Technical Perspective for Video Based Assessment of Surgeries in Low-Resource Settings

Autor: Jurre van Kesteren, Leandra A.E. van Goudoever, Amara Conteh, Gijs J.D. van Acker, H. Jaap Bonjer, Håkon A. Bolkan

Publikováno v: Journal of Surgical Education, 80(4), 495-498. Elsevier Inc.
van Kesteren, J, van Goudoever, L A E, Conteh, A, van Acker, G J D, Bonjer, H J & Bolkan, H K A 2023, ' Technical Perspective for Video Based Assessment of Surgeries in Low-Resource Settings ', Journal of Surgical Education, vol. 80, no. 4, pp. 495-498 . https://doi.org/10.1016/j.jsurg.2023.01.003

Objective: Scalable digital learning environments are essential to sustain surgical training programs worldwide. Detailed images of surgeries enriched with educational annotations are vital to train the eyes of the learners. Here, we report a low-cos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369211f83a1941972498f9ee007f449e
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85150057050&origin=inward

Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity

Autor: Lakshmi Bhagat, Ashok K. Saluja, Gijs J.D. Van Acker, Vijay P. Singh, Albert M. Song, Michael L. Steer

Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 283:G794-G800

Intrapancreatic activation of trypsinogen is believed to play a critical role in the initiation of acute pancreatitis, but mechanisms responsible for intrapancreatic trypsinogen activation during pancreatitis have not been clearly defined. In previou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0246b43261781118873a75bb67274a26
https://doi.org/10.1152/ajpgi.00363.2001

Experimental acute biliary pancreatitis induced by retrograde infusion of bile acids into the mouse pancreatic duct

Autor: Johanna M. Laukkarinen, Gijs J.D. Van Acker, George Perides, Michael L. Steer

Publikováno v: Nature protocols. 5(2)

Mechanistic studies of acute pancreatitis require animal models because clinical material is generally not available during the early phases of the disease. Here we describe a protocol to induce biliary pancreatitis by retrogradely infusing bile acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9458716ab934d53ede34ba55feeef704
https://pubmed.ncbi.nlm.nih.gov/20134432

Tumor progression locus-2 is a critical regulator of pancreatic and lung inflammation during acute pancreatitis

Autor: Eric R. Weiss, Gijs J.D. Van Acker, Michael L. Steer, Philip N. Tsichlis, George Perides, Santasabuj Das

Publikováno v: The Journal of biological chemistry. 282(30)

Pancreatic and lung inflammation during acute pancreatitis is a poorly understood, but clinically important, phenomenon. The proto-oncogene Tpl2 (tumor progression locus-2) has recently been shown to have important immunomodulatory effects on some in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26135b621e104082aaeda1626c483333
https://pubmed.ncbi.nlm.nih.gov/17537724

Phosphatidylinositol 3-kinase-dependent activation of trypsinogen modulates the severity of acute pancreatitis

Autor: Ashok K. Saluja, Stephen P. Soltoff, Lakshmi Bhagat, Gijs J.D. Van Acker, Lewis C. Cantley, Albert M. Song, Vijay P. Singh, Michael L. Steer

Publikováno v: The Journal of clinical investigation. 108(9)

Intra-acinar cell activation of digestive enzyme zymogens including trypsinogen is generally believed to be an early and critical event in acute pancreatitis. We have found that the phosphatidylinositol 3-kinase inhibitor wortmannin can reduce the in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283c1e9084569ff4b18839f45c2389a7
https://pubmed.ncbi.nlm.nih.gov/11696567