Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Gideon Dreyfuss"'
Autor:
Jung-Min Oh, Christopher C. Venters, Chao Di, Anna Maria Pinto, Lili Wan, Ihab Younis, Zhiqiang Cai, Chie Arai, Byung Ran So, Jingqi Duan, Gideon Dreyfuss
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
U1 snRNP is a key regulator of mRNA biogenesis through its roles in splicing, and transcription and 3’-end processing. Here the authors show a tumor suppressor-like function of U1 snRNP using in vitro cell migration/invasion assays and transcriptom
Externí odkaz:
https://doaj.org/article/94e6334d86c641beb8ea3c082c7fc160
Autor:
Ihab Younis, Kimberly Dittmar, Wei Wang, Shawn W Foley, Michael G Berg, Karen Y Hu, Zhi Wei, Lili Wan, Gideon Dreyfuss
Publikováno v:
eLife, Vol 2 (2013)
Eukaryotes have two types of spliceosomes, comprised of either major (U1, U2, U4, U5, U6) or minor (U11, U12, U4atac, U6atac;
Externí odkaz:
https://doaj.org/article/880ce9671c444546922cf4312c02e818
Publikováno v:
Methods in enzymology. 655
Full-length transcription in the majority of protein-coding and other genes transcribed by RNA polymerase II in complex eukaryotes requires U1 snRNP (U1) to co-transcriptionally suppress transcription-terminating premature 3'-end cleavage and polyade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b22939351a56cd3b31404510035167e
https://pubmed.ncbi.nlm.nih.gov/34183128
https://pubmed.ncbi.nlm.nih.gov/34183128
Autor:
Byung Ran So, Gideon Dreyfuss
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 84:239-242
This summary of the 84th Cold Spring Harbor Laboratory (CSHL) Symposium on Quantitative Biology: RNA Control and Regulation, held in May 2019, highlights key emerging themes in this field, which now impacts nearly every aspect of biology and medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cde295c34a7a3f3ff7a2929fd8e75a5
https://doi.org/10.1101/sqb.2019.84.040469
https://doi.org/10.1101/sqb.2019.84.040469
Publikováno v:
Methods in Enzymology ISBN: 9780128235737
Full-length transcription in the majority of protein-coding and other genes transcribed by RNA polymerase II in complex eukaryotes requires U1 snRNP (U1) to co-transcriptionally suppress transcription-terminating premature 3′-end cleavage and polya
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29a1b3b447dc6cb2dec7bc60d6db2518
https://doi.org/10.1016/bs.mie.2021.04.017
https://doi.org/10.1016/bs.mie.2021.04.017
Autor:
Anna Maria Pinto, Lili Wan, Chie Arai, Ihab Younis, Jiannan Guo, Christopher C. Venters, Chao Di, Zhenxi Zhang, Byung Ran So, Jung-Min Oh, Gideon Dreyfuss
Publikováno v:
Nature Structural & Molecular Biology. 24:993-999
Genome-wide analyses of the effects of U1 snRNP inhibition in human cells shows that telescripting suppresses premature cleavage and polyadenylation in long introns to sustain expression of large genes important for cell cycle and development. U1 snR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9c6ca6254db8e94525eff57b160f8d
https://doi.org/10.1038/nsmb.3473
https://doi.org/10.1038/nsmb.3473
Autor:
Gideon Dreyfuss, Zhiqiang Cai, Anna Maria Pinto, Lili Wan, Chie Arai, Ihab Younis, Jung-Min Oh, Christopher C. Venters, Byung Ran So, Chao Di
Stimulated cells and cancer cells have widespread shortening of mRNA 3’-utranslated regions (3’UTRs) and switches to shorter mRNA isoforms due to usage of more proximal polyadenylation signals (PASs) in the last exon and in introns. U1 snRNA (U1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5091944a4b3b80cf228b00f06ac1f0f
https://doi.org/10.1101/730515
https://doi.org/10.1101/730515
Autor:
Zhiqiang Cai, Chao Di, Lili Wan, Anna Maria Pinto, Byung Ran So, Jingqi Duan, Jung-Min Oh, Gideon Dreyfuss, Ihab Younis, Christopher C. Venters, Chie Arai
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Stimulated cells and cancer cells have widespread shortening of mRNA 3’-untranslated regions (3’UTRs) and switches to shorter mRNA isoforms due to usage of more proximal polyadenylation signals (PASs) in introns and last exons. U1 snRNP (U1), ver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a950e6fffda6fa87969e90c8eda6d07
https://pubmed.ncbi.nlm.nih.gov/31911652
https://pubmed.ncbi.nlm.nih.gov/31911652
Autor:
Byung Ran So, Chie Arai, Zhiqiang Cai, Chao Di, Jiannan Guo, Christopher C. Venters, Jung-Min Oh, Gideon Dreyfuss
Publikováno v:
Mol Cell
Summary Full-length transcription in the majority of human genes depends on U1 snRNP (U1) to co-transcriptionally suppress transcription-terminating premature 3′ end cleavage and polyadenylation (PCPA) from cryptic polyadenylation signals (PASs) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0027112fd4f527119667f6b80e90cafd
https://pubmed.ncbi.nlm.nih.gov/31522989
https://pubmed.ncbi.nlm.nih.gov/31522989
Autor:
Gideon Dreyfuss, Lili Wan
Publikováno v:
Cell. 170(1)
Spinal muscular atrophy (SMA) is caused by deficiency of SMN protein, which is crucial for spliceosome subunits biogenesis. Most SMA patients have SMN1 deletions, leaving SMN2 as sole SMN source; however, a C→T substitution converts an exonic-splic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33aeb2a4f72193ed4670f863c6360f06
https://pubmed.ncbi.nlm.nih.gov/28666123
https://pubmed.ncbi.nlm.nih.gov/28666123