Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Gianni Pinardi"'
Autor:
Gianni Pinardi, Hugo F. Miranda
Publikováno v:
Pharmacological Reports. 61:268-274
To enhance analgesia, the combinatorial use of analgesic drugs with proven efficacies is a widely-used strategy to reduce adverse side effects. The present study characterizes the antinociceptive interaction of intrathecal morphine co-administered wi
Publikováno v:
Pharmacology & Toxicology. 87:116-119
Autor:
Juan Carlos Prieto, Gianni Pinardi, Juan Espinoza, Ramiro J. Zepeda, Rodrigo L. Castillo, Jaime Zamorano, Hugo F. Miranda, Ernesto Larraín
Publikováno v:
International Journal of Pharmacology. 4:208-212
Publikováno v:
Pharmacology Biochemistry and Behavior. 88:481-486
Multiple analgesic–drug combinations are commonly used in the management of acute and chronic pain in humans during multimodal or balanced analgesia. At present, these combinations are used empirically in clinical practice and are considered to be
Publikováno v:
Brain Research. 1049:165-170
The antinociception induced by the intrathecal coadministration of combinations of morphine with the nonsteroidal anti-inflammatory drugs (NSAIDs) naproxen, piroxicam, metamizol, diclofenac and ketoprofen was studied by isobolographic analysis in the
Publikováno v:
Acta Cardiologica. 60:253-257
Objective - The effects of the co-administration of fenoldopam (FD) or levodopa (LD) with dopamine (DA) on arterial blood pressure were studied in rats to assess the possibility of synergic effects that might be of some clinical importance. Methods a
Publikováno v:
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
The inhibition of cyclooxygenase enzymes by nonsteroidal anti-inflammatory drugs (NSAIDs) does not completely explain the antinociceptive efficacy of these agents. It is known that cholinergic agonists are antinociceptive, and this study evaluates th
Publikováno v:
British Journal of Pharmacology. 135:1591-1597
The common mechanism of action of non-steroidal anti-inflammatory drugs (NSAIDs) is the inhibition of the enzyme cyclo-oxygenase (COX), however, this inhibition is not enough to completely account for the efficacy of these agents in several models of
Publikováno v:
Anesthesia & Analgesia. 93:430-435
We evaluated the noradrenergic modulation of the antinociceptive activity of diclofenac in mice using the acetic acid writhing test. Dose-response curves were obtained for the antinociceptive effect of diclofenac, phenylephrine, clonidine, desipramin
Publikováno v:
Inflammation. 25:233-239
The interaction between the antinociceptive activity of ketoprofen and adrenergic agents was evaluated in the writhing test of mice. Dose-response curves were obtained for systemic and intrathecal antinociceptive effects of ketoprofen, phenylephrine,