Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Gigi N.C. Chiu"'
Autor:
William Hwang, Zhiyong Poon, Qixing Zhong, Shang Li, Sudipto Bari, Christina L. L. Chai, Alvin Soon Tiong Lim, Niraja Dighe, Tse Hui Lim, Xiubo Fan, Gigi N.C. Chiu
Publikováno v:
Stem Cells Translational Medicine. 7:376-393
Umbilical cord blood (UCB) transplants in adults have slower hematopoietic recovery compared to bone marrow (BM) or peripheral blood (PB) stem cells mainly due to low number of total nucleated cells and hematopoietic stem and progenitor cells (HSPC).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5aca744be29531b25c13548fa63416e
https://doi.org/10.1002/sctm.17-0251
https://doi.org/10.1002/sctm.17-0251
Autor:
Gigi N.C. Chiu, Yanjun Hong, Gopalakrishnan Venkatesan, Eric Chun Yong Chan, Pipin Kojodjojo, Yuanjie Liu, Eleanor Jing Yi Cheong, Janice Jia Ni Goh
Publikováno v:
Drug Metabolism and Disposition. 45:260-268
Rivaroxaban, a direct Factor Xa inhibitor, is indicated for stroke prevention in nonvalvular atrial fibrillation (AF). Studies have revealed that the clearance of rivaroxaban is largely attributed to CYP3A4, CYP2J2 metabolism, and P-glycoprotein (P-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f262cd9661ec675eb667f2d1bbb80b
https://doi.org/10.1124/dmd.116.073890
https://doi.org/10.1124/dmd.116.073890
Autor:
Edward Kai-Hua Chow, Dean Ho, Gigi N.C. Chiu, Kian Ping Loh, Giorgia Pastorin, David Tai Leong
Publikováno v:
Advanced materials (Deerfield Beach, Fla.). 30(47)
Nanomaterials have the potential to improve how patients are clinically treated and diagnosed. While there are a number of nanomaterials that can be used toward improved drug delivery and imaging, how these nanomaterials confer an advantage over othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d325706bf5e11765b113f5ec95e425f
https://pubmed.ncbi.nlm.nih.gov/30133035
https://pubmed.ncbi.nlm.nih.gov/30133035
Publikováno v:
Journal of Fluorine Chemistry. 175:68-72
New fluorinated 7-benzylamino-2-phenyl-1,2,4-triazolo[1,5- a ][1,3,5]triazin-5-amines were designed as potential anticancer agents and a practical method for their preparation was developed. The reaction of benzhydrazide with cyanoguanidine followed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc639dcfe573ecde5eb3f773380e1524
https://doi.org/10.1016/j.jfluchem.2015.03.010
https://doi.org/10.1016/j.jfluchem.2015.03.010
Publikováno v:
Nanomedicine. 9:1665-1679
Aim: The aim of this work was to develop a liposomal formulation to facilitate delivery of a synergistic safingol/C2-ceramide combination in the treatment of acute myeloid leukemia (AML). Materials & methods: Liposomes were prepared using the extrusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3656fe48c3aabb6af2b01707f47be451
https://doi.org/10.2217/nnm.13.123
https://doi.org/10.2217/nnm.13.123
Autor:
Anumita Chaudhury, Gigi N.C. Chiu, Kuan-Boone Tan, Bernice M.J. Tan, Ishaque M. Shaikh, Yuanjie Liu, Bee Jen Tan
Publikováno v:
Journal of Controlled Release. 172:852-861
Liposome co-encapsulation of synergistic anti-cancer drug combination is an emerging area that has demonstrated therapeutic benefit in clinical trials. Remote loading of two or more drugs into a single liposome constitutes a new challenge that calls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27fdb8492983aeac97fae2b3bb233f0d
https://doi.org/10.1016/j.jconrel.2013.10.025
https://doi.org/10.1016/j.jconrel.2013.10.025
Autor:
Pat Pak Yan Chu, William Hwang, Andrea Lim, Ralph M. Bunte, Gigi N.C. Chiu, Shang Li, Tony Kiat Hon Lim, Xiubo Fan, Sudipto Bari
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 9:1304-1316
In this study, carboxylic acid functionalized single walled carbon nanotubes (f-SWCNT-COOH) was shown to support the viability and ex vivo expansion of freeze-thawed, non-enriched hematopoietic stem and progenitor cells (HSPC) in human umbilical cord
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a90168a065c7768e8bfb2c71138ecf4
https://doi.org/10.1016/j.nano.2013.05.009
https://doi.org/10.1016/j.nano.2013.05.009
Publikováno v:
European Journal of Medicinal Chemistry. 67:325-334
Thirty-three 1,2,4-triazolo[1,5-a][1,3,5]triazin-5,7-dione and its 5-thioxo analogues were designed and synthesized which contained different substituents at meta- and/or para-positions of 2-phenyl or 2-benzyl ring attached to the fused ring structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb786a7fc98ee183722e52b8dcdd3097
https://doi.org/10.1016/j.ejmech.2013.06.051
https://doi.org/10.1016/j.ejmech.2013.06.051
Autor:
Ming-Ren Toh, Gigi N.C. Chiu
Publikováno v:
Asian Journal of Pharmaceutical Sciences. 8:88-95
Liposomes have been widely researched as a delivery system and there have been many manufacturing techniques used in the production of liposomal preparations, the most common being extrusion method which will be introduced in this paper. However beca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d6ad9d6f77e7ba670cd0d1dd97fc00
https://doi.org/10.1016/j.ajps.2013.07.011
https://doi.org/10.1016/j.ajps.2013.07.011
Autor:
Bee Jen Tan, Gigi N.C. Chiu
Publikováno v:
International Journal of Oncology. 42:1605-1612
Since its isolation from Tripterygium wilfordii in 1972, triptolide has been shown to possess potent anticancer activity against a variety of cancers, and has entered phase I clinical trial. It is a diterpenoid triepoxide that acts through multiple m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb70bfb7ade816c37fbb5d714c5df0ee
https://doi.org/10.3892/ijo.2013.1843
https://doi.org/10.3892/ijo.2013.1843