Zobrazeno 1 - 10
of 321
pro vyhledávání: '"Gianni Pezzoli"'
Autor:
Ioannis U. Isaias, Laura Caffi, Linda Borellini, Antonella M. Ampollini, Marco Locatelli, Gianni Pezzoli, Alberto Mazzoni, Chiara Palmisano
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Gait disturbance is a common and severe symptom of Parkinson’s disease that severely impairs quality of life. Current treatments provide only partial benefits with wide variability in outcomes. Also, deep brain stimulation of the subthalamic nucleu
Externí odkaz:
https://doaj.org/article/8619494cd6dc4ab8ba49297688cd8a82
Gait-related beta-gamma phase amplitude coupling in the subthalamic nucleus of parkinsonian patients
Autor:
AmirAli Farokhniaee, Chiara Palmisano, Jasmin Del Vecchio Del Vecchio, Gianni Pezzoli, Jens Volkmann, Ioannis U. Isaias
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Analysis of coupling between the phases and amplitudes of neural oscillations has gained increasing attention as an important mechanism for large-scale brain network dynamics. In Parkinson’s disease (PD), preliminary evidence indicates abn
Externí odkaz:
https://doaj.org/article/f880fe8ea01f48e2bce9d4f03556bad6
Autor:
Samanta Mazzetti, Federica Giampietro, Alessandra Maria Calogero, Huseyin Berkcan Isilgan, Gloria Gagliardi, Chiara Rolando, Francesca Cantele, Miriam Ascagni, Manuela Bramerio, Giorgio Giaccone, Ioannis Ugo Isaias, Gianni Pezzoli, Graziella Cappelletti
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract Highly specialized microtubules in neurons are crucial to both health and disease of the nervous system, and their properties are strictly regulated by different post-translational modifications, including α-Tubulin acetylation. An imbalanc
Externí odkaz:
https://doaj.org/article/ca64ae35c99a45449e10f133fad7079d
Autor:
Federica Avantaggiato, AmirAli Farokhniaee, Andrea Bandini, Chiara Palmisano, Ibrahem Hanafi, Gianni Pezzoli, Alberto Mazzoni, Ioannis U. Isaias
Publikováno v:
Neurobiology of Disease, Vol 185, Iss , Pp 106239- (2023)
Background: Speech impairment is commonly reported in Parkinson's disease and is not consistently improved by available therapies – including deep brain stimulation of the subthalamic nucleus (STN-DBS), which can worsen communication performance in
Externí odkaz:
https://doaj.org/article/090bff23e6364191baa0edd7c94e3694
Autor:
Nicoló Gabriele Pozzi, Francesco Bolzoni, Gabriele Eliseo Mario Biella, Gianni Pezzoli, Chi Wang Ip, Jens Volkmann, Paolo Cavallari, Esther Asan, Ioannis Ugo Isaias
Publikováno v:
Cells, Vol 12, Iss 21, p 2529 (2023)
The pathophysiology of tremor in Parkinson’s disease (PD) is evolving towards a complex alteration to monoaminergic innervation, and increasing evidence suggests a key role of the locus coeruleus noradrenergic system (LC-NA). However, the difficult
Externí odkaz:
https://doaj.org/article/e0309fcbd42841d989bb2ef1c2b9b2dc
TARDBP mutations in a cohort of Italian patients with Parkinson’s disease and atypical parkinsonisms
Autor:
Cinzia Tiloca, Stefano Goldwurm, Narghes Calcagno, Federico Verde, Silvia Peverelli, Daniela Calini, Anna Lena Zecchinelli, Davide Sangalli, Antonia Ratti, Gianni Pezzoli, Vincenzo Silani, Nicola Ticozzi
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
BackgroundAggregates of TAR DNA-binding protein of 43 kDa (TDP-43) represent the pathological hallmark of most amyotrophic lateral sclerosis (ALS) and of nearly 50% of frontotemporal dementia (FTD) cases but were also observed to occur as secondary n
Externí odkaz:
https://doaj.org/article/eb671e391cbd40588ece756b7b9d30d2
Autor:
Alessandra Maria Calogero, Milo Jarno Basellini, Huseyin Berkcan Isilgan, Francesca Longhena, Arianna Bellucci, Samanta Mazzetti, Chiara Rolando, Gianni Pezzoli, Graziella Cappelletti
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12287 (2023)
Emerging evidence supports that altered α-tubulin acetylation occurs in Parkinson’s disease (PD), a neurodegenerative disorder characterized by the deposition of α-synuclein fibrillary aggregates within Lewy bodies and nigrostriatal neuron degene
Externí odkaz:
https://doaj.org/article/2d0d541fcd644c5e97f86bd1b34bb20e
Autor:
Matteo Vissani, Chiara Palmisano, Jens Volkmann, Gianni Pezzoli, Silvestro Micera, Ioannis U. Isaias, Alberto Mazzoni
Publikováno v:
npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Excessive beta-band oscillations in the subthalamic nucleus are key neural features of Parkinson’s disease. Yet the distinctive contributions of beta low and high bands, their dependency on striatal dopamine, and their correlates with move
Externí odkaz:
https://doaj.org/article/7cdbebd38a5e41d29578bb5a2a0167c6
Autor:
Milo Jarno Basellini, Josine Marie Kothuis, Alessandro Comincini, Gianni Pezzoli, Graziella Cappelletti, Samanta Mazzetti
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 28, Iss 2, p 33 (2023)
Alpha-synuclein inclusions are the distinctive trait of brain areas affected by neurodegeneration in Parkinson’s disease (PD). Nevertheless, PD is now considered as a multisystemic disorder, since alpha-synuclein pathology has been described also o
Externí odkaz:
https://doaj.org/article/153dbac3e63d45c78ba30fb7e52a9917
Autor:
Ioannis U. Isaias, Joachim Brumberg, Nicoló G. Pozzi, Chiara Palmisano, Andrea Canessa, Giorgio Marotta, Jens Volkmann, Gianni Pezzoli
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 4, Pp 579-583 (2020)
Abstract Pathophysiological understanding of gait and balance disorders in Parkinson’s disease is insufficient and late recognition of fall risk limits efficacious follow‐up to prevent or delay falls. We show a distinctive reduction of glucose me
Externí odkaz:
https://doaj.org/article/eed45dc0d2cc4d129009b9385841e695