Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Gianni Sacchetti"'
Autor:
Stefania Costa, Paola Tedeschi, Luca Ferraro, Sarah Beggiato, Alessandro Grandini, Stefano Manfredini, Raissa Buzzi, Gianni Sacchetti, Giuseppe Valacchi
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-14 (2022)
Abstract Cortisone is a metabolite belonging to the corticosteroid class that is used pharmaceutically directly as a drug or prodrug. In addition to its large consumption, its use is linked to several side effects, so pharmaceutical research aims to
Externí odkaz:
https://doaj.org/article/f8a7396baa60440a802cfd1eec4657ea
Autor:
Cristina Zuccato, Lucia Carmela Cosenza, Chiara Tupini, Alessia Finotti, Gianni Sacchetti, Daniele Simoni, Roberto Gambari, Ilaria Lampronti
Publikováno v:
Molecules, Vol 29, Iss 1, p 8 (2023)
Induction of fetal hemoglobin (HbF) is highly beneficial for patients carrying β-thalassemia, and novel HbF inducers are highly needed. Here, we describe a new class of promising HbF inducers characterized by an isoxazole chemical skeleton and obtai
Externí odkaz:
https://doaj.org/article/e1abf3e761f14c6eaf81ed7b2c14153a
Autor:
Paola Giorni, Giulia Bulla, Giulia Leni, Mariangela Soldano, Massimo Tacchini, Alessandra Guerrini, Gianni Sacchetti, Terenzio Bertuzzi
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
IntroductionToday, alternative strategies based on the use of bioactive compounds have been proposed to reduce mycotoxin contamination and limit the use of chemical fungicides.MethodsIn the present work, several by-products collected from the agri-fo
Externí odkaz:
https://doaj.org/article/4638db3986d74d0186f21320033380fa
Autor:
Elena Catanzaro, Eleonora Turrini, Tessa Kerre, Simon Sioen, Ans Baeyens, Alessandra Guerrini, Mohamed Lamin Abdi Bellau, Gianni Sacchetti, Guglielmo Paganetto, Dmitri V. Krysko, Carmela Fimognari
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 154, Iss , Pp 113662- (2022)
Ferroptosis induction is an emerging strategy to treat cancer and contrast the tricky issue of chemoresistance, which can arise towards apoptosis. This work elucidates the anticancer mechanisms evoked by perillaldehyde, a monoterpenoid isolated from
Externí odkaz:
https://doaj.org/article/79769f266e7c4fe381783b5016eeade1
Publikováno v:
Toxins, Vol 15, Iss 6, p 360 (2023)
Since ancient times, mushrooms have been considered valuable allies of human well-being both from a dietary and medicinal point of view. Their essential role in several traditional medicines is explained today by the discovery of the plethora of biom
Externí odkaz:
https://doaj.org/article/cfc858b681a04e04a32d9319dc65178e
Autor:
Elisabetta Melloni, Silvia Grassilli, Arianna Romani, Erika Rimondi, Annalisa Marcuzzi, Enrico Zauli, Paola Secchiero, Guglielmo Paganetto, Alessandra Guerrini, Gianni Sacchetti, Massimo Tacchini
Publikováno v:
Nutrients, Vol 15, Iss 7, p 1727 (2023)
Convolvulus pluricaulis (CP) is a common Indian herb, largely employed in Ayurvedic medicine and known for its neuroprotective and neuroinflammatory action. Its effectiveness against several pathologic/sub-pathologic conditions is widely accepted, bu
Externí odkaz:
https://doaj.org/article/ca7b2586fd794a77b96aae4c30301d29
Autor:
Alessandra Guerrini, Massimo Tacchini, Ilaria Chiocchio, Alessandro Grandini, Matteo Radice, Immacolata Maresca, Guglielmo Paganetto, Gianni Sacchetti
Publikováno v:
Antibiotics, Vol 12, Iss 1, p 177 (2023)
Essential oils (EOs) and their vapour phase of Curcuma longa (Zingiberaceae), Cymbopogon citratus (Poaceae), Ocimum campechianum (Lamiaceae), and Zingiber officinale (Zingiberaceae) of cultivated plants grown in an Amazonian Ecuador area were chemica
Externí odkaz:
https://doaj.org/article/53b75cc934324f7dbc4e5ea7abd1043d
Autor:
Chiara Tupini, Adriana Chilin, Alice Rossi, Ida De Fino, Alessandra Bragonzi, Elisabetta D’Aversa, Lucia Carmela Cosenza, Christian Vaccarin, Gianni Sacchetti, Monica Borgatti, Anna Tamanini, Maria Cristina Dechecchi, Francesca Sanvito, Roberto Gambari, Giulio Cabrini, Ilaria Lampronti
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14483 (2022)
A series of new-generation TMA (4,6,4′-trimethyl angelicin) analogues was projected and synthetized in order to ameliorate anti-inflammatory activity, with reduced or absent toxicity. Since the NF-κB transcription factor (TF) plays a critical role
Externí odkaz:
https://doaj.org/article/44a522bed2fa4ba4a4fa5511e2829d0f
Improved Trimethylangelicin Analogs for Cystic Fibrosis: Design, Synthesis and Preliminary Screening
Autor:
Christian Vaccarin, Daniela Gabbia, Erica Franceschinis, Sara De Martin, Marco Roverso, Sara Bogialli, Gianni Sacchetti, Chiara Tupini, Ilaria Lampronti, Roberto Gambari, Giulio Cabrini, Maria Cristina Dechecchi, Anna Tamanini, Giovanni Marzaro, Adriana Chilin
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11528 (2022)
A small library of new angelicin derivatives was designed and synthesized with the aim of bypassing the side effects of trimethylangelicin (TMA), a promising agent for the treatment of cystic fibrosis. To prevent photoreactions with DNA, hindered sub
Externí odkaz:
https://doaj.org/article/ac4097f0c602425aa4b1f0e52423b399
Autor:
Mohamed Lamin Abdi Bellau, Matteo Andrea Chiurato, Annalisa Maietti, Giancarlo Fantin, Paola Tedeschi, Nicola Marchetti, Massimo Tacchini, Gianni Sacchetti, Alessandra Guerrini
Publikováno v:
Molecules, Vol 27, Iss 15, p 5013 (2022)
The ethnobotany of the Sahrawi people considers various species of plants and crude drugs as food, cooking spices and traditional health remedies. From among these, the fruits of Ammodaucus leucotrichus Coss. & Dur. (Apiaceae), known as Saharan cumin
Externí odkaz:
https://doaj.org/article/c1365db6ebf54cdab2ecae38ce288e99