Zobrazeno 1 - 10
of 309
pro vyhledávání: '"Giegerich Robert"'
Autor:
Beckstette Michael, Mailänder Jens T., Marhöfer Richard J., Sczyrba Alexander, Ohlebusch Enno, Giegerich Robert, Selzer Paul M.
Publikováno v:
Journal of Integrative Bioinformatics, Vol 1, Iss 1, Pp 90-107 (2004)
With rising numbers of fully sequenced genomes the importance of comparative genomics is constantly increasing. Although several software systems for genome comparison analyses do exist, their functionality and flexibility is still limited, compared
Externí odkaz:
https://doaj.org/article/dd12fd31fd7d4f8c8ba8fb805d5ec6ad
Publikováno v:
BMC Bioinformatics, Vol 12, Iss 1, p 429 (2011)
Abstract Background Many bioinformatics tools for RNA secondary structure analysis are based on a thermodynamic model of RNA folding. They predict a single, "optimal" structure by free energy minimization, they enumerate near-optimal structures, they
Externí odkaz:
https://doaj.org/article/4b5ed28ca55a4a5f895358b13153c602
Publikováno v:
BMC Evolutionary Biology, Vol 10, Iss 1, p 167 (2010)
Abstract Background Minisatellites are genomic loci composed of tandem arrays of short repetitive DNA segments. A minisatellite map is a sequence of symbols that represents the tandem repeat array such that the set of symbols is in one-to-one corresp
Externí odkaz:
https://doaj.org/article/149e4dab76ee4767bdb092f128f4fefb
Publikováno v:
BMC Bioinformatics, Vol 11, Iss 1, p 222 (2010)
Abstract Background A widely used method to find conserved secondary structure in RNA is to first construct a multiple sequence alignment, and then fold the alignment, optimizing a score based on thermodynamics and covariance. This method works best
Externí odkaz:
https://doaj.org/article/0110128e45534532bad8e96256d7d62d
Autor:
Jänicke Sebastian, Janssen Stefan, Evguenieva-Hackenberg Elena, Daschkey Svenja, Reinkensmeier Jan, Schlüter Jan-Philip, Becker Jörg D, Giegerich Robert, Becker Anke
Publikováno v:
BMC Genomics, Vol 11, Iss 1, p 245 (2010)
Abstract Background Small untranslated RNAs (sRNAs) are widespread regulators of gene expression in bacteria. This study reports on a comprehensive screen for sRNAs in the symbiotic nitrogen-fixing alpha-proteobacterium Sinorhizobium meliloti applyin
Externí odkaz:
https://doaj.org/article/d23111132f4f4f86975ce2286074b350
Publikováno v:
BMC Bioinformatics, Vol 9, Iss 1, p 167 (2008)
Abstract Background Analysis of sequence composition is a routine task in genome research. Organisms are characterized by their base composition, dinucleotide relative abundance, codon usage, and so on. Unique subsequences are markers of special inte
Externí odkaz:
https://doaj.org/article/748a1402d3514f2d94fd09ceb0a3c6dc
Publikováno v:
BMC Bioinformatics, Vol 9, Iss 1, p 131 (2008)
Abstract Background Most non-coding RNA families exert their function by means of a conserved, common secondary structure. The Rfam data base contains more than five hundred structurally annotated RNA families. Unfortunately, searching for new family
Externí odkaz:
https://doaj.org/article/8b52df046775401e9a86976f65ff20ab
Autor:
Mersch Henning, Löwenthal Kai, Schwarzer Knut, Hartmeier Sven, Krüger Jan, Seibel Philipp N, Dandekar Thomas, Giegerich Robert
Publikováno v:
BMC Bioinformatics, Vol 7, Iss 1, p 490 (2006)
Abstract Background Today, there is a growing need in bioinformatics to combine available software tools into chains, thus building complex applications from existing single-task tools. To create such workflows, the tools involved have to be able to
Externí odkaz:
https://doaj.org/article/66eeee99ef5a4777a2c30aa019456e34
Publikováno v:
BMC Bioinformatics, Vol 7, Iss 1, p 389 (2006)
Abstract Background In biological sequence analysis, position specific scoring matrices (PSSMs) are widely used to represent sequence motifs in nucleotide as well as amino acid sequences. Searching with PSSMs in complete genomes or large sequence dat
Externí odkaz:
https://doaj.org/article/0f432faca4d44e1cb5125c7e5f3cc393
Autor:
Giegerich Robert, Steffen Peter
Publikováno v:
BMC Bioinformatics, Vol 7, Iss 1, p 214 (2006)
Externí odkaz:
https://doaj.org/article/b7d135ed8fc54b29ba46619f09c4d0fd