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The acquisition of clinically relevant amoxicillin resistance in Streptococcus pneumoniae requires ordered horizontal gene transfer of four loci.

Autor: Gibson, Paddy S.¹ (AUTHOR), Bexkens, Evan¹ (AUTHOR), Zuber, Sylvia¹ (AUTHOR), Cowley, Lauren A.² (AUTHOR), Veening, Jan-Willem¹ (AUTHOR) Jan-Willem.Veening@unil.ch

Publikováno v: PLoS Pathogens. 7/25/2022, Vol. 18 Issue 7, p1-31. 31p.

An efficient in vivo -inducible CRISPR interference system for group A Streptococcus genetic analysis and pathogenesis studies.

Autor: Bjånes E; Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Stream A; Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Janssen AB; Department of Fundamental Microbiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland., Gibson PS; Department of Fundamental Microbiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland., Bravo AM; Department of Fundamental Microbiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland., Dahesh S; Department of Pediatrics, University of California San Diego, La Jolla, California, USA., Baker JL; Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA.; Genomic Medicine Group, J. Craig Venter Institute, La Jolla, California, USA., Varble A; School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, New York, USA., Nizet V; Department of Pediatrics, University of California San Diego, La Jolla, California, USA.; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA., Veening J-W; Department of Pediatrics, University of California San Diego, La Jolla, California, USA.; Department of Fundamental Microbiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.

Publikováno v: MBio [mBio] 2024 Aug 14; Vol. 15 (8), pp. e0084024. Date of Electronic Publication: 2024 Jul 02.