Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Giao Q. Phan"'
Autor:
Jessica C Hassel, James Larkin, Madan Jagasia, Harriet Kluger, Omid Hamid, Jeffrey Weber, Jason Chesney, Amod Sarnaik, John M Kirkwood, Eric Whitman, Martin Wermke, Evidio Domingo-Musibay, Theresa Medina, Sajeve Thomas, Wen Shi, Karl D Lewis, Nikhil I Khushalani, Parameswaran Hari, Marlana Orloff, Mike Cusnir, Giao Q Phan, Andrew J S Furness, Michael E Egger, Friedrich Graf Finckenstein, Giri Sulur
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
Background Patients with advanced melanoma have limited treatment options after progression on immune checkpoint inhibitors (ICI). Lifileucel, a one-time autologous tumor-infiltrating lymphocyte (TIL) cell therapy, demonstrated an investigator-assess
Externí odkaz:
https://doaj.org/article/900e2415861b4b7ead600bdf8b2b9e19
Autor:
Sapna P. Patel, Megan Othus, Yuanbin Chen, G. Paul Wright, Kathleen J. Yost, John R. Hyngstrom, Siwen Hu-Lieskovan, Christopher D. Lao, Leslie A. Fecher, Thach-Giao Truong, Jennifer L. Eisenstein, Sunandana Chandra, Jeffrey A. Sosman, Kari L. Kendra, Richard C. Wu, Craig E. Devoe, Gary B. Deutsch, Aparna Hegde, Maya Khalil, Ankit Mangla, Amy M. Reese, Merrick I. Ross, Andrew S. Poklepovic, Giao Q. Phan, Adedayo A. Onitilo, Demet G. Yasar, Benjamin C. Powers, Gary C. Doolittle, Gino K. In, Niels Kokot, Geoffrey T. Gibney, Michael B. Atkins, Montaser Shaheen, James A. Warneke, Alexandra Ikeguchi, Jose E. Najera, Bartosz Chmielowski, Joseph G. Crompton, Justin D. Floyd, Eddy Hsueh, Kim A. Margolin, Warren A. Chow, Kenneth F. Grossmann, Eliana Dietrich, Victor G. Prieto, Michael C. Lowe, Elizabeth I. Buchbinder, John M. Kirkwood, Larissa Korde, James Moon, Elad Sharon, Vernon K. Sondak, Antoni Ribas
Publikováno v:
New England Journal of Medicine. 388:813-823
Autor:
Steven A. Rosenberg, James C. Yang, Nicholas P. Restifo, Sid P. Kerkar, Mary Ann Toomey, Steven A. Feldman, Udai S. Kammula, Marybeth S. Hughes, Giao Q. Phan, Richard M. Sherry, Lien T. Ngo, Azam V. Nahvi, Sadik H. Kassim, Mark E. Dudley, Zhili Zheng, Joal D. Beane, Richard A. Morgan, Ling Zhang
Supplemental figure 2. Phenotype of NFAT.IL12 gene modified TIL compared to matched untransduced TIL.Shown are the percentage of cells with a phenotype consistent with effector memory (CD62L-CD45RA-),central memory (CD62L+CD45RA-), Naive (CD62+, CD45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b62ad53dd29f0fe028259344ccc6ef
https://doi.org/10.1158/1078-0432.22457129.v1
https://doi.org/10.1158/1078-0432.22457129.v1
Autor:
Steven A. Rosenberg, James C. Yang, Nicholas P. Restifo, Sid P. Kerkar, Mary Ann Toomey, Steven A. Feldman, Udai S. Kammula, Marybeth S. Hughes, Giao Q. Phan, Richard M. Sherry, Lien T. Ngo, Azam V. Nahvi, Sadik H. Kassim, Mark E. Dudley, Zhili Zheng, Joal D. Beane, Richard A. Morgan, Ling Zhang
Supplemental figure 4. IL6 and IL10 levels. Shown are data from five patients with elevated IL12 and IFNg levels that were subject to cytokine multiplex analysis. Only cytokine IL6 and IL10 were shown to be consistently elevated post-infusion.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e695baf815b4bc7224d3617847ff746
https://doi.org/10.1158/1078-0432.22457123.v1
