Zobrazeno 1 - 10
of 541
pro vyhledávání: '"Giannakakou, P"'
Akademický článek
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Autor:
Seaho Kim, CheukMan C Au, Mohd Azrin Bin Jamalruddin, Naira Essam Abou-Ghali, Eiman Mukhtar, Luigi Portella, Adeline Berger, Daniel Worroll, Prerna Vatsa, David S Rickman, David M Nanus, Paraskevi Giannakakou
Publikováno v:
eLife, Vol 11 (2022)
Expression of the AR splice variant, androgen receptor variant 7 (AR-V7), in prostate cancer is correlated with poor patient survival and resistance to AR targeted therapies and taxanes. Currently, there is no specific inhibitor of AR-V7, while the m
Externí odkaz:
https://doaj.org/article/2dbc4df1b5624c61b2a0b3917507799c
Autor:
Ada Gjyrezi, Giuseppe Galletti, Jiaren Zhang, Daniel Worroll, Michael Sigouros, Seaho Kim, Victoria Cooley, Karla V. Ballman, Allyson J. Ocean, Manish A. Shah, Joseph M. Scandura, Andrea Sboner, David M. Nanus, Himisha Beltran, Scott Tagawa, Paraskevi Giannakakou
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Ada Gjyrezi et al. show that ddPCR can be used to accurately measure androgen receptor variant (AR-V) expression levels in single circulating tumor cells (CTCs) from prostate cancer patients. They show that current methods for isolating CTCs tend to
Externí odkaz:
https://doaj.org/article/54507da59cc5412fa5d4da9b3a601956
Autor:
Anna Koumarianou, Anastasios Ntavatzikos, David Symeonidis, Christos Vallilas, Maria Giannakakou, Georgios Papaxoinis, Spyridon Xynogalos, Ioannis Boukovinas, Stamatina Demiri, Katerina Kampoli, Georgios Oikonomopoulos, Epaminontas Samantas, Eleni Res, Nikolaos Androulakis, Georgia Vourli, Ioannis Souglakos, Michalis Karamouzis
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1267 (2023)
Background: Trifluridine/tipiracil (FTD/TPI) is an oral antimetabolite agent comprised of trifluridine, a thymidine-based nucleoside analogue that inhibits cell proliferation following its incorporation into DNA, and tipiracil that helps maintain the
Externí odkaz:
https://doaj.org/article/127365e0afa7497098993b8317173877
Autor:
Neel S. Madhukar, Prashant K. Khade, Linda Huang, Kaitlyn Gayvert, Giuseppe Galletti, Martin Stogniew, Joshua E. Allen, Paraskevi Giannakakou, Olivier Elemento
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Drug target identification is a crucial step in drug development. Here, the authors introduce a Bayesian machine learning framework that integrates multiple data types to predict the targets of small molecules, enabling identification of a new set of
Externí odkaz:
https://doaj.org/article/fd2f68d27a0449ed8826ad49e3a65d1c
Autor:
Yiyuan Liu, Bobbie Pelham-Webb, Dafne Campigli Di Giammartino, Jiexi Li, Daleum Kim, Katsuhiro Kita, Nestor Saiz, Vidur Garg, Ashley Doane, Paraskevi Giannakakou, Anna-Katerina Hadjantonakis, Olivier Elemento, Effie Apostolou
Publikováno v:
Cell Reports, Vol 19, Iss 7, Pp 1283-1293 (2017)
During mitosis, transcription is halted and many chromatin features are lost, posing a challenge for the continuity of cell identity, particularly in fast cycling stem cells, which constantly balance self-renewal with differentiation. Here we show th
Externí odkaz:
https://doaj.org/article/a34a1a992bc64ae499cff97a102695a3
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
Autor:
Andrew J Armstrong, Santosh Gupta, Patrick Healy, Gabor Kemeny, Beth Leith, Michael R Zalutsky, Charles Spritzer, Catrin Davies, Colin Rothwell, Kathryn Ware, Jason A Somarelli, Kris Wood, Thomas Ribar, Paraskevi Giannakakou, Jiaren Zhang, Drew Gerber, Monika Anand, Wen-Chi Foo, Susan Halabi, Simon G Gregory, Daniel J George
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216934 (2019)
BackgroundRadium-223 is a targeted alpha-particle therapy that improves survival in men with metastatic castration resistant prostate cancer (mCRPC), particularly in men with elevated serum levels of bone alkaline phosphatase (B-ALP). We hypothesized
Externí odkaz:
https://doaj.org/article/a30bb6a9379947f68513ccbaae968fe8
Autor:
Diamond, E., Molina, A.M., Carbonaro, M., Akhtar, N.H., Giannakakou, P., Tagawa, S.T., Nanus, D.M.
Publikováno v:
In Critical Reviews in Oncology / Hematology December 2015 96(3):518-526