Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gijs M.W. van Schijndel"'
Autor:
S. Marieke van Ham, Miranda Dieker, Sonja T. H. M. Kolanowski, Anja ten Brinke, Gijs M.W. van Schijndel, Suzanne N. Lissenberg-Thunnissen
Publikováno v:
Innate immunity, 20(4), 423-430. SAGE Publications Ltd
TLR4 ligation can activate both the MyD88 and the Toll-IL-1 receptor domain-containing adaptor inducing IFN-β (TRIF) signaling route. Whereas MyD88 is generally recognized as a universal adaptor for pro-inflammatory responses, TRIF is mainly thought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8c2c3d7d2344bcb3d88cd34013d985
https://doi.org/10.1177/1753425913498626
https://doi.org/10.1177/1753425913498626
Publikováno v:
Cytotherapy, 18(7), 902-910. Informa Healthcare
Background As initiators of the adaptive immune response, dendritic cells (DCs) can be used for anti-cancer immunotherapy. On addition of proper maturation stimuli DCs mature and produce pro-inflammatory cytokines that skew T cells in the direction n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da85e86b8695d0ba0d5e626d9c9844b
https://pubmed.ncbi.nlm.nih.gov/27209277
https://pubmed.ncbi.nlm.nih.gov/27209277
Autor:
Gijs M.W. van Schijndel, Krista E. van Meijgaarden, Nanette M. Palmer, Veenu Purwaha, Geertje H.A. Westerlaken, Debbie van Baarle, Annemieke Geluk, Kiki Tesselaar, Mireille Toebes, Ton N. Schumacher, Corine Bronke
Publikováno v:
Human Immunology. 66:950-961
In order to detect epitope-specific CD4+ T cells in mycobacterial or viral infections in the context of human class II major histocompatibility complex protein human leukocyte antigen (HLA)-DR3, two HLA-DR3 tetrameric molecules were successfully prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49579eaa451fa4d0b41bdb5a786521d1
https://doi.org/10.1016/j.humimm.2005.06.011
https://doi.org/10.1016/j.humimm.2005.06.011
Autor:
Gijs M.W. van Schijndel, Danita H. Schuurhuis, Reina E. Mebius, Yanling Xiao, Ramon Arens, Kiki Tesselaar, Jannie Borst, René A. W. van Lier
Publikováno v:
Journal of immunology (Baltimore, Md., 170(1), 33-40. American Association of Immunologists
Tesselaar, K, Xiao, Y, Arens, R, van Schijndel, G M W, Schuurhuis, D H, Mebius, R E, Borst, J & van Lier, R A W 2003, ' Expression of the murine CD27 ligand CD70 in vitro and in vivo ', Journal of Immunology, vol. 170, no. 1, pp. 33-40 .
Journal of Immunology, 170(1), 33-40. American Association of Immunologists
Tesselaar, K, Xiao, Y, Arens, R, van Schijndel, G M W, Schuurhuis, D H, Mebius, R E, Borst, J & van Lier, R A W 2003, ' Expression of the murine CD27 ligand CD70 in vitro and in vivo ', Journal of Immunology, vol. 170, no. 1, pp. 33-40 .
Journal of Immunology, 170(1), 33-40. American Association of Immunologists
The interaction between TNFR family member CD27 and its ligand CD70 promotes lymphocyte expansion and effector cell formation. In humans, control of CD27 function is partly regulated by the restricted expression of CD70. We used newly developed mAbs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ba1ba43eb714f688b2c734530d118e
https://doi.org/10.4049/jimmunol.170.1.33
https://doi.org/10.4049/jimmunol.170.1.33
Autor:
Jannie Borst, Paul A. Baars, René A. W. van Lier, Gijs M.W. van Schijndel, Marinus H. J. van Oers, Kiki Tesselaar, Martin van der Valk, Ramon Arens
Publikováno v:
Nature immunology, 4(1), 49-54. Nature Publishing Group
It has been proposed that HIV-1, in addition to directly infecting and killing CD4+ T cells, causes T cell dysfunction and T cell loss by chronic immune activation. We analyzed the effects of chronic immune activation in mice that constitutively expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b250c11e8b19e7e12d6dca19de450b30
https://doi.org/10.1038/ni869
https://doi.org/10.1038/ni869
Autor:
Gijs M.W. van Schijndel, Anja ten Brinke, Sonja T. H. M. Kolanowski, Lathees Sritharan, Suzanne N. Lissenberg-Thunnissen, S. Marieke van Ham
Publikováno v:
Cytotherapy, 16(6), 826-834. Informa Healthcare
Background aims Ex vivo –generated monocyte-derived dendritic cells (DCs) matured with monophosphoryl lipid A (MPLA) and interferon-γ (IFN-γ) can be used as cancer immunotherapy. MPLA/IFN-γ DCs induce Th1 T cell responses and have migratory capa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b239bee138d1c346d63bd9f7aa2e34f2
