Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Giddabasappa A"'
Autor:
Veronica Jové, Heather Wheeler, Chiachin Wilson Lee, David R. Healy, Kymberly Levine, Erik C. Ralph, Masaya Yamaguchi, Ziyue Karen Jiang, Edward Cabral, Yingrong Xu, Jeffrey Stock, Bing Yang, Anand Giddabasappa, Paula Loria, Agustin Casimiro-Garcia, Benedikt M. Kessler, Adán Pinto-Fernández, Véronique Frattini, Paul D. Wes, Feng Wang
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109593- (2024)
Summary: Precise regulation of Type I interferon signaling is crucial for combating infection and cancer while avoiding autoimmunity. Type I interferon signaling is negatively regulated by USP18. USP18 cleaves ISG15, an interferon-induced ubiquitin-l
Externí odkaz:
https://doaj.org/article/9891ba2dcc8a4ca097d1e8e73e654873
Autor:
Jové, Veronica, Wheeler, Heather, Lee, Chiachin Wilson, Healy, David R., Levine, Kymberly, Ralph, Erik C., Yamaguchi, Masaya, Jiang, Ziyue Karen, Cabral, Edward, Xu, Yingrong, Stock, Jeffrey, Yang, Bing, Giddabasappa, Anand, Loria, Paula, Casimiro-Garcia, Agustin, Kessler, Benedikt M., Pinto-Fernández, Adán, Frattini, Véronique, Wes, Paul D., Wang, Feng
Publikováno v:
In iScience 19 April 2024 27(4)
Autor:
Montgomery, Mary Katherine, Duan, Chong, Manzuk, Lisa, Chang, Stephanie, Cubias, Aiyana, Brun, Sonja, Giddabasappa, Anand, Jiang, Ziyue Karen
Publikováno v:
In Translational Oncology February 2024 40
Autor:
Mary Katherine Montgomery, Chong Duan, Lisa Manzuk, Stephanie Chang, Aiyana Cubias, Sonja Brun, Anand Giddabasappa, Ziyue Karen Jiang
Publikováno v:
Translational Oncology, Vol 40, Iss , Pp 101833- (2024)
Lung cancer remains a leading cause of cancer-related death, but scientists have made great strides in developing new treatments recently, partly owing to the use of genetically engineered mouse models (GEMMs). GEMM tumors represent a translational m
Externí odkaz:
https://doaj.org/article/1f6dec55d9d74c09a1a45c10f6dcee86
Autor:
Feng Wang, Bing Yang, Benedikt M Kessler, Veronica Jove, Heather Wheeler, Chiachin Wilson Lee, David R Healy, Kymberly Levine, Erik C Ralph, Anand Giddabasappa, Paula Loria, Masaya Yamaguchi, Agustin Casimiro-Garcia, Adan Pinto-Fernandez, Veronique Frattini, Paul Wes
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/f788494f35044f218c66952866b4b29d
Autor:
Rakhilin, Nikolai, Yang, Bing, Spilker, Mary E., Manzuk, Lisa K., Montgomery, Mary Katherine, Shin, Eyoung, Prashad, Nadira, Hwang, Jungyeon, Song, Youngho, Loganzo, Frank, Giddabasappa, Anand, Ram, Sripad
Publikováno v:
In Journal of Controlled Release February 2023 354:244-259
Autor:
Caroline B Winn, Seo-Kyoung Hwang, Jeffrey Morin, Crystal T Bluette, Balasubramanian Manickam, Ziyue K Jiang, Anand Giddabasappa, Chang-Ning Liu, Kristin Matthews
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257694 (2021)
In oncology research, while xenograft tumor models are easily visualized and humane endpoints can be clearly defined, metastatic tumor models are often based on more subjective clinical observations as endpoints. This study aimed at identifying objec
Externí odkaz:
https://doaj.org/article/ffeb8f26e92e49e0b6b88f71e8149d0f
Autor:
Mary Katherine Montgomery, John David, Haikuo Zhang, Sripad Ram, Shibing Deng, Vidya Premkumar, Lisa Manzuk, Ziyue Karen Jiang, Anand Giddabasappa
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252950 (2021)
Unlike the majority of cancers, survival for lung cancer has not shown much improvement since the early 1970s and survival rates remain low. Genetically engineered mice tumor models are of high translational relevance as we can generate tissue specif
Externí odkaz:
https://doaj.org/article/9e68815adf6744f5993de637520b8051
Autor:
Parul Gupta, Ziyue Karen Jiang, Bing Yang, Lisa Manzuk, Edward Rosfjord, Johnny Yao, Luanna Lemon, Kavon Noorbehesht, John David, Sujiet Puthenveetil, Jeffrey M. Casavant, Elwira Muszynska, Fengping Li, Mauricio Leal, Puja Sapra, Anand Giddabasappa
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
IL13Rα2 is a cell surface tumor antigen that is overexpressed in multiple tumor types. Here, we studied biodistribution and targeting potential of an anti-IL13Rα2 antibody (Ab) and anti-tumor activity of anti-IL13Rα2-antibody-drug conjugate (ADC).
Externí odkaz:
https://doaj.org/article/81c276ef8efc4089980d81c900e94c0d
Autor:
Catherine Lee, Ziyue Karen Jiang, Simon Planken, Lisa K. Manzuk, Roberto Ortiz, Michael Hall, Kavon Noorbehesht, Sripad Ram, Timothy Affolter, Gabriel E. Troche, Nathan T. Ihle, Theodore Johnson, Youngwook Ahn, Manfred Kraus, Anand Giddabasappa
Publikováno v:
Molecular Cancer Therapeutics.
KRAS is one of the most commonly mutated oncogenes in lung, colorectal, and pancreatic cancers. Recent clinical trials directly targeting KRAS G12C presented encouraging results for a large population of non-small cell lung cancer (NSCLC), but resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b7ef6aaafa7f1fc7310d35581ada2ee
https://doi.org/10.1158/1535-7163.mct-22-0810
https://doi.org/10.1158/1535-7163.mct-22-0810