Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Gihan I. Tennekoon"'
Autor:
Alison M Barnard, Rebecca J Willcocks, Erika L Finanger, Michael J Daniels, William T Triplett, William D Rooney, Donovan J Lott, Sean C Forbes, Dah-Jyuu Wang, Claudia R Senesac, Ann T Harrington, Richard S Finkel, Barry S Russman, Barry J Byrne, Gihan I Tennekoon, Glenn A Walter, H Lee Sweeney, Krista Vandenborne
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194283 (2018)
OBJECTIVE:To provide evidence for quantitative magnetic resonance (qMR) biomarkers in Duchenne muscular dystrophy by investigating the relationship between qMR measures of lower extremity muscle pathology and functional endpoints in a large ambulator
Externí odkaz:
https://doaj.org/article/e8dfd05ea09445269c042c5cef248456
Autor:
Kavya S. Nair, Donovan J. Lott, Sean C. Forbes, Alison M. Barnard, Rebecca J. Willcocks, Claudia R. Senesac, Michael J. Daniels, Ann T. Harrington, Gihan I. Tennekoon, Kirsten Zilke, Erika L. Finanger, Richard S. Finkel, William D. Rooney, Glenn A. Walter, Krista Vandenborne
Publikováno v:
J Neuromuscul Dis
Background: Muscles of boys with Duchenne muscular dystrophy (DMD) are progressively replaced by fatty fibrous tissues, and weakness leads to loss of ambulation (LoA). Step activity (SA) monitoring is a quantitative measure of real-world ambulatory f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23bf53acba5f02477e41717786060e87
https://europepmc.org/articles/PMC9257666/
https://europepmc.org/articles/PMC9257666/
Autor:
Rebecca J. Willcocks, Alison M. Barnard, Ryan J. Wortman, Claudia R. Senesac, Donovan J. Lott, Ann T. Harrington, Kirsten L. Zilke, Sean C. Forbes, William D. Rooney, Dah-Jyuu Wang, Erika L. Finanger, Gihan I. Tennekoon, Michael J. Daniels, William T. Triplett, Glenn A. Walter, Krista Vandenborne
Publikováno v:
J Neuromuscul Dis
Background: Joint contractures are common in boys and men with Duchenne muscular dystrophy (DMD), and management of contractures is an important part of care. The optimal methods to prevent and treat contractures are controversial, and the natural hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6e8403247af5ae280303c8b5186f09
https://europepmc.org/articles/PMC9257436/
https://europepmc.org/articles/PMC9257436/
Autor:
Sean C Forbes, Rebecca J Willcocks, William T Triplett, William D Rooney, Donovan J Lott, Dah-Jyuu Wang, Jim Pollaro, Claudia R Senesac, Michael J Daniels, Richard S Finkel, Barry S Russman, Barry J Byrne, Erika L Finanger, Gihan I Tennekoon, Glenn A Walter, H Lee Sweeney, Krista Vandenborne
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106435 (2014)
IntroductionDuchenne muscular dystrophy (DMD) is an X-linked recessive disorder that results in functional deficits. However, these functional declines are often not able to be quantified in clinical trials for DMD until after age 7. In this study, w
Externí odkaz:
https://doaj.org/article/b1ddd295609e4a84bb30590f29b6277c
Autor:
Rebecca J, Willcocks, William D, Rooney, William T, Triplett, Sean C, Forbes, Donovan J, Lott, Claudia R, Senesac, Michael J, Daniels, Dah-Jyuu, Wang, Ann T, Harrington, Gihan I, Tennekoon, Barry S, Russman, Erika L, Finanger, Barry J, Byrne, Richard S, Finkel, Glenn A, Walter, H Lee, Sweeney, Krista, Vandenborne
Publikováno v:
Annals of neurology. 79(4)
The aim of this study was to describe Duchenne muscular dystrophy (DMD) disease progression in the lower extremity muscles over 12 months using quantitative magnetic resonance (MR) biomarkers, collected across three sites in a large cohort.A total of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34f6092ede7b25be7715233285c2911f
https://pubmed.ncbi.nlm.nih.gov/26891991
https://pubmed.ncbi.nlm.nih.gov/26891991
Autor:
Jacqueline, Montes, Allan M, Glanzman, Elena S, Mazzone, William B, Martens, Sally, Dunaway, Amy, Pasternak, Susan O, Riley, Janet, Quigley, Shree, Pandya, Darryl C, De Vivo, Petra, Kaufmann, Claudia A, Chiriboga, Richard S, Finkel, Gihan I, Tennekoon, Basil T, Darras, Marika, Pane, Eugenio, Mercuri, Michael P, Mcdermott
Publikováno v:
Musclenerve. 52(6)
With clinical trials underway, our objective was to construct a composite score of global function that could discriminate among people with spinal muscular atrophy (SMA).Data were collected from 126 participants with SMA types 2 and 3. Scores from t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b2916db66c0fbc1e37e3316e7807be6
https://pubmed.ncbi.nlm.nih.gov/25846132
https://pubmed.ncbi.nlm.nih.gov/25846132
Autor:
Douglas Yee, Gihan I. Tennekoon, Patrick Delafontaine, Ann Randolph, Eva L. Feldman, Hsin Lin Cheng
Publikováno v:
Scopus-Elsevier
The insulin-like growth factors (IGFs) are trophic factors whose growth-promoting actions are mediated via the IGF-I receptor and modulated by six IGF binding proteins (IGFBPs). In this study, we observed increased transcripts of both IGF-I and IGF-I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9862397e9b93c5c7ebc43f862bfdeacf
https://doi.org/10.1046/j.1471-4159.1996.66020525.x
https://doi.org/10.1046/j.1471-4159.1996.66020525.x
Publikováno v:
Molecular and Cellular Neuroscience. 6:337-348
Nerve injury alters the function of Schwann cells from quiescent, myelin forming cells to proliferating cells that facilitate nerve repair. The transcription factor, Zif268, may be involved in transmitting injury-related signals since its expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::564399f281ccedeffc93160bb8f7b8fe
https://doi.org/10.1006/mcne.1995.1026
https://doi.org/10.1006/mcne.1995.1026
Publikováno v:
Neuron. 12:627-637
Expression of myelin proteins has been shown to be altered in transgenic mice that express papovaviral large tumor (T) antigens. This paper analyzes the effect on P0 gene expression in secondary Schwann cells transfected with the SV40 T antigen gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1809218205fcf98859910c4783da1b
https://doi.org/10.1016/0896-6273(94)90218-6
https://doi.org/10.1016/0896-6273(94)90218-6
Publikováno v:
Journal of Neuroscience Research. 36:216-223
Neurofibromin, the product of the neurofibromatosis type 1 (NF1) gene, is a ∼250 kDa protein expressed predominantly in cortical neurons and oligodendrocytes in the central nervous system (CNS) and sensory neurons and Schwann cells in the periphera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56e90882960a96b2984021fefc0db5d
https://doi.org/10.1002/jnr.490360212
https://doi.org/10.1002/jnr.490360212