https://doi.org/10.1158/1078-0432.22457123.v1
Autor:
Giao Q. Phan, Steven A. Rosenberg, Catherine L. Levy, Donald E. White, Udai S. Kammula, Marybeth S. Hughes, Richard M. Sherry, James C. Yang, Peter A. Prieto
Purpose: Treatment with ipilimumab can cause objective tumor responses in patients with metastatic melanoma. We have treated 177 evaluable patients in three clinical trials and have long-term follow-up to evaluate the durability of responses.Experime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f63b891d1b0a4f6417f46020d37a79
https://doi.org/10.1158/1078-0432.c.6519870.v1
https://doi.org/10.1158/1078-0432.c.6519870.v1
Autor:
Steven A. Rosenberg, James C. Yang, Nicholas P. Restifo, Sid P. Kerkar, Mary Ann Toomey, Steven A. Feldman, Udai S. Kammula, Marybeth S. Hughes, Giao Q. Phan, Richard M. Sherry, Lien T. Ngo, Azam V. Nahvi, Sadik H. Kassim, Mark E. Dudley, Zhili Zheng, Joal D. Beane, Richard A. Morgan, Ling Zhang
supplemental figure legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d52a157271b8a79321afb83b58df0d
https://doi.org/10.1158/1078-0432.22457117
https://doi.org/10.1158/1078-0432.22457117
Autor:
Steven A. Rosenberg, Carolyn M. Laurencot, Donald E. White, Kathleen E. Morton, Daniel A. Zlott, Russell C. Langan, Jenny J. Hong, Peter A. Prieto, John R. Wunderlich, Nicholas P. Restifo, Deborah E. Citrin, Marybeth S. Hughes, Udai S. Kammula, Giao Q. Phan, James C. Yang, Richard M. Sherry, Marcos R. Garcia, Michelle M. Langhan, Colin A. Gross, Mark E. Dudley
Supplementary Figure S1; Supplementary Table S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f94fb798be3e5d1e9f601a5d4dba52
https://doi.org/10.1158/1078-0432.22442954
https://doi.org/10.1158/1078-0432.22442954
Autor:
Mark E. Dudley, Donald E. White, Seth M. Steinberg, Carolyn M. Laurencot, Kathleen E. Morton, John R. Wunderlich, Paul F. Robbins, Nicholas P. Restifo, Deborah E. Citrin, Giao Q. Phan, Marybeth S. Hughes, Udai S. Kammula, Richard M. Sherry, James C. Yang, Steven A. Rosenberg
CCR Translation for This Article from Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer Immunotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b6b475f50a620c2c70475bef1ea8b7
https://doi.org/10.1158/1078-0432.22442862
https://doi.org/10.1158/1078-0432.22442862
Autor:
Giao Q. Phan, Steven A. Rosenberg, Catherine L. Levy, Donald E. White, Udai S. Kammula, Marybeth S. Hughes, Richard M. Sherry, James C. Yang, Peter A. Prieto
CCR Translation for This Article from CTLA-4 Blockade with Ipilimumab: Long-term Follow-up of 177 Patients with Metastatic Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ade27e38a635f91415634b8a77644d
https://doi.org/10.1158/1078-0432.22443567
https://doi.org/10.1158/1078-0432.22443567
Autor:
Mark E. Dudley, Donald E. White, Seth M. Steinberg, Carolyn M. Laurencot, Kathleen E. Morton, John R. Wunderlich, Paul F. Robbins, Nicholas P. Restifo, Deborah E. Citrin, Giao Q. Phan, Marybeth S. Hughes, Udai S. Kammula, Richard M. Sherry, James C. Yang, Steven A. Rosenberg
Supplementary Figures S1-S2; Supplementary Tables S1-S2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5998d27ca7481193ba68975d894c7015
https://doi.org/10.1158/1078-0432.22442859.v1
https://doi.org/10.1158/1078-0432.22442859.v1