Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Gianpiero Spedale"'
Autor:
Jingxun Chen, Amy Tresenrider, Minghao Chia, David T McSwiggen, Gianpiero Spedale, Victoria Jorgensen, Hanna Liao, Folkert Jacobus van Werven, Elçin Ünal
Publikováno v:
eLife, Vol 6 (2017)
Differentiation programs such as meiosis depend on extensive gene regulation to mediate cellular morphogenesis. Meiosis requires transient removal of the outer kinetochore, the complex that connects microtubules to chromosomes. How the meiotic gene e
Externí odkaz:
https://doaj.org/article/7480204f0f8649d9832e1dee6c5fdc69
Autor:
Minghao Chia, Amy Tresenrider, Jingxun Chen, Gianpiero Spedale, Victoria Jorgensen, Elçin Ünal, Folkert Jacobus van Werven
Publikováno v:
eLife, Vol 6 (2017)
Cell differentiation programs require dynamic regulation of gene expression. During meiotic prophase in Saccharomyces cerevisiae, expression of the kinetochore complex subunit Ndc80 is downregulated by a 5’ extended long undecoded NDC80 transcript
Externí odkaz:
https://doaj.org/article/91cbf17886fb4fa19e5b130bec0e3358
Publikováno v:
PLoS Genetics, Vol 12, Iss 6, p e1006075 (2016)
Cell fate choices are tightly controlled by the interplay between intrinsic and extrinsic signals, and gene regulatory networks. In Saccharomyces cerevisiae, the decision to enter into gametogenesis or sporulation is dictated by mating type and nutri
Externí odkaz:
https://doaj.org/article/015d2fe0b1484affad94fb5ffde77034
Autor:
Hanna Liao, Jingxun Chen, Amy Tresenrider, Victoria Jorgensen, Gianpiero Spedale, David T. McSwiggen, Folkert J. van Werven, Minghao Chia, Elçin Ünal
Publikováno v:
eLife, Vol 6 (2017)
Differentiation programs such as meiosis depend on extensive gene regulation to mediate cellular morphogenesis. Meiosis requires transient removal of the outer kinetochore, the complex that connects microtubules to chromosomes. How the meiotic gene e
Autor:
David T. McSwiggen, Gianpiero Spedale, Minghao Chia, Amy Tresenrider, Hanna Liao, Folkert J. van Werven, Elçin Ünal, Victoria Jorgensen, Jingxun Chen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9ea6e345376d274b9784e6edd7d78e9
https://doi.org/10.7554/elife.27417.038
https://doi.org/10.7554/elife.27417.038
Publikováno v:
PLOS
PLoS Genetics, Vol 12, Iss 6, p e1006075 (2016)
PLoS Genetics
PLoS Genetics, Vol 12, Iss 6, p e1006075 (2016)
PLoS Genetics
Cell fate choices are tightly controlled by the interplay between intrinsic and extrinsic signals, and gene regulatory networks. In Saccharomyces cerevisiae, the decision to enter into gametogenesis or sporulation is dictated by mating type and nutri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dce058aee9afa47595e2ea1a64071ea
https://orcid.org/0000-0001-9837-0314
https://orcid.org/0000-0001-9837-0314
Autor:
Gianpiero Spedale, Albert J. R. Heck, W.W.M. Pim Pijnappel, Nikolai Mischerikow, H. T. Marc Timmers
Publikováno v:
The Journal of biological chemistry. 285(30)
The Saccharomyces cerevisiae Spt-Ada-Gcn5 acetyltransferase (SAGA) protein complex is a coactivator for transcription by RNA polymerase II and has various activities, including acetylation and deubuiqitination of histones and recruitment of TATA-bind
Autor:
Ying Hui Wang, Jacques Bonnet, W.W.M. Pim Pijnappel, Bruno Kieffer, Didier Devys, Ali Hamiche, Lśszló Tora, Gianpiero Spedale, Christophe Romier, H. Th. Marc Timmers, R. Andrew Atkinson
Publikováno v:
EMBO Reports
EMBO Reports, 2010, 11 (8), pp.612-618. ⟨10.1038/embor.2010.98⟩
EMBO Reports, EMBO Press, 2010, 11 (8), pp.612-618. ⟨10.1038/embor.2010.98⟩
EMBO Reports, 2010, 11 (8), pp.612-618. ⟨10.1038/embor.2010.98⟩
EMBO Reports, EMBO Press, 2010, 11 (8), pp.612-618. ⟨10.1038/embor.2010.98⟩
International audience; SAGA (Spt-Ada-Gcn5 acetyltransferase), a coactivator complex involved in chromatin remodelling, harbours both histone acetylation and deubiquitination activities. ATXN7/Sgf73 and ATXN7L3, two subunits of the SAGA deubiquitinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1232294552c41059e1432fffcfe8a8
https://doi.org/10.1038/embor.2010.98
https://doi.org/10.1038/embor.2010.98
Autor:
Gianpiero Spedale, H. Th. Marc Timmers, A. F. Maarten Altelaar, Nikolai Mischerikow, Albert J. R. Heck, W.W.M. Pim Pijnappel
Publikováno v:
Journal of proteome research. 8(11)
The basal transcription factor TFIID and the chromatin-modifying complex SAGA, which have several subunits in common, are crucial for transcription regulation. Here, we describe an in-depth profiling of post-translational modifications (PTMs) on both