Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Gianluca Molla"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/0d8aa1d0694e43d6be7e7f38cfc0f9d8
Publikováno v:
Symmetry, Vol 15, Iss 5, p 1017 (2023)
Biomolecules are frequently chiral compounds, existing in enantiomeric forms. Amino acids represent a meaningful example of chiral biological molecules. Both L- and D-amino acids play key roles in the biochemical structure and metabolic processes of
Externí odkaz:
https://doaj.org/article/56b1c22a35b14b2d80192e991fbc82ad
Autor:
Marco Orlando, Gianluca Molla, Pietro Castellani, Valentina Pirillo, Vincenzo Torretta, Navarro Ferronato
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3877 (2023)
The accumulation of synthetic plastic waste in the environment has become a global concern. Microbial enzymes (purified or as whole-cell biocatalysts) represent emerging biotechnological tools for waste circularity; they can depolymerize materials in
Externí odkaz:
https://doaj.org/article/90f1eca3db8946eca6d062a0c05c5737
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
In recent years, the D-enantiomers of amino acids have been recognized as natural molecules present in all kingdoms, playing a variety of biological roles. In humans, d-serine and d-aspartate attracted attention for their presence in the central nerv
Externí odkaz:
https://doaj.org/article/e8eb86c44be443b2a952d9c312bb6e23
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 858 (2022)
In 2002, the novel human gene G72 was associated with schizophrenia susceptibility. This gene encodes a small protein of 153 amino acids, named pLG72, which represents a rare case of primate-specific protein. In particular, the rs2391191 single nucle
Externí odkaz:
https://doaj.org/article/7d2f2eb8250e4036b0f3ae8a9ef013da
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 264 (2021)
Enzymatic degradation is a promising green approach to bioremediation and recycling of the polymer poly(ethylene terephthalate) (PET). In the past few years, several PET-hydrolysing enzymes (PHEs) have been discovered, and new variants have been evol
Externí odkaz:
https://doaj.org/article/b2d67844ea5b4906845f00138fba171e
Autor:
Heiko Brennenstuhl, Miroslava Didiasova, Birgit Assmann, Mariarita Bertoldi, Gianluca Molla, Sabine Jung-Klawitter, Oya Kuseyri Hübschmann, Julian Schröter, Thomas Opladen, Ritva Tikkanen
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8578 (2020)
Succinic semialdehyde dehydrogenase deficiency (SSADHD) is a rare, monogenic disorder affecting the degradation of the main inhibitory neurotransmitter γ-amino butyric acid (GABA). Pathogenic variants in the ALDH5A1 gene that cause an enzymatic dysf
Externí odkaz:
https://doaj.org/article/b42e97c8a9b2402793f8694b5b45732f
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3206 (2020)
In nature, the D-enantiomers of amino acids (D-AAs) are not used for protein synthesis and during evolution acquired specific and relevant physiological functions in different organisms. This is the reason for the surge in interest and investigations
Externí odkaz:
https://doaj.org/article/cf7d3498606748a7bb03656fcde31d40
Publikováno v:
Frontiers in Molecular Biosciences, Vol 5 (2018)
pLG72 is a small, primate-specific protein of 153 amino acids. It is the product of the G72 gene, expressed in testis, spinal cord, and brain. The presence of G72 transcript and pLG72 has recurrently been called into question, however G72 mRNA and pL
Externí odkaz:
https://doaj.org/article/e49930c4b6534dc2bbf2efb203802e9b
Autor:
Gianluca Molla
Publikováno v:
Frontiers in Molecular Biosciences, Vol 4 (2017)
D-amino acid oxidase (DAAO) catalyzes the oxidative deamination of several neutral D-amino acids and is the enzyme mainly responsible (together with serine racemase) for degrading D-serine (D-Ser) in the central nervous system of mammals. This D-amin
Externí odkaz:
https://doaj.org/article/a8fcba29fb5346ccb757cde1113e9cc6