Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Gianluigi Ardissino"'
Autor:
Elisa Varrone, Domenica Carnicelli, Xiaohua He, Marco Grasse, Karin Stampfer, Silke Huber, Sára Kellnerová, Pier Luigi Tazzari, Francesca Ricci, Paola Paterini, Gianluigi Ardissino, Stefano Morabito, Dorothea Orth-Höller, Reinhard Würzner, Maurizio Brigotti
Publikováno v:
Toxins, Vol 15, Iss 12, p 690 (2023)
Typical hemolytic uremic syndrome (HUS) is mainly caused by Shiga toxin-producing Escherichia coli (STEC) releasing Shiga toxin 2 (Stx2). Two different structures of this AB5 toxin have been described: uncleaved, with intact B and A chains, and cleav
Externí odkaz:
https://doaj.org/article/0dc88a36b3994ed8a657281fccd7ff6f
Autor:
Sára Kellnerová, Silke Huber, Mariam Massri, Verena Fleischer, Klemens Losso, Bettina Sarg, Leopold Kremser, Heribert Talasz, Xiaohua He, Elisa Varrone, Maurizio Brigotti, Gianluigi Ardissino, Dorothea Orth-Höller, Reinhard Würzner
Publikováno v:
Microorganisms, Vol 11, Iss 10, p 2487 (2023)
Shiga toxins (Stxs), especially the Stx2a subtype, are the major virulence factors involved in enterohemorrhagic Escherichia coli (EHEC)-associated hemolytic uremic syndrome (eHUS), a life-threatening disease causing acute kidney injury, especially i
Externí odkaz:
https://doaj.org/article/1ca4c0dd124949ba951378c251c8cc47
Autor:
Monica Fumagalli, Dario Ronchi, Maria Francesca Bedeschi, Arianna Manini, Gloria Cristofori, Fabio Mosca, Robertino Dilena, Monica Sciacco, Simona Zanotti, Daniela Piga, Gianluigi Ardissino, Fabio Triulzi, Stefania Corti, Giacomo P. Comi, Leonardo Salviati
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 32, Iss , Pp 100887- (2022)
Mitochondrial DNA (mtDNA) depletion syndromes are disorders characterized by infantile-onset, severe progression, and the drastic loss of mtDNA content in affected tissues. In a patient who showed severe hypotonia, proximal tubulopathy and sensorineu
Externí odkaz:
https://doaj.org/article/96c54ae9f7bc4b18b52893b3aafa3063
Autor:
Gianluigi Ardissino, Selena Longhi, Luigi Porcaro, Giulia Pintarelli, Bice Strumbo, Valentina Capone, Donata Cresseri, Giulia Loffredo, Francesca Tel, Stefania Salardi, Martina Sgarbanti, Laura Martelli, Evangeline Millicent Rodrigues, Nicolò Borsa-Ghiringhelli, Giovanni Montini, Manuela Seia, Massimo Cugno, Fabio Carfagna, Dario Consonni, Silvana Tedeschi
Publikováno v:
Kidney International Reports, Vol 6, Iss 6, Pp 1614-1621 (2021)
Introduction: Atypical hemolytic uremic syndrome (aHUS) is mainly due to complement regulatory gene abnormalities with a dominant pattern but incomplete penetrance. Thus, healthy carriers can be identified in any family of aHUS patients, but it is un
Externí odkaz:
https://doaj.org/article/9c4a411b84e947be84e68998d1311488
Autor:
Valeria Grancini, Federica Alessandra Vianello, Santo Colosimo, Alessia Gaglio, Veronica Resi, Maura Arosio, Gianluigi Ardissino, Giovanni Montini, Emanuela Orsi
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
We report the case of a 3-year-old girl admitted to her town emergency department for fever (39°C) associated with diarrhea, generalized edema, oliguria, and drowsiness. The blood test revealed metabolic acidosis, leucocytosis, increased inflammator
Externí odkaz:
https://doaj.org/article/5a2518f2922e48d4b8beb77b844952a6
Publikováno v:
Pharmaceuticals, Vol 15, Iss 7, p 845 (2022)
Thrombotic microangiopathy (TMA) is a complication that may occur after autologous or allogeneic hematopoietic stem cell transplantation (HSCT) and is conventionally called transplant-associated thrombotic microangiopathy (TA-TMA). Despite the many e
Externí odkaz:
https://doaj.org/article/f7a7f715ed42473f9554ebf9b67ed41c
Publikováno v:
Case Reports in Pediatrics, Vol 2021 (2021)
We report on the case of a 7-year-old boy with Shiga toxin-producing Escherichia coli-related hemolytic uremic syndrome (STEC-HUS), initially presenting with abdominal pain as the only clinical feature and thus requiring differential diagnosis with a
Externí odkaz:
https://doaj.org/article/5ebe3fa668d04343a7a84716b7595b53
Autor:
Antonio Piralla, Giovanna Lunghi, Gianluigi Ardissino, Alessia Girello, Marta Premoli, Erika Bava, Milena Arghittu, Maria Rosaria Colombo, Alessandra Cognetto, Patrizia Bono, Giulia Campanini, Piero Marone, Fausto Baldanti
Publikováno v:
BMC Microbiology, Vol 17, Iss 1, Pp 1-10 (2017)
Abstract Background Acute gastroenteritis is a common cause of morbidity and mortality in humans worldwide. The rapid and specific identification of infectious agents is crucial for correct patient management. However, diagnosis of acute gastroenteri
Externí odkaz:
https://doaj.org/article/05ce135cadaa44d6ba093cab98a44ef0
Autor:
Valentina Arfilli, Domenica Carnicelli, Gianluigi Ardissino, Erminio Torresani, Gaia Scavia, Maurizio Brigotti
Publikováno v:
Toxins, Vol 7, Iss 11, Pp 4564-4576 (2015)
Shiga toxins (Stx) have a definite role in the development of hemolytic uremic syndrome in children with hemorrhagic colitis caused by pathogenic Stx-producing Escherichia coli (STEC) strains. The dramatic effects of these toxins on the microvasculat
Externí odkaz:
https://doaj.org/article/ce47248dd2504727a371f68992f48324
Autor:
Gianluigi Ardissino, Michela Perrone, Francesca Tel, Sara Testa, Amelia Morrone, Ilaria Possenti, Francesco Tagliaferri, Robertino Dilena, Francesca Menni
Publikováno v:
Case Reports in Pediatrics, Vol 2017 (2017)
Hemolytic uremic syndrome (HUS) is an unrare and severe thrombotic microangiopathy (TMA) caused by several pathogenetic mechanisms among which Shiga toxin-producing Escherichia coli infections and complement dysregulation are the most common. However
Externí odkaz:
https://doaj.org/article/118e02f508f7423dbd6b059e124dd79a