Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gianluca L. Perrucci"'
Autor:
Sara Rega, Floriana Farina, Silvia Bouhuis, Silvia de Donato, Mattia Chiesa, Paolo Poggio, Laura Cavallotti, Giorgia Bonalumi, Ilaria Giambuzzi, Giulio Pompilio, Gianluca L. Perrucci
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-27 (2023)
Abstract Background Thoracic aortic aneurysm (TAA) is a serious condition that affects the aorta, characterized by the dilation of its first segment. The causes of TAA (e.g., age, hypertension, genetic syndromes) are heterogeneous and contribute to t
Externí odkaz:
https://doaj.org/article/4141eb53329d41b296138e8550d9e87a
Autor:
Susan Marelli, Emanuele Micaglio, Jacopo Taurino, Paolo Salvi, Erica Rurali, Gianluca L. Perrucci, Claudia Dolci, Nathasha Samali Udugampolage, Rosario Caruso, Davide Gentilini, Giuliana Trifiro’, Edward Callus, Alessandro Frigiola, Carlo De Vincentiis, Carlo Pappone, Gianfranco Parati, Alessandro Pini
Publikováno v:
Diagnostics, Vol 13, Iss 13, p 2284 (2023)
Marfan syndrome (MFS) is a rare inherited autosomic disorder, which encompasses a variety of systemic manifestations caused by mutations in the Fibrillin-1 encoding gene (FBN1). Cardinal clinical phenotypes of MFS are highly variable in terms of seve
Externí odkaz:
https://doaj.org/article/eaf5ac0117964361a1de4f2427a8afe8
Autor:
Donato Moschetta, Matteo Nicola Dario Di Minno, Benedetta Porro, Gianluca L. Perrucci, Vincenza Valerio, Valentina Alfieri, Ilaria Massaiu, Alexander N. Orekhov, Alessandro Di Minno, Paola Songia, Viviana Cavalca, Veronika A. Myasoedova, Paolo Poggio
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
IntroductionOsteopontin (OPN) is involved in ectopic calcification. Its circulating form is upregulated in coronary artery disease (CAD) patients. Circulating OPN levels positively correlate with oxidative stress, one of the major triggers of endothe
Externí odkaz:
https://doaj.org/article/ce583c892ddf41d19ae42225c973a048
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 7, Pp 823-835 (2017)
Arrhythmogenic cardiomyopathy is a rare genetic disease that is mostly inherited as an autosomal dominant trait. It is associated predominantly with mutations in desmosomal genes and is characterized by the replacement of the ventricular myocardium w
Externí odkaz:
https://doaj.org/article/7624bf1a964a410c84889ec2ac844d9d
Autor:
Gianluca L. Perrucci, Erica Rurali, Maria Corlianò, Maria Balzo, Michela Piccoli, Donato Moschetta, Alessandro Pini, Raffaella Gaetano, Carlo Antona, Gustavo Egea, Gunter Fischer, Miroslav Malešević, Francesco Alamanni, Elisa Cogliati, Adolfo Paolin, Giulio Pompilio, Patrizia Nigro
Publikováno v:
Cells, Vol 9, Iss 1, p 154 (2020)
Background: Marfan syndrome (MFS) is a genetic disease, characterized by thoracic aortic aneurysm (TAA), which treatment is to date purely surgical. Understanding of novel molecular targets is mandatory to unveil effective pharmacological approaches.
Externí odkaz:
https://doaj.org/article/13b419b378ad4306b254379f0d9e48c8
Autor:
Aoife Gowran, Marco Rasponi, Roberta Visone, Patrizia Nigro, Gianluca L. Perrucci, Stefano Righetti, Marco Zanobini, Giulio Pompilio
Publikováno v:
Stem Cells International, Vol 2016 (2016)
A mere 9 years have passed since the revolutionary report describing the derivation of induced pluripotent stem cells from human fibroblasts and the first in-patient translational use of cells obtained from these stem cells has already been achieved.
Externí odkaz:
https://doaj.org/article/f76266b7664b47ff934aff0d8e2e765c
Autor:
Donato Moschetta, Matteo Nicola Dario Di Minno, Benedetta Porro, Gianluca L. Perrucci, Vincenza Valerio, Valentina Alfieri, Ilaria Massaiu, Alexander N. Orekhov, Alessandro Di Minno, Paola Songia, Viviana Cavalca, Veronika A. Myasoedova, Paolo Poggio
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology, Vol 11 (2020)
Introduction Osteopontin (OPN) is involved in ectopic calcification. Its circulating form is upregulated in coronary artery disease (CAD) patients. Circulating OPN levels positively correlate with oxidative stress, one of the major triggers of endoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd0dd68eadbe0c4a283df66bae769bd0
https://pubmed.ncbi.nlm.nih.gov/32848891
https://pubmed.ncbi.nlm.nih.gov/32848891