https://pubmed.ncbi.nlm.nih.gov/24529557
https://pubmed.ncbi.nlm.nih.gov/24529557
Autor:
S. Marieke van Ham, Anouk Zaal, Anja ten Brinke, Gijs M.W. van Schijndel, Diana Wouters, Suzanne N. Lissenberg-Thunnissen
Publikováno v:
Immunobiology, 218(2), 175-80. Urban und Fischer Verlag GmbH und Co. KG
Zaal, A, Lissenberg-Thunnissen, S N, van Schijndel, G, Wouters, D, van Ham, S M & ten Brinke, A 2013, ' Crosstalk between Toll like receptors and C5a receptor in human monocyte derived DCs suppress inflammatory cytokine production ', Immunobiology, vol. 218, no. 2, pp. 175-80 . https://doi.org/10.1016/j.imbio.2012.02.014
Immunobiology, 218(2), 175-180. Urban und Fischer Verlag GmbH und Co. KG
Zaal, A, Lissenberg-Thunnissen, S N, van Schijndel, G, Wouters, D, van Ham, S M & ten Brinke, A 2013, ' Crosstalk between Toll like receptors and C5a receptor in human monocyte derived DCs suppress inflammatory cytokine production ', Immunobiology, vol. 218, no. 2, pp. 175-80 . https://doi.org/10.1016/j.imbio.2012.02.014
Immunobiology, 218(2), 175-180. Urban und Fischer Verlag GmbH und Co. KG
The complement anaphylatoxin, C5a has been implicated in regulation of adaptive immune responses through modulation of APC function as shown mainly in studies in mice. C5a was shown to enhance cytokine production in immature DCs, but the effect of C5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6acb7cdad84bc2d284d741ea342c42e
https://research.vumc.nl/en/publications/233096f8-598e-425b-a47a-49e1c6c4155f
https://research.vumc.nl/en/publications/233096f8-598e-425b-a47a-49e1c6c4155f
Autor:
Tanja D. de Gruijl, Gijs M.W. van Schijndel, Jaap Jan Zwaginga, Remco Visser, Anja ten Brinke, S. Marieke van Ham
Publikováno v:
Cancer Immunology and Immunotherapy, 59(8), 1185-1195. Springer Science and Business Media Deutschland GmbH
ten Brinke, A, van Schijndel, G, Visser, R, de Gruijl, T D, Zwaginga, JJ & van der Ham, S M 2010, ' Monophosphoryl lipid A plus IFN gamma maturation of dendritic cells induces antigen-specific CD8(+) cytotoxic T cells with high cytolytic potential ', Cancer Immunology and Immunotherapy, vol. 59, no. 8, pp. 1185-1195 . https://doi.org/10.1007/s00262-010-0843-z
Cancer Immunology, Immunotherapy, 59(8), 1185-1195
Cancer immunology, immunotherapy, 59(8), 1185-1195. Springer Science and Business Media Deutschland GmbH
ten Brinke, A, van Schijndel, G, Visser, R, de Gruijl, T D, Zwaginga, JJ & van der Ham, S M 2010, ' Monophosphoryl lipid A plus IFN gamma maturation of dendritic cells induces antigen-specific CD8(+) cytotoxic T cells with high cytolytic potential ', Cancer Immunology and Immunotherapy, vol. 59, no. 8, pp. 1185-1195 . https://doi.org/10.1007/s00262-010-0843-z
Cancer Immunology, Immunotherapy, 59(8), 1185-1195
Cancer immunology, immunotherapy, 59(8), 1185-1195. Springer Science and Business Media Deutschland GmbH
Dendritic cells (DCs) are promising antigen presenting cells for cancer treatment. Previously, we showed that the combination of monophosphoryl lipid A (MPLA) with IFN gamma generates mature DCs that produce IL-12 and polarize CD4(+) T cells towards
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9770d0edb826801f031f8471071aef81
https://research.vumc.nl/en/publications/e1e483cf-4886-4405-ae73-ff2b0e9f0617
https://research.vumc.nl/en/publications/e1e483cf-4886-4405-ae73-ff2b0e9f0617
Autor:
Kiki Tesselaar, Ramon Arens, Gijs M.W. van Schijndel, Paul A. Baars, Martin A. van der Valk, Jannie Borst, Marinus H.J. van Oers, René A.W. van Lier
Publikováno v:
Nature Immunology. 4:295-295
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d6eacfba214d3d549f2d2d82bae4252
https://doi.org/10.1038/ni0303-295
https://doi.org/10.1038/ni0303-295
Autor:
Ramon Arens, Gijs M.W. van Schijndel, Marinus H. J. van Oers, Steven T. Pals, Paul Krimpenfort, Jannie Borst, Paul A. Baars, René A. W. van Lier, Kiki Tesselaar, Jenny Hendriks
Publikováno v:
Immunity, 15(5), 801-812. Cell Press
The interaction between the TNF receptor family member CD27 and its ligand CD70 provides a costimulatory signal for T cell expansion. Normally, tightly regulated expression of CD70 ensures the transient availability of this costimulatory signal. Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6073fc127145941e09a8725ad4e4cf84