Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gideon Davies"'
Autor:
Gareth Doherty, Geraldine Ler, Norbert Wimmer, Paul Bernhardt, Roger Ashmus, David Vocadlo, Zach Armstrong, Gideon Davies, Marco Maccarana, Jin-ping Li, Yasmin Kayal, Vito Ferro
1-Azasugar analogues of L-iduronic acid (L-IdoA) and D-glucuronic acid (D-GlcA) and their corresponding enantiomers were synthesized as potential pharmacological chaperones for mucopolysaccharidosis I (MPS I), a lysosomal storage disease caused by mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f8d2cea5f9946bea690320ad846cc74
https://doi.org/10.26434/chemrxiv-2022-dhq8q
https://doi.org/10.26434/chemrxiv-2022-dhq8q
Autor:
Jingming Zhao, Ying Zhuo, Daniel Diaz, Muralidharan Shanmugam, Abbey Telfer, Peter Lindley, Daniel Kracher, Takahiro Hayashi, Lisa Seibt, Florence Hardy, Oliver Manners, Tobias Hendison, Katherine Hollywood, Sofia Diaz-Moreno, Nigel Scrutton, Morten Tovborg, Gideon Davies, Paul Walton, Derren Heyes, Anthony Green
Oxygenase enzymes generate reactive intermediates at their active sites to effect controlled functionalizations of inert C–H bonds in substrates, such as in the enzymatic conversion of methane to methanol. To be viable catalysts, however, these enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f0283a9a945ad6f5da266485dfe2c6a
https://doi.org/10.21203/rs.3.rs-1350705/v1
https://doi.org/10.21203/rs.3.rs-1350705/v1
Publikováno v:
Chemistry – A European Journal. 28
Pixatimod (PG545), a heparan sulfate (HS) mimetic and anticancer agent currently in clinical trials, is a potent inhibitor of heparanase. Heparanase is an endo-β-glucuronidase that degrades HS in the extracellular matrix and basement membranes and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630616a4b99c63468955b6a6a24c4a8b
https://doi.org/10.1002/chem.202104222
https://doi.org/10.1002/chem.202104222
Autor:
Mahima Sharma, James Lingford, Marija Petricevic, Alexander Snow, Yunyang Zhang, Michael Jarva, Janice Mui, Nichollas Scott, Eleanor Saunders, Runyao Mao, Ruwan Epa, Bruna da Silva, Douglas Pires, David Ascher, Malcolm McConville, Gideon Davies, Spencer Williams, Ethan Goddard-Borger
Catabolism of sulfoquinovose (SQ, 6-deoxy-6-sulfoglucose), the ubiquitous sulfosugar produced by photosynthetic organisms, is an important component of the biogeochemical carbon and sulfur cycles. Here, we describe a new pathway for SQ degradation th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c43ab21741b2a474016a481b5ddcabc1
https://doi.org/10.26434/chemrxiv-2021-08j01-v4
https://doi.org/10.26434/chemrxiv-2021-08j01-v4
Autor:
Mahima Sharma, James Lingford, Marija Petricevic, Alexander Snow, Yunyang Zhang, Michael Jarva, Janice Mui, Nichollas Scott, Eleanor Saunders, Runyao Mao, Ruwan Epa, Bruna da Silva, Douglas Pires, David Ascher, Malcolm McConville, Gideon Davies, Spencer Williams, Ethan Goddard-Borger
Breakdown of the sulfosugar sulfoquinovose (SQ, 6-deoxy-6-sulfoglucose), produced by photosynthetic organisms, is an important component of the biogeochemical carbon and sulfur cycles. Here, we reveal a new pathway for SQ degradation involving oxidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1086c0e739ced22bdd8a9d15d2d7e698
https://doi.org/10.26434/chemrxiv-2021-08j01-v3
https://doi.org/10.26434/chemrxiv-2021-08j01-v3
Autor:
Mahima Sharma, James Lingford, Marija Petricevic, Alexander Snow, Yunyang Zhang, Michael Jarva, Janice Mui, Nichollas Scott, Eleanor Saunders, Runyao Mao, Ruwan Epa, Bruna da Silva, Douglas Pires, David Ascher, Malcolm McConville, Gideon Davies, Spencer Williams, Ethan Goddard-Borger
Breakdown of the sulfosugar sulfoquinovose (SQ, 6-deoxy-6-sulfoglucose), produced by photosynthetic organisms, is an important component of the biogeochemical carbon and sulfur cycles. Here, we reveal a new pathway for SQ degradation involving oxidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3117bf3ba8164fe077a02f6bf237802d
https://doi.org/10.26434/chemrxiv-2021-08j01
https://doi.org/10.26434/chemrxiv-2021-08j01
Publikováno v:
Biochemical Journal
Biochemical Journal, Portland Press, 1997, pp.945-949
Biochemical Journal, Portland Press, 1997, pp.945-949
The stereochemistry of the reaction catalysed by Serratia marcescens chitobiase was determined by HPLC separation of the anomers of N-acetylglucosamine produced during the hydrolysis of p-nitrophenyl N-acetyl-β-D-glucosaminide (PNP-GlcNAc). In the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59597972b809177b3974d9125856a469
https://doi.org/10.1042/bj3280945
https://doi.org/10.1042/bj3280945
Autor:
Szymon Krzywda, Mariusz Jaskólski, Maria Gdaniec, Zofia Dega-Szafran, Monika Grundwald-Wyspiańska, Mirosław Szafran, Zbigniew Dauter, Gideon Davies
Publikováno v:
Journal of Molecular Structure: THEOCHEM. 375:197-206
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffb5c77a4588c2f270d3535bd6b5732b
https://doi.org/10.1016/0166-1280(96)91077-5
https://doi.org/10.1016/0166-1280(96)91077-5