Retraction Note to: Learning Impairments, Memory Deficits, and Neuropathology in Aged Tau Transgenic Mice Are Dependent on Leukotrienes Biosynthesis: Role of the cdk5 Kinase Pathway.

Autor: Giannopoulos PF; Alzheimer's Center at Temple, Lewis Katz School of Medicine, Scott Richards North Star Foundation Chair, Alzheimer's Research, Temple University, 947, Medical Education and Research Building, 3500 North Broad Street, Philadelphia, PA, 19140, USA., Chiu J; Alzheimer's Center at Temple, Lewis Katz School of Medicine, Scott Richards North Star Foundation Chair, Alzheimer's Research, Temple University, 947, Medical Education and Research Building, 3500 North Broad Street, Philadelphia, PA, 19140, USA., Praticò D; Alzheimer's Center at Temple, Lewis Katz School of Medicine, Scott Richards North Star Foundation Chair, Alzheimer's Research, Temple University, 947, Medical Education and Research Building, 3500 North Broad Street, Philadelphia, PA, 19140, USA. praticod@temple.edu.

Publikováno v: Molecular neurobiology [Mol Neurobiol] 2024 Dec; Vol. 61 (12), pp. 11026-11027.

Retraction Note to: Gene knockout of 5-lipoxygenase rescues synaptic dysfunction and improves memory in the triple-transgenic model of Alzheimer's disease.

Autor: Giannopoulos PF; Center for Translational Medicine and Temple University School of Medicine, Philadelphia, PA, USA.; Department of Pharmacology, Temple University School of Medicine, Philadelphia, PA, USA., Chu J; Center for Translational Medicine and Temple University School of Medicine, Philadelphia, PA, USA.; Department of Pharmacology, Temple University School of Medicine, Philadelphia, PA, USA., Joshi YB; Center for Translational Medicine and Temple University School of Medicine, Philadelphia, PA, USA.; Department of Pharmacology, Temple University School of Medicine, Philadelphia, PA, USA., Sperow M; Center for Substance Abuse Research, Temple University School of Medicine, Philadelphia, PA, USA., Li JG; Center for Translational Medicine and Temple University School of Medicine, Philadelphia, PA, USA.; Department of Pharmacology, Temple University School of Medicine, Philadelphia, PA, USA., Kirby LG; Center for Substance Abuse Research, Temple University School of Medicine, Philadelphia, PA, USA.; Department of Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, PA, USA., Praticò D; Center for Translational Medicine and Temple University School of Medicine, Philadelphia, PA, USA. praticod@temple.edu.; Department of Pharmacology, Temple University School of Medicine, Philadelphia, PA, USA. praticod@temple.edu.

Publikováno v: Molecular psychiatry [Mol Psychiatry] 2023 Feb; Vol. 28 (2), pp. 964.

Overexpression of 5-Lipoxygenase Worsens the Phenotype of a Mouse Model of Tauopathy.

Autor: Giannopoulos PF; Center for Translational Medicine, Department of Pharmacology, Lewis Katz School of Medicine, Temple University, 3500 North Broad Street, MERB, 947, Philadelphia, PA, 19140, USA., Praticò D; Center for Translational Medicine, Department of Pharmacology, Lewis Katz School of Medicine, Temple University, 3500 North Broad Street, MERB, 947, Philadelphia, PA, 19140, USA. praticod@temple.edu.

Publikováno v: Molecular neurobiology [Mol Neurobiol] 2018 Jul; Vol. 55 (7), pp. 5926-5936. Date of Electronic Publication: 2017 Nov 11.

Brain 5-lipoxygenase over-expression worsens memory, synaptic integrity, and tau pathology in the P301S mice.

Autor: Vagnozzi AN; Department of Pharmacology, Center for Translational Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA., Giannopoulos PF; Department of Pharmacology, Center for Translational Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA., Praticò D; Department of Pharmacology, Center for Translational Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA.

Publikováno v: Aging cell [Aging Cell] 2018 Feb; Vol. 17 (1). Date of Electronic Publication: 2017 Nov 04.

Pharmacologic inhibition of 5-lipoxygenase improves memory, rescues synaptic dysfunction, and ameliorates tau pathology in a transgenic model of tauopathy.

Autor: Giannopoulos PF; Center for Translational Medicine; Department of Pharmacology., Chu J; Center for Translational Medicine; Department of Pharmacology., Sperow M; Center for Substance Abuse Research., Li JG; Center for Translational Medicine; Department of Pharmacology., Yu WH; Taub Institute for Alzheimer's Disease Research, Department of Pathology and Cell Biology, Columbia University, New York, New York., Kirby LG; Center for Substance Abuse Research; Department of Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, Pennsylvania., Abood M; Center for Substance Abuse Research; Department of Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, Pennsylvania., Praticò D; Center for Translational Medicine; Department of Pharmacology. Electronic address: praticod@temple.edu.

Publikováno v: Biological psychiatry [Biol Psychiatry] 2015 Nov 15; Vol. 78 (10), pp. 693-701. Date of Electronic Publication: 2015 Feb 07.