Toll-like receptor (TLR) family can induce activation of cells of the innate immune system and are widely studied for their potential to enhance adaptive immunity. Conjugation of TLR2-ligand Pam3CSK4 to synthetic l
Externí odkaz:
https://doaj.org/article/709a690ddcf245d583864fadeb597229
Autor:
Jacob M. A. van Hengst, Rik J. C. Hellemons, Wouter A. Remmerswaal, Koen N. A. van de Vrande, Thomas Hansen, Stefan van der Vorm, Hermen S. Overkleeft, Gijsbert A. van der Marel, Jeroen D. C. Codée
Publikováno v:
Chemical Science, 14(6), 1532-1542. Royal Society of Chemistry
van Hengst, J M A, Hellemons, R J C, Remmerswaal, W A, van de Vrande, K N A, Hansen, T, van der Vorm, S, Overkleeft, H S, van der Marel, G A & Codée, J D C 2023, ' Mapping the effect of configuration and protecting group pattern on glycosyl acceptor reactivity ', Chemical Science, vol. 14, no. 6, pp. 1532-1542 . https://doi.org/10.1039/d2sc06139b
van Hengst, J M A, Hellemons, R J C, Remmerswaal, W A, van de Vrande, K N A, Hansen, T, van der Vorm, S, Overkleeft, H S, van der Marel, G A & Codée, J D C 2023, ' Mapping the effect of configuration and protecting group pattern on glycosyl acceptor reactivity ', Chemical Science, vol. 14, no. 6, pp. 1532-1542 . https://doi.org/10.1039/d2sc06139b
The reactivity of the acceptor alcohol can have a tremendous influence on the outcome of a glycosylation reaction, both in terms of yield and stereoselectivity. Through a systematic survey of 67 acceptor alcohols in glycosylation reactions with two g
Autor:
Marta Artola, Liang Wu, Maria J. Ferraz, Chi-Lin Kuo, Lluís Raich, Imogen Z. Breen, Wendy A. Offen, Jeroen D. C. Codée, Gijsbert A. van der Marel, Carme Rovira, Johannes M. F. G. Aerts, Gideon J. Davies, Herman S. Overkleeft
Publikováno v:
ACS Central Science, Vol 3, Iss 7, Pp 784-793 (2017)
Externí odkaz:
https://doaj.org/article/ed80748b307b4500a299decac625948f