Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Gianni Losano"'
Autor:
Pasquale Pagliaro, Raffaella Rastaldo, Lisa Accomasso, Anna Folino, Gianni Losano, Claudia Giachino, Pier Giorgio Montarolo
Aim Apelin, the ligand of the G-protein-coupled receptor (GPCR) APJ, exerts a post-conditioning-like protection against ischaemia/reperfusion injury through activation of PI3K-Akt-NO signalling. The pathway connecting APJ to PI3K is still unknown. As
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3c4ba0b781b995044c7fc656b82aff
http://hdl.handle.net/2318/1648069
http://hdl.handle.net/2318/1648069
Autor:
Maria Elisabetta Carere, Gianni Losano, Andrea Elio Sprio, Maria Prat, Anna Folino, Mattia Berrone, Raffaella Rastaldo, Paolina Salamone, Zhiqian Yang, F Di Scipio, Giovanni Nicolao Berta
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1840:2152-2161
Background The heart is unable to regenerate its tissues after severe injuries. Stem cell therapy appears to be one of the most promising approaches, though preclinical results are hitherto contradictory and clinical trials scanty and/or limited to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd5104280d22bb1ee20aa46f3044163
https://doi.org/10.1016/j.bbagen.2014.03.005
https://doi.org/10.1016/j.bbagen.2014.03.005
Autor:
Giulia Ronchi, Gianni Losano, Stefania Raimondo, Stefano Geuna, Daniele Mancardi, Raffaella Rastaldo, Sandra Cappello, Pasquale Pagliaro, Claudia Penna
Publikováno v:
Journal of Cellular and Molecular Medicine
Little is known on the early homing features of transplanted mesenchymal stem cells (MSCs). We used the isolated rat heart model to study the homing of MSCs injected in the ventricular wall of a beating heart. In this model all types of cells and mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1346d69e3d429a80bf012e5f9d4103b9
http://europepmc.org/articles/PMC3822539
http://europepmc.org/articles/PMC3822539
Autor:
Sandra Cappello, Raffaella Rastaldo, Claudia Penna, Daniele Mancardi, Pasquale Pagliaro, Nico Westerhof, Gianni Losano
Publikováno v:
Life Sciences. 81:779-793
Nitric oxide (NO) participates in the control of contractility and heart rate, limits cardiac remodeling after an infarction and contributes to the protective effect of ischemic pre- and postconditioning. Low concentrations of NO, with production of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed1f26ffcd6d85d085f15a2cd3cb7afe
https://doi.org/10.1016/j.lfs.2007.07.019
https://doi.org/10.1016/j.lfs.2007.07.019
Autor:
Sandra Cappello, Maria Carmela Cerra, Pasquale Pagliaro, Claudia Penna, Tommaso Angelone, Gianni Losano, Angelo Corti, Bruno Tota, Raffaella Rastaldo
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 293:H719-H727
The acidic protein chromogranin A (CgA) is the precursor of several regulatory peptides generated by specific proteolytic processes. Human recombinant CgA NH2-terminal fragment STA-CgA1-78 (hrSTA-CgA1-78), containing vasostatin-1 (CgA1-76) domain, ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5849cf13e69dc44144226818c3b56be4
https://doi.org/10.1152/ajpheart.01352.2006
https://doi.org/10.1152/ajpheart.01352.2006
Publikováno v:
Cardiovascular Research. 75:168-177
Objective Postconditioning (PostC) maneuvers allow post-ischemic accumulation of autacoids, which trigger protection. We tested if PostC-triggering includes bradykinin (BK) B2 receptor activation and its downstream pathway. Methods and results Isolat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::037153d6249e2003d0dbb76b7085b015
https://doi.org/10.1016/j.cardiores.2007.03.001
https://doi.org/10.1016/j.cardiores.2007.03.001
Autor:
Francesca Bonafè, Pasquale Pagliaro, Andrea Marcantoni, Claudia Penna, Giuseppe Alloatti, Gianni Losano, Maria Pia Gallo, Renzo Levi, Roberta Ramella
Publikováno v:
Journal of Cellular Biochemistry. 100:86-99
In order to assess, in a controlled in vitro model, the differentiation potential of adult bone marrow derived stem cells we have developed a coculture procedure using adult rat cardiomyocytes and mesenchymal stem cells (MSCs) from transgenic GFP pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f9af791c6ad2e0bbc5e511f315c45d
https://doi.org/10.1002/jcb.21012
https://doi.org/10.1002/jcb.21012
Autor:
Sandra Cappello, Giovanni Nicolao Berta, Giuseppe Alloatti, Donatella Gattullo, Claudia Penna, Pasquale Pagliaro, Gianni Losano, Barbara Mognetti
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 288:H2512-H2520
Ischemic preconditioning (IP) is a cardioprotective mechanism against myocellular death and cardiac dysfunction resulting from reperfusion of the ischemic heart. At present, the precise list of mediators involved in IP and the pathways of their mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5436e8dacafefa6e797b715e1498f58a
https://doi.org/10.1152/ajpheart.00599.2004
https://doi.org/10.1152/ajpheart.00599.2004
Autor:
Miriam Isola, Irene Mavelli, Francesca Di Pancrazio, Pasquale Pagliaro, Giovanna Lippe, Gianni Losano, David A. Harris
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1659:52-62
A method has been developed to allow the level of F 0 F 1 ATP synthase capacity and the quantity of IF 1 bound to this enzyme be measured in single biopsy samples of goat heart. ATP synthase capacity was determined from the maximal mitochondrial ATP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e2561bd0a90dd9e4091743738b4657
https://doi.org/10.1016/j.bbabio.2004.07.009
https://doi.org/10.1016/j.bbabio.2004.07.009
Autor:
Daniele Mancardi, Gianni Losano, Pasquale Pagliaro, Donatella Gattullo, Antonio Crisafulli, Raffaella Rastaldo, Claudia Penna
Publikováno v:
Acta Physiologica Scandinavica. 182:11-20
Aims: Acetylcholine (ACh) is known to reduce the contractility of the heart by acting on myocardial muscarinic M2 receptors. ACh induces also an endothelial-dependent vasodilatation by causing the release of nitric oxide (NO), prostacyclin and endoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dcce6e9abce7b16b3c2a08423d36d9b
https://doi.org/10.1111/j.1365-201x.2004.01339.x
https://doi.org/10.1111/j.1365-201x.2004.01339.x