Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Gianni Podda"'
Autor:
Dolores Viña, Verónica García-Morales, Fernanda Borges, Gianni Podda, Lourdes Santana, Carmen Picciau, Giovanna Delogu, Elías Quezada, Francisco Orallo
Publikováno v:
Molecules, Vol 15, Iss 1, Pp 270-279 (2010)
A series of 6-halo-3-hydroxyphenylcoumarins (resveratrol-coumarins hybrid derivatives) was synthesized in good yields by a Perkin reaction followed by hydrolysis. The new compounds were evaluated for their vasorelaxant activity in intact rat aorta ri
Externí odkaz:
https://doaj.org/article/831806c517d1417bb987a5c56bc375ac
Autor:
Giovanna Delogu, Lourdes Santana, Carmen Picciau, Gianni Podda, Elias Quezada q, Maria Joao Matos, M. Benedetta Fadda, Benedetta Era, Marcella Corda, Antonella Fais
Publikováno v:
Molecules, Vol 14, Iss 7, Pp 2514-2520 (2009)
In the present work we report on the contribution of the coumarin moiety to tyrosinase inhibition. Coumarin-resveratrol hybrids 1-8 have been resynthesized to investigate the structure-activity relationships and the IC50 values of these compounds wer
Externí odkaz:
https://doaj.org/article/e1c0af23f9fd42a78d2c9b79ffdeba15
Publikováno v:
Molecules, Vol 14, Iss 3, Pp 1044-1055 (2009)
The immobilization of some coumarin derivatives on modified poly(ethylene glycol)s is reported and the influence of the polymeric support on the photoluminescence activity of the compounds is discussed. Upon ultraviolet excitation, the derivatives sh
Externí odkaz:
https://doaj.org/article/9adce99d946748508d55c1ee040cfdbd
Autor:
Gianni Podda, Carmen Picciau, Eugenio Uriarte, Dolores Viña, Giulio Ferino, Giovanna Delogu, Elias Quezada
Publikováno v:
European Journal of Medicinal Chemistry. 46:1147-1152
Monoamine oxidase (MAO) is an important drug target for the treatment of neurological disorders. Series of 3-indolyl and 3-thiophenylcoumarins were synthesized and evaluated as inhibitors of the two human MAO isoforms, hMAO-A and hMAO-B. In general,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d2b0380e63041a0b0f36f51c6f420b
https://doi.org/10.1016/j.ejmech.2011.01.033
https://doi.org/10.1016/j.ejmech.2011.01.033
Publikováno v:
Synthesis. 2010:2763-2766
Regioselective syntheses of 3-arylcoumarins possessing a bromine substituent either on the 3-aryl ring, the coumarin moiety or on a lateral chain of a coumarin is reported. The regioselectivity is influenced by the substituents present in the substra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::355d25b5ae993f438d4e6a1982a8f57e
https://doi.org/10.1055/s-0029-1218835
https://doi.org/10.1055/s-0029-1218835
Autor:
Florencio M. Ubeira, María Auxiliadora Dea-Ayuela, Humberto González-Díaz, Lazaro G. Perez-Montoto, Gianni Podda, Riccardo Concu, Eugenio Uriarte, Francisco Bolás-Fernández, Francisco J. Prado-Prado
Publikováno v:
Journal of Proteome Research. 8:4372-4382
The number of protein and peptide structures included in Protein Data Bank (PDB) and Gen Bank without functional annotation has increased. Consequently, there is a high demand for theoretical models to predict these functions. Here, we trained and va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1927e30b6bd0cb1d513c022bbfd273
https://doi.org/10.1021/pr9003163
https://doi.org/10.1021/pr9003163
Autor:
Dolores Viña, Giovanna Delogu, C Picciau, Elias Quezada, Gianni Podda, Maria João Matos, Lourdes Santana
Publikováno v:
Helvetica Chimica Acta. 92:1309-1314
Arenofurans have important biological and pharmacological activities. Compared to benzofurans, the reports on the synthesis of benzodifurans are rather limited. Here, we report the synthesis of a linear and an angular 3,3′-bis(carboxymethyl)substit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d82425f4a6822bf079cbe9cc0292f3d
https://doi.org/10.1002/hlca.200800421
https://doi.org/10.1002/hlca.200800421
Publikováno v:
Molecules
Volume 14
Issue 3
Pages 1044-1055
Molecules, Vol 14, Iss 3, Pp 1044-1055 (2009)
Volume 14
Issue 3
Pages 1044-1055
Molecules, Vol 14, Iss 3, Pp 1044-1055 (2009)
The immobilization of some coumarin derivatives on modified poly(ethylene glycol)s is reported and the influence of the polymeric support on the photoluminescence activity of the compounds is discussed. Upon ultraviolet excitation, the derivatives sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15543339a29ffae96223f0061bcab47
https://doi.org/10.3390/molecules14031044
https://doi.org/10.3390/molecules14031044
Publikováno v:
Tetrahedron. 64:6755-6759
The regioselective reaction of 2,2′-dihydroxybiphenyl with terminal alkynes was found to be rapidly catalyzed by InCl3 and ZrCl4. The chemoselectivity of catalysts and alkynes for biphenol over water, together with the reaction mechanism are discus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::169eaa182f8e9efe997904fc1d3ff458
https://doi.org/10.1016/j.tet.2008.05.011
https://doi.org/10.1016/j.tet.2008.05.011
Autor:
Humberto González-Díaz, Edrey Rodríguez, Gianni Podda, Gustavo de la Riva, Aminael Sánchez-Rodríguez, Guillermin Agüero-Chapin, Roberto I. Vazquez-Padron
Publikováno v:
Journal of Chemical Information and Modeling. 48:434-448
The study of type III RNases constitutes an important area in molecular biology. It is known that the pac1+ gene encodes a particular RNase III that shares low amino acid similarity with other genes despite having a double-stranded ribonuclease activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a42b0bd2d8f62580e248cba4d0be3c3a
https://doi.org/10.1021/ci7003225
https://doi.org/10.1021/ci7003225