Výsledky vyhledávání - "Giddings, Ian"

Akademický článek

Influence of cell cycle on responses of MCF-7 cells to benzo[a]pyrene

Autor: Giddings Ian, Arlt Volker M, Hamouchene Hamza, Phillips David H

Publikováno v: BMC Genomics, Vol 12, Iss 1, p 333 (2011)

Abstract Background Benzo[a]pyrene (BaP) is a widespread environmental genotoxic carcinogen that damages DNA by forming adducts. This damage along with activation of the aryl hydrocarbon receptor (AHR) induces complex transcriptional responses in cel

Externí odkaz: https://doaj.org/article/143ebea1cb4c4990b8eb7a0a7b1fb9f3

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Akademický článek

Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2

Autor: Giddings Ian, Brewer Daniel, Arlt Volker M, Hockley Sarah L, Phillips David H

Publikováno v: BMC Genomics, Vol 7, Iss 1, p 260 (2006)

Abstract Background The multi-step process of carcinogenesis can be more fully understood by characterizing gene expression changes induced in cells by carcinogens. In this study, expression microarrays were used to monitor the activity of 18,224 cDN

Externí odkaz: https://doaj.org/article/4b1698394f0e45929c6957e9b5fa46ce

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Akademický článek

Genomic Differentiation of Neanderthals and Anatomically Modern Man Allows a Fossil–DNA-Based Classification of Morphologically Indistinguishable Hominid Bones

Autor: Scholz, Michael, Bachmann, Lutz, Nicholson, Graeme J., Bachmann, Jutta, Giddings, Ian, Rüschoff-Thale, Barbara, Czarnetzki, Alfred, Pusch, Carsten M.

Publikováno v: In The American Journal of Human Genetics 2000 66(6):1927-1932

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Accurate prediction of BRCA1 and BRCA2 heterozygous genotype using expression profiling after induced DNA damage

Autor: Kote-Jarai, Zsofia, Matthews, Lucy, Osorio, Ana, Shanley, Susan, Giddings, Ian, Moreews, François, Locke, Imogen, Evans, Gareth, Eccles, Diana

Publikováno v: Clinical Cancer Research
Clinical Cancer Research, American Association for Cancer Research, 2006, Clin Cancer Res. 2006 Jul 1;12(13):3896-901
Clinical Cancer Research, 2006, Clin Cancer Res. 2006 Jul 1;12(13):3896-901

International audience; PURPOSE: In this study, the differential gene expression changes following radiation-induced DNA damage in healthy cells from BRCA1/BRCA1 mutation carriers have been compared with controls using high-density microarray technol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::340de5994dce06eaf0be6c3f600a3a32
https://hal.inria.fr/inria-00180301

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