Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Gianmaria, Miolo"'
Autor:
Silvio Ken Garattini, Debora Basile, Valli’ De Re, Giulia Brisotto, Gianmaria Miolo, Vincenzo Canzonieri, Giuseppe Aprile, Carla Corvaja, Silvia Buriolla, Enrico Garattini, Fabio Puglisi
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundGastric cancer is a heterogeneous collection of tumors characterized by low survival rates. All-trans retinoic acid (retinoic-acid) is a clinically useful therapeutic agent belonging to the chemical family of retinoids, which consists of bo
Externí odkaz:
https://doaj.org/article/05bc3cdb6664411c936872f61ba7e927
Autor:
Gianmaria Miolo, Angela Buonadonna, Davide Lombardi, Simona Scalone, Andrea Lauretta, Lara Della Puppa, Giuseppe Corona
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundIn the landscape of metastatic soft tissue sarcoma (mSTS) treatment, anthracyclines have shown efficacy; however, their associated toxicity imposes significant limitations, especially in frail elderly patients with mSTS who are highly susce
Externí odkaz:
https://doaj.org/article/25466964f75d46e5ae5ffc260ee45969
Autor:
Gianmaria Miolo, Wally Marus, Angela Buonadonna, Lucia Da Ros, Lara Della Puppa, Giuseppe Corona
Publikováno v:
Diagnostics, Vol 14, Iss 9, p 888 (2024)
The immunohistochemical assessment of mismatch repair (MMR) proteins represents a pivotal screening tool for identifying Lynch syndrome (LS)-related cancers, as the loss of their expression often indicates MMR dysfunction associated with genetic or e
Externí odkaz:
https://doaj.org/article/1b3f1944a3d848f6a86b1e000093920d
Autor:
Alessia Vignoli, Gianmaria Miolo, Leonardo Tenori, Angela Buonadonna, Davide Lombardi, Agostino Steffan, Simona Scalone, Claudio Luchinat, Giuseppe Corona
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107678- (2023)
Summary: Soft tissue sarcomas (STSs) are rare malignant tumors that are difficult to prognosticate using currently available instruments. Omics sciences could provide more accurate and individualized survival predictions for patients with metastatic
Externí odkaz:
https://doaj.org/article/9c2bcc1a4d4b4a6fb7305b01edc3ff10
Autor:
Giuseppe Corona, Emanuela Di Gregorio, Angela Buonadonna, Davide Lombardi, Simona Scalone, Agostino Steffan, Gianmaria Miolo
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Objective: Trabectedin is an anti-cancer drug commonly used for the treatment of patients with metastatic soft tissue sarcoma (mSTS). Despite its recognized efficacy, significant variability in pharmacological response has been observed among mSTS pa
Externí odkaz:
https://doaj.org/article/7ec5f0e549b9450fba7da53b55bdc270
Autor:
Gianmaria Miolo, Angela Buonadonna, Simona Scalone, Davide Lombardi, Lara Della Puppa, Agostino Steffan, Giuseppe Corona
Publikováno v:
Metabolites, Vol 13, Iss 10, p 1035 (2023)
Metastatic soft-tissue sarcomas (mSTS) encompass a highly heterogeneous group of rare tumours characterized by different clinical behaviours and outcomes. Currently, prognostic factors for mSTS are very limited, posing significant challenges in predi
Externí odkaz:
https://doaj.org/article/d2afda10f6d54180a6edb2b604c59d2a
Autor:
Valli De Re, Laura Caggiari, Mariangela De Zorzi, Valentina Fanotto, Gianmaria Miolo, Fabio Puglisi, Renato Cannizzaro, Vincenzo Canzonieri, Agostino Steffan, Piero Farruggia, Egesta Lopci, Emanuele S. G. d’Amore, Roberta Burnelli, Lara Mussolin, Maurizio Mascarin
Publikováno v:
Infectious Agents and Cancer, Vol 15, Iss 1, Pp 1-9 (2020)
Abstract Background EBV produces miRNAs with important functions in cancer growth, tumor invasion and host immune surveillance. The discovery of EBV miR-BARTs is recent, and most of their functions are still unknown. Nonetheless, some new studies und
Externí odkaz:
https://doaj.org/article/60d10087c67341a291fdb61c04170598
Autor:
Elena Muraro, Mariangela De Zorzi, Gianmaria Miolo, Davide Lombardi, Simona Scalone, Simon Spazzapan, Samuele Massarut, Tiziana Perin, Riccardo Dolcetti, Agostino Steffan, Valli De Re
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Trastuzumab induced a high rate of pathological Complete Response (pCR) in patients affected by locally advanced HER2-positive Breast Cancer (HER2-BC), by exploiting immune-mediated mechanisms as Antibody-Dependent Cell Cytotoxicity (ADCC) involving
Externí odkaz:
https://doaj.org/article/466ec35c7331483ba857a5cf310b0370
Autor:
Lara Alessandrini, Francesco Sopracordevole, Giulio Bertola, Simona Scalone, Martina Urbani, Gianmaria Miolo, Tiziana Perin, Fabrizio Italia, Vincenzo Canzonieri
Publikováno v:
Diagnostic Pathology, Vol 12, Iss 1, Pp 1-9 (2017)
Abstract Background Endometrial stromal sarcomas arising in extrauterine and extraovarian sites, in the absence of a primary uterine lesion are quite rare, especially in the absence of endometriosis. They usually present as an abdominal or pelvic mas
Externí odkaz:
https://doaj.org/article/14bb9fd6060945f384740f9e77e9deda
Autor:
Federico Innocenti, Gianna Tabaro, Gianmaria Miolo, Blase N. Polite, Angela Buonadonna, Quan Mai, Elizabeth Gray, Bianca Posocco, Elena Marangon, Manish R. Sharma, Giuseppe Toffoli
Purpose: UGT1A1*28 confers a higher risk of toxicity in patients treated with irinotecan. Patients with *1/*1 and *1/*28 genotypes might tolerate higher than standard doses of irinotecan. We aimed to identify the MTD of irinotecan in patients with me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162e90e00c70a482c4f0179d719a3546
https://doi.org/10.1158/1078-0432.c.6526580
https://doi.org/10.1158/1078-0432.c.6526580
